اخبار و اعلانات

 آمار

تعداد نشریات282
تعداد نشریات سازمان80
تعداد شماره‌ها3,262
تعداد مقالات36,058
تعداد مشاهده مقاله55,185,806
تعداد دریافت فایل اصل مقاله94,184,850
Nsaif, Reem. (1405). Comparative study between Aloe vera (L.) Burm.f. Extract Mouth Rinse and Chlorhexidine Mouth Rinse in Preventing Biofilm Growth on Titanium Dental Implants. سامانه مدیریت نشریات علمی, 15(6), 684-689. doi: 10.22034/jmpb.2026.372362.2156
Reem Nsaif. "Comparative study between Aloe vera (L.) Burm.f. Extract Mouth Rinse and Chlorhexidine Mouth Rinse in Preventing Biofilm Growth on Titanium Dental Implants". سامانه مدیریت نشریات علمی, 15, 6, 1405, 684-689. doi: 10.22034/jmpb.2026.372362.2156
Nsaif, Reem. (1405). 'Comparative study between Aloe vera (L.) Burm.f. Extract Mouth Rinse and Chlorhexidine Mouth Rinse in Preventing Biofilm Growth on Titanium Dental Implants', سامانه مدیریت نشریات علمی, 15(6), pp. 684-689. doi: 10.22034/jmpb.2026.372362.2156
Nsaif, Reem. Comparative study between Aloe vera (L.) Burm.f. Extract Mouth Rinse and Chlorhexidine Mouth Rinse in Preventing Biofilm Growth on Titanium Dental Implants. سامانه مدیریت نشریات علمی, 1405; 15(6): 684-689. doi: 10.22034/jmpb.2026.372362.2156

Comparative study between Aloe vera (L.) Burm.f. Extract Mouth Rinse and Chlorhexidine Mouth Rinse in Preventing Biofilm Growth on Titanium Dental Implants

Journal of Medicinal plants and By-products
مقاله 8، دوره 15، شماره 6، بهمن و اسفند 2026، صفحه 684-689    اصل مقاله (2.23 M)
نوع مقاله: Research Article
شناسه دیجیتال (DOI): 10.22034/jmpb.2026.372362.2156
نویسنده
Reem Nsaif*
Al-Esraa University, Baghdad, Iraq
چکیده
The primary concern regarding peri-implant infections is the growth of biofilm on dental implant abutments. It is believed that using antimicrobial mouthwash may reduce biofilm development and subsequent infections. This study aimed to assess the anti-biofilm properties of Aloe vera extract (AVE) against Streptococcus mutans biofilm cultivated on titanium dental implant discs. The experiment utilized medical-grade titanium dental implant discs measuring 15 mm in diameter. To determine the phytochemical profile of AVE, its constituents were analyzed using gas chromatography-mass spectrometry (GC-MS), identifying various bioactive compounds, including anthraquinones, flavonoids, and saponins, known for their antimicrobial effects.he study involved sampling St. mutans from a healing abutment on a freshly placed dental implant and culturing it on titanium discs in vitro. The titanium specimens were inoculated with bacteria and incubated at 37 °C for 24 hours, after which they were treated with chlorhexidine gluconate (CHX) (n = 5) or AVE (n = 5). Antibacterial activity tests revealed that both AVE and CHX significantly inhibited bacterial growth compared to the negative control. The levels of lactate and turbidity were notably lower in both treatment groups than in the control (p< 0.05). In the antibiofilm testing, there was a statistically significant reduction in turbidity for biofilms in both treatment groups. Scanning electron microscope (SEM) images showed minimal bacterial adherence to the titanium discs in the treatment groups, while confluent and integrated biofilms were observed on the discs in the control groups. These results suggest that A. vera extract possesses significant antimicrobial and antibiofilm properties against Streptococcus mutans and could be clinically utilized as a natural mouthwash alternative.
کلیدواژه‌ها
Aloe vera extract؛ Antibiofilm؛ Natural mouthwash؛ Streptococcus mutans؛ Titanium dental implant
مراجع
  1. Herrera D., Tonetti M.S., Chapple I., Kebschull M., Papapanou P.N., Sculean A., Abusleme L., Aimetti M., Belibasakis G., Blanco J. Consensus report of the 20th European workshop on periodontology: contemporary and emerging technologies in periodontal diagnosis. Journal of Clinical Periodontology. 2025; 52: 4-33.
  2. Roos‐Jansåker A.M., Renvert H., Lindahl C., Renvert S. Nine‐to fourteen‐year follow‐up of implant treatment. Part III: factors associated with peri‐implant lesions. Journal of Clinical Periodontology. 2006; 33(4): 296-301.
  3. Heitz‐Mayfield L.J., Salvi G.E. Peri‐implant mucositis. Journal of Clinical Periodontology. 2018; 45: S237-S245.
  4. Salvi G.E., Aglietta M., Eick S., Sculean A., Lang N.P., Ramseier C.A. Reversibility of experimental peri‐implant mucositis compared with experimental gingivitis in humans. Clinical Oral Implants Research. 2012; 23(2): 182-190.
  5. Ramanauskaite A., Fretwurst T., Schwarz F. Efficacy of alternative or adjunctive measures to conventional non-surgical and surgical treatment of peri-implant mucositis and peri-implantitis: A systematic review and meta-analysis. International Journal of Implant Dentistry. 2021; 7(1): 112.
  6. Wohlfahrt J.C., Aass A.M., Koldsland O.C. Treatment of peri‐implant mucositis with a chitosan brush—A pilot randomized clinical trial. International Journal of Dental Hygiene. 2019; 17(2): 170-176.
  7. Mariani G.M., Ercoli E., Guzzi N., Bongiovanni L., Bianco L., Romano F., Aimetti M. One-year clinical outcomes following non-surgical treatment of peri-implant mucositis with adjunctive diode laser application. Minerva Stomatologica. 2020; 69(5): 269-277.
  8. Iorio-Siciliano V., Blasi A., Stratul S.-I., Ramaglia L., Sculean A., Salvi G.E., Rusu D. Anti-infective therapy of peri-implant mucositis with adjunctive delivery of a sodium hypochlorite gel: a 6-month randomized triple-blind controlled clinical trial. Clinical Oral Investigations. 2020; 24(6): 1971-1979.
  9. Koban I., Holtfreter B., Hübner N.O., Matthes R., Sietmann R., Kindel E., Weltmann K.D., Welk A., Kramer A., Kocher T. Antimicrobial efficacy of non‐thermal plasma in comparison to chlorhexidine against dental biofilms on titanium discs in vitro–proof of principle experiment. Journal of Clinical Periodontology. 2011; 38(10): 956-965.
  10. Alqahtani A., Mohamed A.A., Ahmad I., Alraey Y., Asiri M., Kopel J., Alshahrani M.M. Pomegranate peel extract is an effective agent against MDR bacteria. Cellular and Molecular Biology. 2023; 69(5): 6-11.
  11. Gupta D., Nayan S., Tippanawar H.K., Patil G.I., Jain A., Momin R.K., Gupta R.K. Are herbal mouthwash efficacious over chlorhexidine on the dental plaque? Pharmacognosy Research. 2015; 7(3): 277.
  12. Poorkazemi D., Malekzadeh S.A., Nasiri P., Aarabi M., Mehrani S.J. Evaluation of Aloe vera as a natural pharmaceutic in mouthwashes: A Narrative Review. 2022.
  13. Al‐Maweri S.A., Nassani M.Z., Alaizari N., Kalakonda B., Al‐Shamiri H.M., Alhajj M.N., Al‐Soneidar W.A., Alahmary A.W. Efficacy of Aloe vera mouthwash versus chlorhexidine on plaque and gingivitis: A systematic review. International Journal of Dental Hygiene. 2020; 18(1): 44-51.
  14. Boyapati R., Peeta J., Dhulipalla R., Kolaparthy L., Adurty C., Cheruvu R.N.S. Comparative evaluation of the efficacy of probiotic, Aloe vera, povidine-iodine, and chlorhexidine mouthwashes in the treatment of gingival inflammation: A randomized controlled trial. Dental and Medical Problems. 2024; 61(2): 181-189.
  15. Naghsh N., Moghareabed A., Nematnejad M., Yaghini J., Sadeghi S.M. A comparative evaluation of the antimicrobial effect of chamomile, Aloe vera-green tea, and chlorhexidine mouthwashes on some oral bacterial species. Dental Research Journal. 2023; 20(1): 70.
  16. de Sousa Eduardo L., Farias T.C., Ferreira S.B., Ferreira P.B., Lima Z.N., Ferreira S.B. Antibacterial activity and time-kill kinetics of positive enantiomer of α-pinene against strains of Staphylococcus aureus and Escherichia coli. Current Topics in Medicinal Chemistry. 2018; 18(11): 917-924.
  17. Jadhav A.N., Rathod S.R., Kolte A.P., Bawankar P.V. Effect of Aloe vera as a local drug delivery agent in the management of periodontal diseases: a systematic review and meta-analysis. Journal of Indian Society of Periodontology. 2021; 25(5): 372-378.
  18. Abu-Seida A.M., Seif H. Aloe vera in dentistry: current status and future prospects. International Arab Journal of Dentistry. 2023; 14(2): 18.
  19. Hosseini F., Adlgostar A., Sharifnia F. Antibacterial activity of Pistacia atlantica extracts on Streptococcus mutans biofilm. International Research Journal Biological Science. 2013; 2(2): 1-7.
  20. Zebarjadi A. Introduction of chia (Salvia hispanica L.) as an important oil-medicinal plant. Agrotechniques in Industrial Crops. 2022.
  21. Chaghakaboodi Z., Nasiri J., Farahani S. Fumigation Toxicity of the Essential Oils of Ferula persica against Tribolium castaneum and Ephestia kuehniella. 2022.
  22. Ganjali S., Khajeh H., Gholami Z., Jomeh-ghasemabadi Z., Fazeli-Nasab B. Evaluation of Dormancy Failure Datura stramonium Plant Seeds under the Influence of Different Treatments. Agrotechniques in Industrial Crops. 2022; 2(1): 32-41.
  23. Ghamarnia H., Palash M., Dousti B. Camelina zoning for different climate conditions in Kurdistan Province. Agrotechniques in Industrial Crops. 2022; 2(1): 49-56.
  24. Muhialdin A.J., Alamri Z.Z., Hussein A.M., Faraj R.K., Taha Z.B., Hussein M.M., Mojarradgandoukmolla S. Gastro-protective and therapeutic effect of Punica granatum against stomach ulcer caused by Helicobacter Pylori. Cellular and Molecular Biology. 2023; 69(1): 48-53.
آمار
تعداد مشاهده مقاله: 367
تعداد دریافت فایل اصل مقاله: 251


counter
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب