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Gasmi, A, Noor, S, Piscopo, S, Menzel, A. (1401). Toxic Metal –Mediated Neurodegradation: A Focus on Glutathione and GST Gene Variants. سامانه مدیریت نشریات علمی, 77(2), 525-536. doi: 10.22092/ari.2021.356279.1816
A Gasmi; S Noor; S Piscopo; A Menzel. "Toxic Metal –Mediated Neurodegradation: A Focus on Glutathione and GST Gene Variants". سامانه مدیریت نشریات علمی, 77, 2, 1401, 525-536. doi: 10.22092/ari.2021.356279.1816
Gasmi, A, Noor, S, Piscopo, S, Menzel, A. (1401). 'Toxic Metal –Mediated Neurodegradation: A Focus on Glutathione and GST Gene Variants', سامانه مدیریت نشریات علمی, 77(2), pp. 525-536. doi: 10.22092/ari.2021.356279.1816
Gasmi, A, Noor, S, Piscopo, S, Menzel, A. Toxic Metal –Mediated Neurodegradation: A Focus on Glutathione and GST Gene Variants. سامانه مدیریت نشریات علمی, 1401; 77(2): 525-536. doi: 10.22092/ari.2021.356279.1816

Toxic Metal –Mediated Neurodegradation: A Focus on Glutathione and GST Gene Variants

Archives of Razi Institute
مقاله 3، دوره 77، شماره 2، خرداد و تیر 2022، صفحه 525-536    اصل مقاله (527.3 K)
نوع مقاله: Review Article
شناسه دیجیتال (DOI): 10.22092/ari.2021.356279.1816
نویسندگان
A Gasmi* 1؛ S Noor2؛ S Piscopo1، 3؛ A Menzel4
1Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée, Villeurbanne, France
2Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University Multan, Pakistan
3Research and Development Department, Nutri-Logics SA, Weiswampach, Luxembourg
4Laboratoires Réunis, Junglinster, Luxembourg
چکیده
Increasing pieces of evidence have supported those chemicals from industrial, agricultural wastes and organoleptic activities play important role in the development of neurological disorders. The frequency of neurological disorders is increased to a much extent in recent years with the advancements in science and technology. Google Scholar, PubMed, and Scopus databases were selected to search the relevant information by using keywords including “Heavy metals”, “Neurotoxicity”, “Glutathione”, “Glutathione AND Neurodegenerative disorders” etc. Heavy metals are particularly recognized as a major resource of toxicities during the stage of early pregnancy where a fetus gets exposed to them from maternal activities and circulation. As infants have a weak immune system and cannot respond to the specific challenge as faced by the body during mercury, zinc, iron, and cadmium exposure. Daily diet and drinking habits in addition to industrial activities also form a major field of study under investigation. This study aims to investigate the role of these metals in the accumulation of pollutants in the brain, liver, and kidneys hence leading to serious consequences. Moreover, their prevalence in teenagers that are under the age of ten years is being observed that leads them to learn, writing, and intellectual abilities. Males are more affected due to their hormonal differences. The role of the GST gene in the development of cognitive conditions and its phenotypes has been discussed thoroughly in this review. The mutations of GST lead to the accumulation of peroxides and superoxides which exacerbate oxidative damage to cells. Binding of toxic metals to GSH genes and the role of glutathione transferase genes is was demonstrated in this review.
کلیدواژه‌ها
GSH (glutathione)؛ GST (glutathione s-transferase)؛ toxic metals؛ cognitive disease؛ neurodegenerative diseases
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مراجع
  1. Acharya R, Lim C, Joseph P. Heart rate variability analysis using correlation dimension and detrended fluctuation analysis. Itbm-Rbm. 2002;23(6):333-9.
  2. Mihalopoulos C, Vos T, Rapee RM, Pirkis J, Chatterton ML, Lee YC, et al. The population cost‐effectiveness of a parenting intervention designed to prevent anxiety disorders in children. J Child Psychol Psychiatry. 2015;56(9):1026-33.
  3. Galaska R, Makowiec D, Dudkowska A, Koprowski A, Chlebus K, Wdowczyk‐Szulc J, et al. Comparison of wavelet transform modulus maxima and multifractal detrended fluctuation analysis of heart rate in patients with systolic dysfunction of left ventricle. Ann Noninvasive Electrocardiol. 2008;13(2):155-64.
  4. Bolognin S, Messori L, Zatta P. Metal ion physiopathology in neurodegenerative disorders. Neuromolecular Med. 2009;11(4):223-38.
  5. Uversky VN, Li J, Fink AL. Metal-triggered structural transformations, aggregation, and fibrillation of human α-synuclein a possible molecular link between parkinson′ s disease and heavy metal exposure. J Biol Chem. 2001;276(47):44284-96.
  6. Rahimzadeh MR, Rahimzadeh MR, Kazemi S, Moghadamnia A-a. Cadmium toxicity and treatment: An update. Caspian J Intern Med. 2017;8(3):135.
  7. Matés JM, Segura JA, Alonso FJ, Márquez J. Roles of dioxins and heavy metals in cancer and neurological diseases using ROS-mediated mechanisms. Free Radic Biol Med. 2010;49(9):1328-41.
  8. Martinez-Finley EJ, Gavin CE, Aschner M, Gunter TE. Manganese neurotoxicity and the role of reactive oxygen species. Free Radic Biol Med. 2013;62:65-75.
  9. Bell KF, Al-Mubarak B, Martel M-A, McKay S, Wheelan N, Hasel P, et al. Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2. Nat Commun. 2015;6(1):1-15.
  10. Silverman WK, Kurtines WM, Ginsburg GS, Weems CF, Lumpkin PW, Carmichael DH. Treating anxiety disorders in children with group cognitive-behavioral therapy: A randomized clinical trial. J Consult Clin Psychol. 1999;67(6):995.
  11. Barrett PM, Duffy AL, Dadds MR, Rapee RM. Cognitive–behavioral treatment of anxiety disorders in children: Long-term (6-year) follow-up. J Consult Clin Psychol. 2001;69(1):135.
  12. Compton SN, March JS, Brent D, Albano AM, Weersing VR, Curry J. Cognitive-behavioral psychotherapy for anxiety and depressive disorders in children and adolescents: an evidence-based medicine review. J Am Acad Child Adolesc Psychiatry. 2004;43(8):930-59.
  13. Landgren M, Svensson L, Strömland K, Grönlund MA. Prenatal alcohol exposure and neurodevelopmental disorders in children adopted from eastern Europe. Pediatrics. 2010;125(5):1178-85.
  14. Dodd B, Leahy J, Hambly G. Phonological disorders in children: Underlying cognitive deficits. Br J Dev Psychol. 1989;7(1):55-71.
  15. Last CG, Hersen M, Kazdin A, Orvaschel H, Perrin S. Anxiety disorders in children and their families. Arch Gen Psychiatry. 1991;48(10):928-34.
  16. Kendall PC. Treating anxiety disorders in children: results of a randomized clinical trial. J Consult Clin Psychol. 1994;62(1):100.
  17. Chalfant AM, Rapee R, Carroll L. Treating anxiety disorders in children with high functioning autism spectrum disorders: A controlled trial. J Autism Dev Disord. 2007;37(10):1842-57.
  18. Last CG, Perrin S, Hersen M, Kazdin AE. DSM-III-R anxiety disorders in children: Sociodemographic and clinical characteristics. J Am Acad Child Adolesc Psychiatry. 1992;31:1070.
  19. James AC, James G, Cowdrey FA, Soler A, Choke A. Cognitive behavioural therapy for anxiety disorders in children and adolescents. Cochrane Database Syst Rev. 2013;(6).
  20. Currie J, Stabile M. Mental health in childhood and human capital. The problems of disadvantaged youth: An economic perspective: University of Chicago Press; 2007. p. 115-48.
  21. Meadows P, Melhuish E. National evaluation of Sure Start local programmes: An economic perspective. 2011.
  22. Mihalopoulos C, Vos T, Pirkis J, Carter R. The economic analysis of prevention in mental health programs. Annu Rev Clin Psychol. 2011;7:169-201.
  23. Van Steensel FJ, Bögels SM, Perrin S. Anxiety disorders in children and adolescents with autistic spectrum disorders: a meta-analysis. Clin Child Fam Psychol Rev. 2011;14(3):302.
  24. In-Albon T, Schneider S. Psychotherapy of childhood anxiety disorders: A meta-analysis. Psychother Psychosom. 2007;76(1):15-24.
  25. Ipser JC, Stein DJ, Hawkridge S, Hoppe L. Pharmacotherapy for anxiety disorders in children and adolescents. Cochrane Database Syst Rev. 2009;(3).
  26. Wehry AM, Beesdo-Baum K, Hennelly MM, Connolly SD, Strawn JR. Assessment and treatment of anxiety disorders in children and adolescents. Curr Psychiatry Rep. 2015;17(7):52.
  27. Killin LO, Starr JM, Shiue IJ, Russ TC. Environmental risk factors for dementia: a systematic review. BMC Geriatr. 2016;16(1):1-28.
  28. Power MC, Adar SD, Yanosky JD, Weuve J. Exposure to air pollution as a potential contributor to cognitive function, cognitive decline, brain imaging, and dementia: a systematic review of epidemiologic research. Neurotoxicology. 2016;56:235-53.
  29. Castellani RJ, Harris PL, Sayre LM, Fujii J, Taniguchi N, Vitek MP, et al. Active glycation in neurofibrillary pathology of Alzheimer disease: Nε-(carboxymethyl) lysine and hexitol-lysine. Free Radic Biol Med. 2001;31(2):175-80.
  30. Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, et al. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol. 2001;60(8):759-67.
  31. Bonda DJ, Wang X, Perry G, Nunomura A, Tabaton M, Zhu X, et al. Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology. 2010;59(4-5):290-4.
  32. Thulin U, Svirsky L, Serlachius E, Andersson G, Öst L-G. The effect of parent involvement in the treatment of anxiety disorders in children: A meta-analysis. Cogn Behav Ther. 2014;43(3):185-200.
  33. Lebowitz ER, Omer H, Hermes H, Scahill L. Parent training for childhood anxiety disorders: the SPACE program. Cogn Behav Pract. 2014;21(4):456-69.
  34. Chavira DA, Golinelli D, Sherbourne C, Stein MB, Sullivan G, Bystritsky A, et al. Treatment engagement and response to CBT among Latinos with anxiety disorders in primary care. J Consult Clin Psychol. 2014;82(3):392.
  35. Silverman WK, Kurtines WM, Jaccard J, Pina AA. Directionality of change in youth anxiety treatment involving parents: an initial examination. J Consult Clin Psychol. 2009;77(3):474.
  36. Kendall PC, Peterman JS. CBT for adolescents with anxiety: Mature yet still developing. Am J Psychiatry. 2015;172(6):519-30.
  37. Cummings JL. Depression and Parkinson's disease: a review. Am J Psychiatry. 1992.
  38. Limousin P, Krack P, Pollak P, Benazzouz A, Ardouin C, Hoffmann D, et al. Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease. N Engl J Med. 1998;339(16):1105-11.
  39. Deuschl G, Schade-Brittinger C, Krack P, Volkmann J, Schäfer H, Bötzel K, et al. A randomized trial of deep-brain stimulation for Parkinson's disease. N Engl J Med. 2006;355(9):896-908.
  40. Mallet L, Mesnage V, Houeto J-L, Pelissolo A, Yelnik J, Behar C, et al. Compulsions, Parkinson's disease, and stimulation. Lancet. 2002;360(9342):1302-4.
  41. Follett KA, Weaver FM, Stern M, Hur K, Harris CL, Luo P, et al. Pallidal versus subthalamic deep-brain stimulation for Parkinson's disease. N Engl J Med. 2010;362(22):2077-91.
  1. Houeto J, Mesnage V, Mallet L, Pillon B, Gargiulo M, Du Moncel ST, et al. Behavioural disorders, Parkinson's disease and subthalamic stimulation. J Neurol Neurosurg Psychiatry. 2002;72(6):701-7.
  2. Krack P, Pollak P, Limousin P, Hoffmann D, Xie J, Benazzouz A, et al. Subthalamic nucleus or internal pallidal stimulation in young onset Parkinson's disease. Brain. 1998;121(3):451-7.
  3. Thaut MH, McIntosh GC, Rice RR, Miller RA, Rathbun J, Brault J. Rhythmic auditory stimulation in gait training for Parkinson's disease patients. Mov Disord. 1996;11(2):193-200.
  4. Løvås K, Husebye ES. High prevalence and increasing incidence of Addison's disease in western Norway. Clin Endocrinol. 2002;56(6):787-91.
  5. Soule S. Addison's disease in Africa—a teaching hospital experience. Clin Endocrinol. 1999;50(1):115-20.
  6. Jódar E, Valdepeñas MPR, Martinez G, Jara A, Hawkins F. Long-term follow-up of bone mineral density in Addison's disease. Clin Endocrinol. 2003;58(5):617-20.
  7. Masliah E, Ellis RJ, Mallory M, Heaton RK, Marcotte TD, Nelson JA, et al. Dendritic injury is a pathological substrate for human immunodeficiency virus—related cognitive disorders. Ann Neurol. 1997;42(6):963-72.
  8. Wiley JC, Pettan-Brewer C, Ladiges WC. Phenylbutyric acid reduces amyloid plaques and rescues cognitive behavior in AD transgenic mice. Aging Cell. 2011;10(3):418-28.
  9. Caballol N, Martí MJ, Tolosa E. Cognitive dysfunction and dementia in Parkinson disease. Mov Disord. 2007;22(17):358-66.
  10. Hock C, Golombowski S, Naser W, MüLler-Spahn F. Increased levels of τ protein in cerebrospinal fluid of patients with alzheimer's disease—correlation with degree of cognitive impairment. Ann Neurol. 1995;37(3):414-5.
  11. Wiley CA, Achim C. Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome. Ann Neurol. 1994;36(4):673-6.
  12. Finkel S. Introduction to behavioural and psychological symptoms of dementia (BPSD). Int J Geriatr Psychiatry. 2000;15(1):2-4.
  13. Hepburn KW, Tornatore J, Center B, Ostwald SW. Dementia Family Caregiver Training: Affecting Beliefs About Caregiving and Caregiver Outcomes. J Am Geriatr Soc. 2001;49(4):450-7.
  1. Bathgate D, Snowden JS, Varma A, Blackshaw A, Neary D. Behaviour in frontotemporal dementia, Alzheimer's disease and vascular dementia. Acta Neurol Scand. 2001;103(6):367-78.
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