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بهینهسازی فرآیند استخراج مواد موثره تفاله پرتقال با استفاده از آب تحت بحرانی | ||
| تحقیقات مهندسی صنایع غذایی | ||
| مقاله 1، دوره 25، شماره 1 - شماره پیاپی 80، فروردین 1405، صفحه 1-20 اصل مقاله (1.31 M) | ||
| نوع مقاله: مقاله پژوهشی | ||
| شناسه دیجیتال (DOI): 10.22092/fooder.2026.368574.1416 | ||
| نویسندگان | ||
| نیلوفر قاسمپور1؛ امیرحسین الهامی راد2؛ مجید جوانمرد* 3؛ الهام آذرپژوه* 4؛ محمد آرمین5 | ||
| 1گروه علوم و صنایع غذایی، واحد سبزوار، دانشگاه آزاد اسلامی، سبزوار، ایران | ||
| 2دانشگاه ازاد اسلامی واحد سبزوار | ||
| 3lمدیر گروه صنایع غذایی و تبدیلی - سازمان پژوهش های ایران | ||
| 4دانشیار پژوهش بخش تحقیقات فنی و مهندسی کشاورزی، مرکز تحقیقات و آموزش کشاورزی و منابع طبیعی استان خراسان رضوی، سازمان تحقیقات، | ||
| 5عضو هیات علمی دانشگاه آزاد اسلامی واحد سبزوار | ||
| چکیده | ||
| پژوهش حاضر با هدف استفادۀ بهینه از تفالۀ پرتقال بهعنوان پسماند کشاورزی و کارخانههای تولید آب پرتقال و استخراج ترکیبات زیستفعال (ضداکسایشی و ضدمیکروبی) اجرا گردید. بهمنظور بهینه سازی راندمان استخراج، میزان ترکیبات فنلی و فعالیت آنتی اکسیدانی عصاره استخراجشده با آب تحت بحرانی از طرح مرکزی وجهمحور Face-Centered CCD استفاده شد. دمای استخراج (120، 140 و 160 درجه سلسیوس) و زمان استخراج (20، 30 و 40 دقیقه) بهعنوان متغیرهای استخراج ترکیبات زیست فعال در نظر گرفته شدند. بر اساس مدل های حاصل، شرایط بهینۀ استخراج شامل دمای 142.87درجة سلسیوس و زمان 39.97 دقیقه تعیین شد. در این شرایط، بازده استخراج 13.94 درصد، میزان ترکیبات فنلی کل454.80میلیگرم گالیک اسید در صد گرم و قدرت مهار رادیکال آزاد 51.78 درصد به دست آمد. استخراج در نقطۀ بهینه نتایج بهدست آمده را تأیید کرد. علاوه بر این، عصارة استخراجشده دارای خواص ضدمیکروبی مؤثر بود، بهطوریکه حداقل غلظت بازدارندگی عصاره علیه قارچ پنیسیلیوم سیترینیوم و آسپرژیلوس نایجر به ترتیب 10 و 5 درصد بود، درحالیکه این مقدار برای داروی فلوکنازول 1 درصد گزارش شده است. این مطالعه کارایی بالای فرآیند آب تحت بحرانی را در استخراج ترکیبات زیستفعال از ضایعات کشاورزی به اثبات رساند و آن را بهعنوان روشی سازگار با محیطزیست و مؤثر برای تولید ترکیبات ارزشمند معرفی کرد. | ||
| کلیدواژهها | ||
| تفاله پرتقال؛ آب تحت بحرانی؛ ترکیبات فنلی؛ ضدمیکروبی | ||
| عنوان مقاله [English] | ||
| Optimization of the Extraction Process of Bioactive Compounds from Orange Peel Waste Using Subcritical Water | ||
| نویسندگان [English] | ||
| niloofar Ghasempour1؛ Amir hussein Elhami Rad2؛ MAJID javanmardi3؛ Elham Azarpazhooh4؛ Mohammad Armin5 | ||
| 1Group of Food Science and Industry, Ehad Sabzvar, University of Azad Islami, Sabzvar, Iran | ||
| 2University of Azad Islami One Green Garden | ||
| 3Director of Food Industry and Processing Department - Iran Research Organization | ||
| 4Associate Professor Department of Agricultural Engineering Institute, Khorasan Razavi Agricultural and Natural Resources Research and Education Center, AREEO, Address: P.O.Box 91735-488, Mashhad-Iran http://kanrrc.areo.ir Tel&Fax(work) | ||
| 5Member of the academic staff of Islamic Azad University, Sabzevar branch | ||
| چکیده [English] | ||
| This study aimed to optimize the extraction of bioactive compounds (antioxidant and antimicrobial) from orange pomace, a byproduct of orange juice production. A Face-Centered CCD design was employed to maximize extraction yield, total phenolic content, and antioxidant activity using subcritical water. Extraction temperature (120, 140, and 160°C) and time (20, 30, and 40 minutes) were selected as key variables. The optimal conditions, determined through modeling, were 142.87°C and 39.97 minutes. Under these conditions, the extraction yield reached 13.94%, total phenolic content (TPC) was 454.80 mg gallic acid equivalent (GAE) per 100 g, and free radical scavenging activity (DPPH) was 51.78%. Verification experiments confirmed these results. Additionally, the extracted compounds exhibited strong antimicrobial activity, with minimum inhibitory concentrations (MIC) of 10% and 5% against Penicillium citrinum and Aspergillus niger, respectively, compared to 1% for fluconazole. This study highlights the efficiency of subcritical water extraction in recovering bioactive compounds from agricultural byproducts, emphasizing its potential as a sustainable and effective method for producing valuable bioactive materials. | ||
| کلیدواژهها [English] | ||
| phenolic compounds, orange peel waste, subcritical water, antimicrobial properties | ||
| مراجع | ||
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Ahmadian-Kouchaksaraie, Z. Niazmand, R. and Najaf Najafi, M. 2016. Optimization of the subcritical water extraction of phenolic antioxidants from Crocus sativus petals of saffron industry residues: Box-Behnken design and principal component analysis. Innovative Food Science & Emerging Technologies. 36, 234-244. https://doi.org/10.1016/j.ifset.2016.07.005 Brand-Williams, W. Cuvelier, M. E. and Berset, C. 1995. Use of a free-radical method to evaluate antioxidant activity. Lebensmittel-Wissenschaft & Technologie. 28, 25-30. https://doi.org/10.1016/S0023-6438(95)80008-5 Chemat, F. Abert Vian, M. Ravi, H. K. Khadhraoui, B. Hilali, S. Perino, S. and Fabiano-Tixier, A. S. 2019. Review of alternative solvents for green extraction of food and natural products: Panorama, principles, applications and prospects. Molecules. 24(16), 3007. https://doi.org/10.3390/molecules24163007 Cheng, Y. Xue, F. Yu, S. Du, S. and Yang, Y. 2021. Subcritical water extraction of natural products. Molecules. 26(13), 4004. https://doi.org/10.3390/molecules26134004 Deshpande, S. N. 2013. Preliminary phytochemical analysis and in vitro investigation of antibacterial activity of Acacia nilotica against clinical isolates. Journal of Pharmacognosy and Phytochemistry. 1, 23-27. FAO (Food and Agriculture Organization of the United Nations). 2017. Processed statistical bulletin 2016. Rome, Italy: FAO. Gokoglu, N. 2019. Novel natural food preservatives and applications in seafood preservation: A review. Journal of the Science of Food and Agriculture. 99(5), 2068-2077. https://doi.org/10.1002/jsfa.9416 Huang, L. Liu, J. Addy, M. Ding, B. Cheng, Y. Peng, P. and Ruan, R. 2020. Physicochemical and emulsifying properties of orange fibers stabilized oil-in-water emulsions. LWT Food Science and Technology. 133, 110054. https://doi.org/10.1016/j.lwt.2020.110054 Ibrahim, S. Santos, R. and Bowra, S. 2019. Optimization of subcritical water mediated extraction of apple pomace polyphenolics and their antioxidant activity. Journal of Chromatography Separation Techniques. 9(5), 1-10. Kumar, M. Y. Dutta, R. Prasad, D. and Misra, K. 2011. Subcritical water extraction of antioxidant compounds from seabuckthorn (Hippophae rhamnoides) leaves for the comparative evaluation of antioxidant activity. Food Chemistry. 127(3), 1309-1316. https://doi.org/10.1016/j.foodchem.2011.01.088 Lachos-Perez, D. Baseggio, A. M. Mayanga-Torres, P. C. Junior, M. R. M. Rostagno, M. A. Martínez, J. and Forster-Carneiro, T. 2018. Subcritical water extraction of flavanones from defatted orange peel. The Journal of Supercritical Fluids. 138, 7-16. https://doi.org/10.1016/j.supflu.2018.03.015 Lobiuc, A. Pavăl, N.E. Mangalagiu, I. I. Gheorghiță, R. Teliban, G.C. Amăriucăi-Mantu, D. and Stoleru, V. 2023. Future Antimicrobials: Natural and Functionalized Phenolics. Molecules. 28(3), 1114. https://doi.org/10.3390/molecules28031114 Lv, X. Zhao, S. Ning, Z. Zeng, H. Shu, Y. Tao, O. and Liu, Y. 2015. Citrus fruits as a treasure trove of active natural metabolites that potentially provide benefits for human health. Chemistry Central Journal. 9, 1-14. https://doi.org/10.1186/s13065-015-0145-9 Majerska, J. Michalska, A. and Figiel, A. 2019. A review of new directions in managing fruit and vegetable processing by-products. Trends in Food Science & Technology. 88, 207-219. https://doi.org/10.1016/j.tifs.2019.03.021 Maran, J. P. Priya, B. Al-Dhabi, N. A. Ponmurugan, K. Moorthy, I. G. and Sivarajasekar, N. 2017. Ultrasound assisted citric acid mediated pectin extraction from industrial waste of Musa balbisiana. Ultrasonics Sonochemistry. 35, 204-209. https://doi.org/10.1016/j.ultsonch.2016.09.019 Masala, V. Jokić, S. Aladić, K. Molnar, M. and Tuberoso, C. I. G. 2024. Exploring phenolic compounds extraction from saffron (C. sativus) floral by-products using ultrasound-assisted extraction, deep eutectic solvent extraction, and subcritical water extraction. Molecules. 29(11), 2600. https://doi.org/10.3390/molecules29112600 Panwar, D. Saini, A. Panesar, P. S. and Chopra, H. K. 2021. Unraveling the scientific perspectives of citrus by-products utilization: Progress towards circular economy. Trends in Food Science & Technology. 111, 549-562. https://doi.org/10.1016/j.tifs.2021.03.018 Papoutsis, K. Pristijono, P. Golding, J. B. Stathopoulos, C. E. Bowyer, M. C. Scarlett, C. J. and Vuong, Q. V. 2018. Screening the effect of four ultrasound-assisted extraction parameters on hesperidin and phenolic acid content of aqueous citrus pomace extracts. Food Bioscience. 21, 20-26. https://doi.org/10.1016/j.fbio.2017.11.001 Pinto, D. Vieira, E. F. Peixoto, A. F. Freire, C. Freitas, V. Costa, P. and Rodrigues, F. 2021. Optimizing the extraction of phenolic antioxidants from chestnut shells by subcritical water extraction using response surface methodology. Food Chemistry. 334, 127521. https://doi.org/10.1016/j.foodchem.2020.127521 Putnik, P. Bursać Kovačević, D. Režek Jambrak, A. Barba, F. J. Cravotto, G. Binello, A. and Shpigelman, A. 2017. Innovative "green" and novel strategies for the extraction of bioactive added value compounds from citrus wastes—A review. Molecules. 22(5), 680. https://doi.org/10.3390/molecules22050680 Saberian, H. Hosseini, F. and Bolourian, Sh. 2017. Optimization of extraction condition of chlorophyll from alfalfa and investigating its quality and quantity properties in comparison to different plant resources. Iranian Food Science and Technology Research Journal. 14(71), 47-57. Shitu, A. Izhar, S. and Tahir, T. M. 2015. Sub-critical water as a green solvent for production of valuable materials from agricultural waste biomass: A review of recent work. Recent Patents on Food, Nutrition & Agriculture. 7(1), 42-48. https://doi.org/10.2174/2212798407666150401103712 Sulejmanović, M. Milić, N. Mourtzinos, I. Nastić, N. Kyriakoudi, A. Drljača, J. and Vidović, S. 2024. Ultrasound-assisted and subcritical water extraction techniques for maximal recovery of phenolic compounds from raw ginger herbal dust toward in vitro biological activity investigation. Food Chemistry. 437, 137774. https://doi.org/10.1016/j.foodchem.2023.137774 Švarc-Gajić, J. Cvetanović, A. Segura-Carretero, A. Linares, I. B. and Mašković, P. 2017. Characterisation of ginger extracts obtained by subcritical water. The Journal of Supercritical Fluids. 123, 92-100. https://doi.org/10.1016/j.supflu.2016.11.010 Vanden, D. A. Vlietinck, A. J. Dey, P. M. and Harborne, J. B. 1991. Methods in plant biochemistry: Screening methods for antibacterial and antiviral agents from higher plants. London: Academic Press. Varmie, E. B. and Thakur, M. 2021. Utilization of citrus processing waste: A review. Pharmaceutical Innovation Journal. 10, 682-697. Zema, D. A. Calabrò, P. S. Folino, A. Tamburino, V. Zappia, G. and Zimbone, S. M. 2018. Valorisation of citrus processing waste: A review. Waste Management. 80, 252-273. https://doi.org/10.1016/j.wasman.2018.09.024 Zhang, J. Wen, C. Zhang, H. Duan, Y. and Ma, H. 2020. Recent advances in the extraction of bioactive compounds with subcritical water: A review. Trends in Food Science & Technology. 95, 183-195. https://doi.org/10.1016/j.tifs.2019.11.018 Zhao, T. Luo, L. Zhang, X. Zhang, W. and Qu, H. 2019. Subcritical water extraction of bioactive compounds from Radix Puerariae and optimization study using response surface methodology. Chemical Engineering Communications. 206(9), 1218-1227. https://doi.org/10.1080/00986445.2018.1555533
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