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بهینه‌سازی فرآیند استخراج مواد موثره تفاله پرتقال با استفاده از آب تحت بحرانی | ||
| تحقیقات مهندسی صنایع غذایی | ||
| مقاله 1، دوره 25، شماره 1 - شماره پیاپی 80، فروردین 1405، صفحه 1-20 اصل مقاله (1.31 M) | ||
| نوع مقاله: مقاله پژوهشی | ||
| شناسه دیجیتال (DOI): 10.22092/fooder.2026.368574.1416 | ||
| نویسندگان | ||
| نیلوفر قاسمپور1؛ امیرحسین الهامی راد2؛ مجید جوانمرد* 3؛ الهام آذرپژوه* 4؛ محمد آرمین5 | ||
| 1گروه علوم و صنایع غذایی، واحد سبزوار، دانشگاه آزاد اسلامی، سبزوار، ایران | ||
| 2دانشگاه ازاد اسلامی واحد سبزوار | ||
| 3lمدیر گروه صنایع غذایی و تبدیلی - سازمان پژوهش های ایران | ||
| 4دانشیار پژوهش بخش تحقیقات فنی و مهندسی کشاورزی، مرکز تحقیقات و آموزش کشاورزی و منابع طبیعی استان خراسان رضوی، سازمان تحقیقات، | ||
| 5عضو هیات علمی دانشگاه آزاد اسلامی واحد سبزوار | ||
| چکیده | ||
| پژوهش حاضر با هدف استفادۀ بهینه از تفالۀ پرتقال به‌عنوان پسماند کشاورزی و کارخانههای تولید آب پرتقال و استخراج ترکیبات زیستفعال (ضداکسایشی و ضدمیکروبی) اجرا گردید. به‌منظور بهینه سازی راندمان استخراج، میزان ترکیبات فنلی و فعالیت آنتی اکسیدانی عصاره استخراج‌شده با آب تحت بحرانی از طرح مرکزی وجه‌محور Face-Centered CCD استفاده شد. دمای استخراج (120، 140 و 160 درجه سلسیوس) و زمان استخراج (20، 30 و 40 دقیقه) به‌عنوان متغیرهای استخراج ترکیبات زیست فعال در نظر گرفته شدند. بر اساس مدل های حاصل، شرایط بهینۀ استخراج شامل دمای 142.87درجة سلسیوس و زمان 39.97 دقیقه تعیین شد. در این شرایط، بازده استخراج 13.94 درصد، میزان ترکیبات فنلی کل454.80میلی‌گرم گالیک اسید در صد گرم و قدرت مهار رادیکال آزاد 51.78 درصد به دست آمد. استخراج در نقطۀ بهینه نتایج به‌دست آمده را تأیید کرد. علاوه بر این، عصارة استخراج‌شده دارای خواص ضدمیکروبی مؤثر بود، به‌طوری‌که حداقل غلظت بازدارندگی عصاره علیه قارچ پنی‌سیلیوم سیترینیوم و آسپرژیلوس نایجر به ترتیب 10 و 5 درصد بود، درحالی‌که این مقدار برای داروی فلوکنازول 1 درصد گزارش شده است. این مطالعه کارایی بالای فرآیند آب تحت بحرانی را در استخراج ترکیبات زیستفعال از ضایعات کشاورزی به اثبات رساند و آن را به‌عنوان روشی سازگار با محیط‌زیست و مؤثر برای تولید ترکیبات ارزشمند معرفی کرد. | ||
| کلیدواژه‌ها | ||
| تفاله پرتقال؛ آب تحت بحرانی؛ ترکیبات فنلی؛ ضدمیکروبی | ||
| عنوان مقاله [English] | ||
| Optimization of the Extraction Process of Bioactive Compounds from Orange Peel Waste Using Subcritical Water | ||
| نویسندگان [English] | ||
| niloofar Ghasempour1؛ Amir hussein Elhami Rad2؛ MAJID javanmardi3؛ Elham Azarpazhooh4؛ Mohammad Armin5 | ||
| 1Group of Food Science and Industry, Ehad Sabzvar, University of Azad Islami, Sabzvar, Iran | ||
| 2University of Azad Islami One Green Garden | ||
| 3Director of Food Industry and Processing Department - Iran Research Organization | ||
| 4Associate Professor Department of Agricultural Engineering Institute, Khorasan Razavi Agricultural and Natural Resources Research and Education Center, AREEO, Address: P.O.Box 91735-488, Mashhad-Iran http://kanrrc.areo.ir Tel&Fax(work) | ||
| 5Member of the academic staff of Islamic Azad University, Sabzevar branch | ||
| چکیده [English] | ||
| This study aimed to optimize the extraction of bioactive compounds (antioxidant and antimicrobial) from orange pomace, a byproduct of orange juice production. A Face-Centered CCD design was employed to maximize extraction yield, total phenolic content, and antioxidant activity using subcritical water. Extraction temperature (120, 140, and 160°C) and time (20, 30, and 40 minutes) were selected as key variables. The optimal conditions, determined through modeling, were 142.87°C and 39.97 minutes. Under these conditions, the extraction yield reached 13.94%, total phenolic content (TPC) was 454.80 mg gallic acid equivalent (GAE) per 100 g, and free radical scavenging activity (DPPH) was 51.78%. Verification experiments confirmed these results. Additionally, the extracted compounds exhibited strong antimicrobial activity, with minimum inhibitory concentrations (MIC) of 10% and 5% against Penicillium citrinum and Aspergillus niger, respectively, compared to 1% for fluconazole. This study highlights the efficiency of subcritical water extraction in recovering bioactive compounds from agricultural byproducts, emphasizing its potential as a sustainable and effective method for producing valuable bioactive materials. | ||
| کلیدواژه‌ها [English] | ||
| phenolic compounds, orange peel waste, subcritical water, antimicrobial properties | ||
| مراجع | ||
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