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Pathological features of Squamous Cell Carcinoma (SCC) in domestic animals: Retrospective study of 19 cases | ||
| Archives of Razi Institute | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 12 مهر 1405 اصل مقاله (968.89 K) | ||
| نوع مقاله: Case Study | ||
| شناسه دیجیتال (DOI): 10.66224/ari.2026.372567.4089 | ||
| نویسندگان | ||
| Farhang Sasani1؛ ِDiba Golchin1؛ mobina farrokhnia hamedani* 2؛ Mir Sepehr Pedram3؛ Mohammad Mehdi Dehghan3 | ||
| 1Department of Pathology and Clinical pathology, University of Tehran, Tehran, Iran. | ||
| 2دپارتمان پاتولوژی و کلینیکال پاتولوژی، دانشگاه تهران، تهران، ایران. | ||
| 3Department of Surgury and Radiology, University of Tehran, Tehran, Iran. | ||
| چکیده | ||
| Squamous cell carcinoma (SCC) is one of the most frequently diagnosed cutaneous malignancies in veterinary medicine, with ultraviolet (UV) radiation recognized as the principal etiological factor. Although SCC generally has a favorable prognosis, an accurate diagnosis is essential for selecting the most appropriate therapeutic strategy. This retrospective study evaluated 19 cases of SCC diagnosed between 2013 and 2025. Sex information was available for 16 animals, including 10 female dogs, 4 male dogs, and 2 female cats. The affected animals represented various breeds, including Terrier, German Shepherd, Spitz, Spitz–Terrier crossbreeds, and mixed-breed dogs. The tumors were located in the trunk, tail, inguinal region, mammary glands, nostrils, nasal planum, vagina, submandibular region, oral cavity, neck, perineum, elbow, and frontal region. Histopathological grading identified seven Grade I, five Grade II, and four Grade III SCCs. In addition, three cases were diagnosed as adenosquamous carcinoma, a histological variant of SCC. Histopathological examination revealed a broad spectrum of microscopic changes, including hyperkeratosis, parakeratosis, acanthosis, epithelial dysplasia, keratin pearl formation, lymphoplasmacytic infiltration, cellular pleomorphism, and lymphatic invasion. | ||
| کلیدواژه‌ها | ||
| oncology؛ surgical pathology؛ histopathology؛ adenosquamous carcinoma؛ carcinoma in situ | ||
| عنوان مقاله [English] | ||
| بررسی ویژگی های پاتولوژیک کارسینوم سلول سنگ فرشی در حیوانات اهلی: مطالعه ی گذشته نگر 19 مورد | ||
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آمار تعداد مشاهده مقاله: 42 تعداد دریافت فایل اصل مقاله: 41 |
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