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تاثیر بتاگلوکان دیواره سلولی مخمر نانوایی (ساکارومایسس‌سرویسیه) به صورت خالص و در ترکیب با بنتونیت بر جذب آفلاتوکسین B1 جیره بزهای شیری مهابادی | ||
| علوم دامی | ||
| دوره 39، شماره 151، شهریور 1405، صفحه 117-130 اصل مقاله (1.99 M) | ||
| نوع مقاله: مقاله پژوهشی | ||
| شناسه دیجیتال (DOI): 10.22092/asj.2025.369545.2498 | ||
| نویسندگان | ||
| مونا سلیقه1؛ محمدحسن فتحی نسری* 2؛ مهدی گنج خانلو3؛ محبوبه سرابی جماب4 | ||
| 1دانشجوی دکتری، گروه علوم دامی دانشکده کشاورزی دانشگاه بیرجند | ||
| 2استاد گروه علوم دامی دانشکده کشاورزی دانشگاه بیرجند | ||
| 3استاد گروه علوم دامی پردیس کشاورزی و منابع طبیعی دانشگاه تهران | ||
| 4استاد گروه زیست فناوری مواد غذایی، مؤسسه پژوهشی علوم و صنایع غذایی، مشهد. | ||
| چکیده | ||
| این مطالعه به‌منظور بررسی کاهش انتقال آفلاتوکسینB1خوراک، به شیر بزهای تغذیه شده با بتاگلوکان دیواره سلولی مخمر نانوایی به صورت خالص و در ترکیب با بنتونیت انجام شد. تعداد 18 رأس بز شیری مهابادی با وزن اولیه 93/4±15/47 کیلوگرم به سه گروه آزمایشی با شش تکرار اختصاص یافتند. گروه‌های آزمایشی شامل:1) شاهد (جیره حاوی 25 میکروگرم بر کیلوگرم آفلاتوکسین B1 بر حسب ماده خشک)،2) شاهد + 3 گرم در روز بتاگلوکان و3) شاهد+ 6/0گرم در روز بتاگلوکان + 4/2 گرم در روز بنتونیت تجاری بود. پس از یک هفته سازگاری، همه بزها یک چالش خفیف 14 روزه با آفلاتوکسین B1را تجربه کردند که طی آن مصرف ماده خشک، راندمان مصرف خوراک، تولید و ترکیب شیر، غلظت آفلاتوکسینM1 شیر و فراسنجه‌های خونی آن‌ها ارزیابی شد. نتایج نشان دادند وزن اولیه و نهایی، تولید شیر و ترکیب آن، مصرف ماده خشک و راندمان مصرف خوراک در گروه‌های مختلف مشابه بود. غلظت نیتروژن اوره خون، آلانین ترانس‌آمیناز، آسپارتات ترانس‌آمیناز و آلکالین‌فسفاتاز در گروه‌های مختلف نسبت به گروه‌شاهد تغییر یافت (P< 0.05). همچنین افزودن هردو نوع جاذب سم به جیره بزها، سبب کاهش معنی‌داری در درصد انتقال، غلظت و ترشح آفلاتوکسینM1، نسبت به گروه شاهد شد. به طور کلی، نتایج این مطالعه نشان دادند که ترکیب بتاگلوکان و بنتونیت با نسبت مشخص شده در این تحقیق توانایی جذب آفلاتوکسینB1 را مشابه با بتاگلوکان خالص دارد و می‌تواند غلظت آفلاتوکسینM1 شیر را به یک میزان کاهش دهد؛ بنابراین ترکیب بتاگلوکان و بنتونیت به عنوان یک جاذب مقرون‌به‌صرفه آفلاتوکسینB1 نسبت‌به بتاگلوکان‌خالص در جیره‌دام‌ها قابل‌توصیه است. | ||
| کلیدواژه‌ها | ||
| آفلاتوکسین؛ بتاگلوکان؛ بنتونیت؛ دیواره سلولی مخمر؛ مایکوتوکسین | ||
| عنوان مقاله [English] | ||
| Impact of Bakery Yeast Cell Wall Beta-Glucan (Saccharomyces cerevisiae) and Bentonite on the Adsorption of Aflatoxin B1 of Mahabadi Dairy Goats | ||
| نویسندگان [English] | ||
| سلیقه saligheh1؛ M. H. Fathi Nasari2؛ M. Ganj Khanloo3؛ M. Sarabi-Jamab4 | ||
| 1PhD student, Department of Animal Sciences, Faculty of Agriculture, University of Birjand. | ||
| 2Professor, Department of Animal Sciences, Faculty of Agriculture, University of Birjand. | ||
| 3Department of Animal Sciences, Faculty of Agriculture, University of Tehran. | ||
| 4Professor, Department of Food Biotechnology, Research Institute of Food Science and Technology (RIFST), Mashhad | ||
| چکیده [English] | ||
| This study aimed to investigate the reduction of aflatoxinB1 transfer from feed to milk of goats fed a diet contaminated with aflatoxinB1,by pure baker's yeast cell wall beta-glucan(Saccharomyces cerevisiae)in combination with bentonite.Eighteen Mahabadi dairy goats with an initial weight of47.15±4.93 kg were randomly divided into three experimental groups with six replications.The treatments included:1) control (diet containing 25μg/kg dry matter of feed, aflatoxin B1),2)control +3g/day beta-glucan, and 3)control+0.6 g/day beta-glucan+2.4g/day commercial bentonite. After one week of acclimation, all goats underwent a 14-day mild aflatoxin B1 challenge during which dry matter intake, feed efficiency, milk production and composition, the concentration of aflatoxin M1 in the milk, and blood parameters were evaluated. The results showed that the initial and final weight, milk production and composition,dry matter intake and feed efficiency were similar in different groups The concentration of blood urea nitrogen,alanine transaminase,aspartate transaminase, and alkaline phosphatase, concentration,excretion and percentage of aflatoxin M1 transfer in milk changed in different groups compared to the control group (P<0.05). Also, two groups 2and3 showed a significant decrease in the percentage of transfer, concentration and excretion of aflatoxinM1 compared to the positive control group. In general, the results of this study showed that the combination of beta-glucan and bentonite with the ratio specified in this study has the ability to absorb aflatoxinB1 similar to beta-glucan and can reduce the concentration of aflatoxinM1 in milk to the same extent;Therefore,the combination of beta-glucan and bentonite is recommended as a cost-effective adsorbent of aflatoxinB1 compared to pure beta-glucan in livestock diets. | ||
| کلیدواژه‌ها [English] | ||
| Aflatoxin, Bentonite, Beta-glucan, Mycotoxin, Yeast Cell Wall | ||
| مراجع | ||
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