اخبار و اعلانات

 آمار

تعداد نشریات282
تعداد نشریات سازمان80
تعداد شماره‌ها3,251
تعداد مقالات35,918
تعداد مشاهده مقاله54,585,044
تعداد دریافت فایل اصل مقاله93,700,306
Sadeghi, Zahra, Kilinc, Hilal, Darrodi, Hadi, Hosseini, Seyed Hamzeh. (1405). Phytochemical Characterization and Antibacterial assessment of Essential oils Derived from Teucrium stocksianum Boiss. and Selected Salvia Species. سامانه مدیریت نشریات علمی, 15(4), 505-511. doi: 10.22034/jmpb.2026.371878.2128
Zahra Sadeghi; Hilal Kilinc; Hadi Darrodi; Seyed Hamzeh Hosseini. "Phytochemical Characterization and Antibacterial assessment of Essential oils Derived from Teucrium stocksianum Boiss. and Selected Salvia Species". سامانه مدیریت نشریات علمی, 15, 4, 1405, 505-511. doi: 10.22034/jmpb.2026.371878.2128
Sadeghi, Zahra, Kilinc, Hilal, Darrodi, Hadi, Hosseini, Seyed Hamzeh. (1405). 'Phytochemical Characterization and Antibacterial assessment of Essential oils Derived from Teucrium stocksianum Boiss. and Selected Salvia Species', سامانه مدیریت نشریات علمی, 15(4), pp. 505-511. doi: 10.22034/jmpb.2026.371878.2128
Sadeghi, Zahra, Kilinc, Hilal, Darrodi, Hadi, Hosseini, Seyed Hamzeh. Phytochemical Characterization and Antibacterial assessment of Essential oils Derived from Teucrium stocksianum Boiss. and Selected Salvia Species. سامانه مدیریت نشریات علمی, 1405; 15(4): 505-511. doi: 10.22034/jmpb.2026.371878.2128

Phytochemical Characterization and Antibacterial assessment of Essential oils Derived from Teucrium stocksianum Boiss. and Selected Salvia Species

Journal of Medicinal plants and By-products
مقاله 11، دوره 15، شماره 4، مهر و آبان 2026، صفحه 505-511    اصل مقاله (593.14 K)
نوع مقاله: Research Article
شناسه دیجیتال (DOI): 10.22034/jmpb.2026.371878.2128
نویسندگان
Zahra Sadeghi* 1؛ Hilal Kilinc2؛ Hadi Darrodi3؛ Seyed Hamzeh Hosseini4
1Department of Production and Utilization of Medicinal Plants, Faculty of Agriculture, University of Saravan, Saravan, Iran
2Dokuz Eylul University Engineering Faculty Department of Geological Engineering, Izmir, Turkiye
3Forest and Rangelands Research Department, Baluchestan Agricultural and Natural Resources Research and Education Center, Iranshahr, Iran
4Department of Biology, Faculty of Science, University of Jiroft, Jiroft, Iran
چکیده
Species belonging to the genera Teucrium and Salvia (Lamiaceae) are widely recognized in ethnomedicine, particularly in the Baluchestan region, as important medicinal plants used in the treatment of ailments such as colds and gastrointestinal disorders, largely attributed to their terpene-rich essential oils (EOs). The aim of this study was to characterize the chemical composition and evaluate the antimicrobial activity of EOs obtained from selected Salvia species and Teucrium stocksianum. In the present study, EOs obtained from Teucrium stocksianum Boiss, Salvia artemisioides Boiss, Salvia abrotanoides Karel., and Salvia yangii Benth., collected from the Baluchestan region of Iran, were chemically characterized and evaluated for their antimicrobial activity. The oils were isolated by hydrodistillation and analyzed using gas chromatography–mass spectrometry (GC–MS). Antimicrobial activity was assessed by the microbroth dilution method against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Bacillus subtilis, and expressed as minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values. The EO yield was 0.45% for T. stocksianum and ranged from 0.8% to 1.35% for the Salvia species. GC–MS analysis revealed that α-pinene (36.83%) and β-pinene (13.39%) were the major constituents of T. stocksianum oil, while 1,8-cineole (31.13%) was the predominant compound in S. yangii. Among the tested samples, the EOs of T. stocksianum and S. yangii exhibited notable antibacterial activity, particularly against E. coli, S. aureus, and B. subtilis, with inhibitory effects observed at concentrations below 20 mg/ml. Importantly, the EO of T. stocksianum, rich in monoterpenes such as α- and β-pinene, demonstrated strong antibacterial potential, with low MIC values against B. subtilis (0.5 ± 0.3 mg/ml) and S. aureus (2 ± 0.8 mg/ml). In contrast, the EOs of S. abrotanoides and S. artemisioides showed limited antimicrobial activity. These findings suggest that the EO of T. stocksianum is a promising natural antimicrobial agent, supporting its ethnomedicinal use and highlighting its potential applications in the development of plant-based therapeutic and preservative agents; however, further in vivo studies are required to confirm its efficacy and safety.
کلیدواژه‌ها
Lamiaceae؛ Ssential oils؛ Secondary metabolites؛ Antimicrobial activity
مراجع
  1. Kubitzki K. The families and genera of vascular plants, flowering plants. Eudicots: Malpighiales, Springer-Berlin, Heidelberg. 2014.
  2. Askari S.F, Avan R., Tayarani-Najaran Z., Sahebkar A., Eghbali S. Iranian Salvia species: A phytochemical and pharmacological update. Phytochemistry. 2021; 183:112619.
  3. Golfakhrabadi F., Yousefbeyk F., Mirnezami T., Laghaei P., Hajimahmoodi M. Antioxidant and antiacetylcholinesterase activity of Teucrium hyrcanicum. Pharmacognosy Research. 2015;7:15-19
  4. Sadeghi Z., Farimani M.M., Khorrami F., Abdollahi V. Insecticidal and oviposition deterrent effects of pure and combined essential oils of Salvia subg. Perovskia species against Phthorimaea operculella. South African Journal of Botany. 2022;151:126-132.
  5. Sadeghi Z., Cerulli A., Marzocco S., Farimani M.M., Masullo M. Anti-inflammatory activity of tanshinone-related diterpenes from Perovskia artemisioides Roots. Journal of Natural Products. 2023;86(4):812-821.
  6. Sadeghi Z., Masullo M., Cerulli A., Nazzaro F., Farimani M.M. Terpenoid constituents of Perovskia artemisioides aerial parts with inhibitory effects on bacterial biofilm growth. Journal of Natural Products. 2020; 84(1):26-36.
  7. Tabefam M., Farimani M.M., Danton O., Ramseyer J., Nejad Ebrahimi S. Antiprotozoal isoprenoids from Salvia hydrangea. Journal of Natural Products. 2018;81(12):2682-2691.
  8. Yazdi F.T., Behbahani B.A. Antimicrobial effect of the aqueous and ethanolic Teucrium polium L. extracts on gram-positive and gram-negative bacteria “in vitro”. Archives of Advances in Biosciences. 2013;4,4.
  9. Imran M., Irfan A., Mehmood R., Sumrra S.H., Assiri M.A. Phytochemical, pharmacological and in silico studies on Teucrium stocksianum Bioss. Journal of King Saud University Science. 2022;34(4):101969.
  10. Sadrizah N., Khezri S., Dehghan P., Mahmoudi R. Antibacterial Effect of Teucrium polium Essential oil and Lactobacillus casei Probiotic on Escherichia coli O157:H7 in Kishk. Applied Food Biotechnology. 2018;5(3):131-140.
  11. Keykavousi M., Tarzi B.G., Mahmoudi R., Bakhoda H., Kabudari A., Mahalleh S.F.R.P. Study of antibacterial effects of Teucrium polium essential oil on Bacillus cereus in cultural laboratory and commercial soup. Carpathian Journal of Food Science and Technology. 2016,8(2),176-183.
  12. Tabassum N., Aziz A., Ahmad B. Evaluation of pharmacological effect of Teucrium stocksianum extract on angiogenesis using chorioallantoic membrane assay. Bangladesh Journal of Pharmacology. 2016;11(3):621-627.
  13. Shah S.M.M., Sadiq A., Shah S.M.H., Ullah F. Antioxidant, total phenolic contents and antinociceptive potential of Teucrium stocksianum methanolic extract in different animal models. BMC Complementary and Alternative Medicine. 2014;14:1-7.
  14. Shah S.M.M. A possible anti-inflammatory mechanism of ethyl acetate extracts of Teucrium stocksianum Bioss. BMC Complementary and Alternative Medicine. 2015;15:1-6.
  15. Tanira M.O.M., Wasfi I.A., Homsi M.A., Bashir A.K. Toxicological effects of Teucrium stocksianum after acute and chronic administration in rats. Journal of Pharmacy and Pharmacology. 1996;48, (10):1098-1102.
  16. Rasheed R.A., Ali B.H., Bashir A.K. Effect of Teucrium stocksianum on paracetamol-induced hepatotoxicity in mice. General Pharmacology: The Vascular System. 1995;26(2):297-301.
  17. Sadeghi Z., Yang J., Venditti A., Moridi Farimani M. A review of the phytochemistry, ethnopharmacology and biological activities of Teucrium genus (Germander), Natural Product Research. 2022;36, (21):5647-5664.
  18. Shoeib N.G., Al-Madboly L.A. Sharmin E, Zafar F. Antimicrobial importance of essential oils. Vegetable Oil-Based Polymers and their Surface Applications. Elsevier. 2024;17,259-276.
  19. Method for dilution antimicrobial susceptibility test for bacteria that grow aerobically, Approved standard, 7th ed. M7-A7. National Committee for Clinical Laboratory Standards, Wayne-PA, 2006.
  20. Mojab F., Javidnia K., Yazdani D., Rostaeean A. Essential oil of the aerial parts of Teucrium stocksianum Boiss. subsp. stocksianum (Lamiaceae) from Iran. Journal of Medicinal Plants. 2003;6:49-54.
  21. Yavari A. R. Evaluation of essential oil constituents of different organs from Teucrium stocksianum Boiss. Iranian Journal of Medicinal and Aromatic Plants Research. 2021;37(5):753-765.
  22. Mahmoudi R., Kazeminia M., Kaboudari A. Review on composition and antimicrobial effects of Teucrium (Teucrium polium L.) grown in Iran and comparison with the around the world. J. Babol Univ. Med. Sci. 2017;19(2):54-64.
  23. Shah S.M.M., Ullah F., Shah S.M.H., Zahoor M., Sadiq A. Analysis of chemical constituents and antinociceptive potential of essential oil of Teucrium stocksianum bioss collected from the North West of Pakistan. BMC Complementary and Alternative Medicine. 2012; 12:1-6.
  24. Mahmoudi R. and Nosratpour S. Teucrium polium L. essential oil: phytochemical component and antioxidant properties. International Food Research Journal. 2013;20(4):1697-1701.
  25. Bozzini M.F., Pieracci Y., Ascrizzi R., Najar B., D'Antraccoli M., Ciampi L., Peruzzi L., Turchi B., Pedonese F., Alleva A., Flamini G., Fratini F. Chemical composition and antimicrobial activity against the listeria monocytogenes of essential oils from seven Salvia species. Foods. 2023,12(23):4235.
  26. Maache S., Zbadi L., Ghouizi, A.E. Antioxidant and antimicrobial effects of essential oils from two salvia species with in vitro and in silico analysis targeting 1AJ6 and 1R4U proteins. Sci Rep. 2023;13,14038.
  27. Lahlou Y., Moujabbir S., Aboukhalaf A., Amraoui B.E., Bamhaoud T. Antibacterial activity of essential oils of Salvia officinalis growing in Morocco. Roczniki Państwowego Zakładu Higieny / Annals of the National Institute of Hygiene. 2023;74(4):459-468.
  28. Rhaimi S., Taibi M., Barrahi M., El Hartiti H., Elbouzidi A., Allali A., Ouhssine, M. Molecular docking analysis, chemical composition, and evaluation of antibacterial and insecticidal activity of Salvia officinalis essential oil. Journal of Food Processing and Preservation. 2024;1,9961973.
  29. Shaverdi M., Rafiee Z., Razmjoue D. Antibacterial, antioxidant, and anti-giardia properties of the essential oil, hydroalcoholic extract, and green synthesis of the silver nanoparticles of Salvia mirzayanii plant. Sci Rep. 2024;14,22866.
  30. Al-Hajj N., Bsharat O., Jaradat N. Assessing Salvia dominica L.: from chemical profiling to antioxidant, antimicrobial, anticancer, α-amylase, and α-glycosidase activities of the plant essential oil. Chem. Biol. Technol. Agric. 2025;12,94.
  31. Gherib M., Gordo B., Ziane M. Chemical composition and antimicrobial activity of Teucrium luteum subsp. flavovirens essential oil from Northwestern Algeria. Vegetos. 2023;36,534–541.
  32. Oussama C., Aziz E., Badr Mohamed G., Sara C., Kamal K., Abdelaziz C., Tiskar M. Chemical composition and evaluation of the antibacterial and antifungal activities of pre-rif Teucrium polium essential oil. Research Journal of Pharmacy and Technology. 2022;15(4):1755.
  33. Boukhira S., Balouiri M., Bousta F., Moularat S., Taleb M.S. Antimicrobial activities of essential oil of five plant species from Morocco against some microbial strains. International Journal of Pharmacognosy and Phytochemical Research. 2016;8(11):1901- 1906.
  34. Burt S. Essential oils: their antibacterial properties and potential applications in foods—A review. Journal of Applied Microbiology. 2004;94(2),223–253.
  35. Hyldgaard M., Mygind T., Meyer R. L. Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components. Frontiers in Microbiology. 2012;3,12.
  36. Rahim G., Qureshi R., Hazrat A., Ahmad B., Khan A.A. Phytochemical, antimicrobial, radical scavenging and in-vitro biological activities of Teucrium stocksianum leaves. Journal of the Chilean Chemical Society. 2023;68(1):5748-5754.
  37. Mahboubi M., Kazempour N. The antimicrobial activity of essential oil from Perovskia abrotanoides Karel and its main components. Indian Journal of Pharmaceutical Sciences. 2009;71(3):343.
  38. Schürmann M., Oppel F., Gottschalk M., Büker B., Jantos C.A. The therapeutic effect of 1,8-cineol on pathogenic bacteria species presents in chronic rhinosinusitis. Frontiers in Microbiology. 2019;10:2325.
  39. Hafez Ghoran S., Azadi B., Hussain H. Chemical composition and antimicrobial activities of Perovskia artemisioides Boiss. essential oil. Natural Product Research. 2016;30(17):1997-2001.
  40. Salehi B., Upadhyay S., Orhan I.E., Jugran A.K., Jayaweera S.L.D. Therapeutic potential of α- and β-pinene: a miracle gift of nature. Biomolecules. 2019;9(11):738.
  41. da Silva A.C., Lopes P.M., de Azevedo M.M., Costa D.C., Alviano C.S. Biological activities of alpha-pinene and beta-pinene enantiomers. Molecules. 2012;25,17(6):6305-6316.
آمار
تعداد مشاهده مقاله: 153
تعداد دریافت فایل اصل مقاله: 177


counter
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب