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Abdul-Wahab Kadhum, Ayaat, Rushdi Abdullah, Ahmed, Mujahid, Arwa. (1401). Increasing levels of serum anti-spike S1-RBD IgG after 120 days of the Pfizer-BioNTech-mRNA second dose vaccination. سامانه مدیریت نشریات علمی, (), -. doi: 10.22092/ari.2022.359934.2517
Ayaat Abdul-Wahab Kadhum; Ahmed Rushdi Abdullah; Arwa Mujahid. "Increasing levels of serum anti-spike S1-RBD IgG after 120 days of the Pfizer-BioNTech-mRNA second dose vaccination". سامانه مدیریت نشریات علمی, , , 1401, -. doi: 10.22092/ari.2022.359934.2517
Abdul-Wahab Kadhum, Ayaat, Rushdi Abdullah, Ahmed, Mujahid, Arwa. (1401). 'Increasing levels of serum anti-spike S1-RBD IgG after 120 days of the Pfizer-BioNTech-mRNA second dose vaccination', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.22092/ari.2022.359934.2517
Abdul-Wahab Kadhum, Ayaat, Rushdi Abdullah, Ahmed, Mujahid, Arwa. Increasing levels of serum anti-spike S1-RBD IgG after 120 days of the Pfizer-BioNTech-mRNA second dose vaccination. سامانه مدیریت نشریات علمی, 1401; (): -. doi: 10.22092/ari.2022.359934.2517

Increasing levels of serum anti-spike S1-RBD IgG after 120 days of the Pfizer-BioNTech-mRNA second dose vaccination

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مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 05 آذر 1401  XML
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.359934.2517
نویسندگان
Ayaat Abdul-Wahab Kadhum email 1؛ Ahmed Rushdi Abdullah1؛ Arwa Mujahid2
1Medical Microbiology Department, Medical College, AL-Iraqia University, Iraq
2Medical Microbiology Dept., Medical College, AL-Nahrain University, Iraq
چکیده
SARS-CoV-2 mRNA vaccines, such as Pfizer-BioNTech, have demonstrated high efficacy; however, there is limited data on the duration of immune responses, besides their relationships to age, gender, BMI and the presence of previous COVID-19 infection. The study's goal is to evaluate SARS COVID-19 Anti-Spike IgG levels after 30 days (1 month) and 120 days (4 months) of the second dose of Pfizer-BioNTech vaccine given to medical students at Al-Iraqia University in Baghdad. This study was performed after the acceptance and approval of the Medical College of Al-Iraqia University and the Iraqi Ministry of Health (MOH). Two groups of students were randomly picked up from Medical College of Al-Iraqia University, who were completely vaccinated by administering two doses of Pfizer-BioNTech/ 0.5 ml for each dose after taking their permission to draw 5 ml of their blood (one group after 1 month and the second group after 4 months of vaccination), which was done in the Higher Education lab inside the Medical College of Al-Iraqia University. It took approximately 4 months to collect the samples (from October 2021 until February 2022), after that serological analysis was done for measuring the SARS-CoV-2 spike protein IgG by using Elabscience /SARS-CoV-2 spike protein IgG ELISA Kit/ USA (+ve <0.06) that was performed in the Higher Education lab of Medical College of Al-Iraqia University. Demographic data were also collected from participants including age, gender, BMI, blood group and the presence of previous Covid-19 infection. For statistical analysis, we used SPSS version 26 and STATISTICA version 12 to input, check, and analyze data. For qualitative variables, standard approaches of frequencies and percentages were used, while for quantitative variables, mean and standard deviation were used. A P value of < 0.05 was considered a significant plasma level of the SARS COVID-19 Anti-Spike IgG.
کلیدواژه‌ها
SARS COVID-19 Anti-Spike IgG؛ Pfizer-BioNTech vaccine؛ Medical students؛ Al-Iraqia University
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تعداد مشاهده مقاله: 43


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