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A Comprehensive Diagnostic Evaluation of Feline (Felis catus) Cholangiohepatitis: Insights from X-ray, Ultrasonography, and Hematology | ||
| Archives of Razi Institute | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 23 آبان 1405 اصل مقاله (696.74 K) | ||
| نوع مقاله: Case Study | ||
| شناسه دیجیتال (DOI): 10.66224/ari.2026.372922.4149 | ||
| نویسندگان | ||
| Ratna - Widyawati* 1؛ Junianto Wika Adi Pratama2؛ Dewi - Larasati3؛ Firman - Supriadiansyah4؛ Miandi - Umniyati4؛ Reyda Maarif Wahyu Saputro5 | ||
| 1Department of Veterinary Clinic, Veterinary Surgery and Radiology section | ||
| 2Doctoral Program in Veterinary Science, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia. | ||
| 3Veterinary Professional Education Students, Faculty of Veterinary Medicine, Universitas Wijaya Kusuma Surabaya | ||
| 4Veterinary Professional Education Students, Veterinary Surgery and Radiography Laboratory of Veterinary Medicine Faculty, Universitas Wijaya Kusuma Surabaya,Surabaya, Indonesia | ||
| 5Veterinary Professional Education Students, Veterinary Surgery and Radiography Laboratory of Veterinary Medicine Faculty, Universitas Wijaya Kusuma Surabaya,Surabaya, Indonesia. | ||
| چکیده | ||
| Feline cholangiohepatitis is a significant inflammatory hepatobiliary disease causing major morbidity in cats. Its clinical relevance is underscored by substantial diagnostic challenges, primarily attributable to nonspecific clinical manifestations like jaundice, anorexia, and lethargy. Furthermore, definitive diagnosis necessitates invasive procedures, including hepatic biopsy, making noninvasive evaluation crucial. A two-year-old intact female domestic cat, weighing exactly 3 kg, was presented for veterinary evaluation due to jaundice, severe lethargy, and complete anorexia. Based on initial clinical assessment, a presumptive diagnosis of cholangiohepatitis was considered, prompting comprehensive diagnostic investigation. The diagnostic evaluation revealed significant abnormalities on imaging and biochemical tests. Abdominal radiography demonstrated marked hepatomegaly, while ultrasonography highlighted gallbladder dilation and marked wall thickening. Biochemical profiling also indicated severe hepatic and biliary involvement, with markedly elevated serum aspartate aminotransferase, alanine aminotransferase, and gamma glutamyl transferase.Diagnostic imaging revealed significant gallbladder enlargement, indicative of severe and acute biliary inflammation and concurrent hepatic involvement. Collectively, these imaging and biochemical abnormalities indicated severe hepatobiliary inflammation, strongly supporting a presumptive clinical diagnosis of cholangiohepatitis. This clinical case illustrates the complementary diagnostic benefit of combining abdominal radiography, ultrasonography, and serum biochemical testing when assessing feline hepatobiliary disease. Here, integrated radiographic findings of hepatomegaly, ultrasonographic abnormalities, and pronounced biochemical increases substantiated a clinical diagnosis of cholangiohepatitis. These findings highlight the necessity of a multimodal diagnostic strategy to accurately define the degree of hepatic and biliary involvement, offering a dependable basis for decision-making in comparable feline cases. | ||
| کلیدواژه‌ها | ||
| Cholangiohepatitis؛ Feline؛ Hepatobiliary؛ Prognosis؛ Therapy | ||
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