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Investigation and Comparison of Antimicrobial Effects of Synthetic Zinc Nanoparticles in Nannorrhops ritchiana L against on Gram-negative and Gram-positive Bacteria | ||
| Journal of Medicinal plants and By-products | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 16 خرداد 1405 اصل مقاله (832.72 K) | ||
| نوع مقاله: Research Article | ||
| شناسه دیجیتال (DOI): 10.22034/jmpb.2026.370562.2041 | ||
| نویسندگان | ||
| Khadijeh Saravani1؛ Leli Rezaie Kahkhaie2؛ Hossein Poormasoumi3؛ Solyman Saravani* 4؛ Maryam Beigomi* 5 | ||
| 1Forensic Medicine and Toxicology, Faculty of Medicine, Zabol University of Medical Sciences, Zabol, Iran | ||
| 2Zabol University of Medical Sciences, Zabol, Iran | ||
| 3Department of Infectious Diseases, School of Medicine, Zabol University of Medical Sciences, Zabol, Iran | ||
| 4Department of community medicine, School of Medicine, Zabol university of Medical Sciences | ||
| 5Department of Food Science and Technology, Zahedan University of Medical Sciences, Zahedan, Iran | ||
| چکیده | ||
| Due to their unique physicochemical properties, the production and application of nanomaterials have significantly increased across biomedical, environmental, and pharmaceutical fields. Ethanoic extract of Nannorrhops ritchiana was prepared by the maceration method. For the synthesis of zinc nanoparticles, the aqueous extract of Nannorrhops ritchiana is combined with 0.1 M zinc sulfate solution to form zinc nanoparticles. The average diameter of the nanoparticles is measured by X-ray diffraction and scanning electron microscopy (SEM). The antimicrobial activity of the synthesized zinc nanoparticles was assessed against standard bacterial strains using the microdilution method, and the diameter of the inhibitory zone and the minimum inhibitory concentration against the bacterial strains were determined. The results revealed that at a concentration of nanoparticles Nannorrhops ritchiana 1024 µg/mL, the largest inhibition zones were observed against Proteus mirabilis (25 mm) and Streptococcus mutans (15 mm). At 256 µg/mL, no inhibition zone was detected against Streptococcus pyogenes, while Proteus mirabilis showed a 17 mm zone of inhibition, and ethanol extract showed that the largest diameter of the inhibitory zone was at a concentration of 1024 µg/mL against Proteus mirabilis bacteria (10 mm), while the lowest inhibition was against Bacillus cereus and Streptococcus pyogenes bacteria. These findings suggest that zinc nanoparticles synthesized from Nannorrhops ritchiana exhibit strong antibacterial activity against human pathogens, even under particulate matter–contaminated environmental conditions. | ||
| کلیدواژهها | ||
| Zinc nanoparticles؛ Nannorrhops ritchiana؛ Gram positive bacteria؛ Gram negative؛ Ethanol extract | ||
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آمار تعداد مشاهده مقاله: 152 تعداد دریافت فایل اصل مقاله: 85 |
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