اخبار و اعلانات

 آمار

تعداد نشریات282
تعداد نشریات سازمان80
تعداد شماره‌ها3,168
تعداد مقالات35,197
تعداد مشاهده مقاله50,932,191
تعداد دریافت فایل اصل مقاله90,937,582
Najafi-Olya, Zahra, Shakib, Pegah, Sepahdar, Asma, Hasanvand, Mohammad Hosein, Mousavi, Zahra, Sarvi, Pouya, Mirzania, Foroogh. (1405). Antimicrobial Effect of Pinus longifolia Roxb. ex.Lamb. and Pinus eldarica Medw. Fruits Hydroalcoholic Extract Against Candida albicans and Enterococcus faecalis. سامانه مدیریت نشریات علمی, 15(3), 347-352. doi: 10.22034/jmpb.2026.369987.2004
Zahra Najafi-Olya; Pegah Shakib; Asma Sepahdar; Mohammad Hosein Hasanvand; Zahra Mousavi; Pouya Sarvi; Foroogh Mirzania. "Antimicrobial Effect of Pinus longifolia Roxb. ex.Lamb. and Pinus eldarica Medw. Fruits Hydroalcoholic Extract Against Candida albicans and Enterococcus faecalis". سامانه مدیریت نشریات علمی, 15, 3, 1405, 347-352. doi: 10.22034/jmpb.2026.369987.2004
Najafi-Olya, Zahra, Shakib, Pegah, Sepahdar, Asma, Hasanvand, Mohammad Hosein, Mousavi, Zahra, Sarvi, Pouya, Mirzania, Foroogh. (1405). 'Antimicrobial Effect of Pinus longifolia Roxb. ex.Lamb. and Pinus eldarica Medw. Fruits Hydroalcoholic Extract Against Candida albicans and Enterococcus faecalis', سامانه مدیریت نشریات علمی, 15(3), pp. 347-352. doi: 10.22034/jmpb.2026.369987.2004
Najafi-Olya, Zahra, Shakib, Pegah, Sepahdar, Asma, Hasanvand, Mohammad Hosein, Mousavi, Zahra, Sarvi, Pouya, Mirzania, Foroogh. Antimicrobial Effect of Pinus longifolia Roxb. ex.Lamb. and Pinus eldarica Medw. Fruits Hydroalcoholic Extract Against Candida albicans and Enterococcus faecalis. سامانه مدیریت نشریات علمی, 1405; 15(3): 347-352. doi: 10.22034/jmpb.2026.369987.2004

Antimicrobial Effect of Pinus longifolia Roxb. ex.Lamb. and Pinus eldarica Medw. Fruits Hydroalcoholic Extract Against Candida albicans and Enterococcus faecalis

Journal of Medicinal plants and By-products
مقاله 6، دوره 15، شماره 3، مرداد و شهریور 2026، صفحه 347-352    اصل مقاله (2 M)
نوع مقاله: Research Paper
شناسه دیجیتال (DOI): 10.22034/jmpb.2026.369987.2004
نویسندگان
Zahra Najafi-Olya1؛ Pegah Shakib2؛ Asma Sepahdar2، 3؛ Mohammad Hosein Hasanvand4؛ Zahra Mousavi5؛ Pouya Sarvi6؛ Foroogh Mirzania* 2، 6
1Department of Medical Microbiology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
2Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran
3School of Dentistry, Lorestan University of Medical Sciences, Khorramabad, Iran
4Razi Herbal Medicines Research Center, student research committee, School of Dentistry, Lorestan University of Medical Sciences, Khorramabad, Iran
5Department of Restorative Dentistry, School of Dentistry, Lorestan University of Medical Sciences, Khorramabad, Iran
6Department of Pharmacognosy, Faculty of Pharmacy, Lorestan University of Medical Sciences, Khorramabad, Lorestan Province, Iran
چکیده
As a result of the growing resistance of pathogenic microorganisms to antibiotics, researchers are working to identify novel herbal medicines as an alternative to pharmaceutical medicines and antibiotics. The antimicrobial property of the hydroalcoholic extract of Pinus longifolia and P. eldarica fruits was examined in vitro with respect to Candida albicans and Enterococcus faecalis pathogens. P. longifolia and P. eldarica fruit hydroalcoholic extracts were made for this laboratory work, and the extracts' minimum inhibitory concentration (MIC), minimum bacterial killing concentration (MBC), and minimum fungal killing concentration (MFC) were measured. For E. faecalis and Candida albicans, the MIC of P. longifolia hydroalcoholic extract was 12.5 and 6.25 mg/ml, respectively. The MIC for the extract and chlorhexidine combination was 0.78 mg/ml. In the case of E. faecalis and C. albicans, the MIC of P. eldarica fruit hydroalcoholic extract was 12.5 and 6.25 mg/ml, respectively. The MIC of the extract + chlorhexidine against E. faecalis and C. albicans was 1.56 and 0.78 mg/ml, respectively. In comparison to the extract alone, the extract and chlorhexidine yielded superior results. Therefore, the combination of chlorhexidine and hydroalcoholic extracts of P. longifolia and P. eldarica could be a candidate for producing antimicrobial and strong intracanal rinsing compounds, which requires further investigation, including cytotoxicity assays for human cells and interaction with dentin or other detergents.
کلیدواژه‌ها
Pinus longifolia؛ Pinus eldarica؛ Hydroalcoholic extract؛ Antimicrobial effect؛ Enterococcus faecalis
سایر فایل های مرتبط با مقاله
مراجع
  1. Kishen A., Sum C-P., Mathew S., Lim C-T. Influence of irrigation regimens on the adherence of Enterococcus faecalis to root canal dentin. Journal of Endodontics. 2008; 34(7):850-4.
  2. Kayaoglu G., Erten H., Alaçam T., Ørstavik D. Short‐term antibacterial activity of root canal sealers towards Enterococcus faecalis. International Endodontic Journal. 2005; 38(7): 483-8.
  3. Kayaoglu G., Ørstavik D. Virulence factors of Enterococcus faecalis: relationship to endodontic disease. Critical Reviews in Oral Biology and Medicine. 2004; 15(5): 308-20.
  4. Sidhic J., George S., Narayanankutty A. Traditional medicinal plants in cancer therapy and chemoprevention: A review of preclinical and clinical studies. Current Nutrition and Food Science. 2024; 20(6):703-15.
  5. Jhajharia K., Parolia A., Shetty K.V., Mehta L. Biofilm in endodontics: A review. Journal of the International Society of Preventive and Community Dentistry. 2015; 5(1):1-12.
  6. Athanassiadis B., Abbott P., Walsh L. The use of calcium hydroxide, antibiotics and biocides as antimicrobial medicaments in endodontics. Australian Dental Journal. 2007; 52(1):S64-82.
  7. Leonardo M.R., Silva R.A.B., Assed S., Nelson-Filho P. Importance of bacterial endotoxin (LPS) in endodontics. Journal of Applied Oral Science. 2004; 12:93-8.
  8. Somaida A., Tariq I., Ambreen G., Abdelsalam A.M., Ayoub A.M., Wojcik M., et al. Potent cytotoxicity of four Cameroonian plant extracts on different cancer cell lines. Pharmaceuticals. 2020; 13(11):357.
  9. Tchinda C.F., Voukeng I.K., Beng V.P., Kuete V. Antibacterial activities of the methanol extracts of Albizia adianthifolia, Alchornea laxiflora, Laportea ovalifolia and three other Cameroonian plants against multidrug-resistant Gram-negative bacteria. Saudi Journal of Biological Sciences. 2017; 24(4):950-5.
  10. Zaïri A., Nouir S., M'hamdi N., Bennani M., Bergaoui I., Mtiraoui A., et al. Antioxidant, antimicrobial and phenolic content of infusion, decoction and methanolic extracts of thyme and Rosmarinus species. Current Pharmaceutical Biotechnology. 2018; 19(7):590-9.
  11. Moattar F.S., Mirpour M., Hemmati N. Effects of Pimpinella saxifraga L. extracts on environmental isolates of Enterococcus faecalis and HeLa cell line. Biotechnology Journal of Environmental Microorganisms. 2022; 1(2):100-6.
  12. Delfan B., Bahmani M., Hassanzadazar H., Saki K., Rafieian-Kopaei M. Identification of medicinal plants affecting headaches and migraines in Lorestan Province, west of Iran. Asian Pacific Journal of Tropical Medicine. 2014; 7(1):S376-9.
  13. Wolff R.L., Lavialle O., Pédrono F., Pasquier E., Destaillats F., Marpeau A.M., et al. Abietoid seed fatty acid composition: A review of the genera Abies, Cedrus, Hesperopeuce, Keteleeria, Pseudolarix, and Tsuga and preliminary inferences on the taxonomy of Pinaceae. Lipids. 2002; 37:17-26.
  14. Shuaib M., Ali M., Ahamad J., Naquvi K.J., Ahmad M. Pharmacognosy of Pinus roxburghii: A review. Journal of Pharmacognosy and Phytochemistry. 2013; 2(1):262-8.
  15. Khatun Z., Lawrence R.S., Jalees M., Lawrence K. Green synthesis and antibacterial activity of silver oxide nanoparticles prepared from Pinus longifolia leaves extract. International Journal of Advanced Research. 2015; 3(11):337-43.
  16. Kiaei M. Anatomical, physical, and mechanical properties of eldar pine (Pinus eldarica Medw.) grown in the Kelardasht region. Turkish Journal of Agriculture and Forestry. 2011; 35(1):31-42.
  17. Iravani S., Zolfaghari B. Green synthesis of silver nanoparticles using Pinus eldarica bark extract. BioMed Research International. 2013; 2013:639725.
  18. Iravani S., Zolfaghari B. Phytochemical analysis of Pinus eldarica bark. Research in Pharmaceutical Sciences. 2014; 9(4):243-50.
  19. Venkatesan T., Choi Y.W., Kim Y.K. Impact of different extraction solvents on phenolic content and antioxidant potential of Pinus densiflora bark extract. BioMed Research International. 2019; 2019:3520675.
  20. Morris S., Momen A. Study the antibacterial effects of alcoholic extract of Pelargonium sp. on the growth of three bacteria: Pseudomonas aeruginosa, Enterococcus faecalis and multidrug-resistant Escherichia coli. Journal of Ilam University of Medical Sciences. 2018; 26(4):23-33.
  21. Rakholiya K., Vaghela P., Rathod T., Chanda S. Comparative study of hydroalcoholic extracts of Momordica charantia L. against foodborne pathogens. Indian Journal of Pharmaceutical Sciences. 2014; 76(2):148-56.
  22. de Sousa E.S., Cortez A.C., de Souza Carvalho Melhem M., Frickmann H., de Souza J.V. Factors influencing susceptibility testing of antifungal drugs: A critical review of document M27-A4 from the Clinical and Laboratory Standards Institute (CLSI). Brazilian Journal of Microbiology. 2020; 51(4):1791-800.
  23. Abbey T.C., Deak E. What’s new from the CLSI subcommittee on antimicrobial susceptibility testing M100. Clinical Microbiology Newsletter. 2019; 41(23):203-9.
  24. Van Vuuren S. Antimicrobial natural product research: A review from a South African perspective for the years 2009–2016. Journal of Ethnopharmacology. 2017; 208:236-52.
  25. Norouzi Z., Madani M., Amjad L., Shakib P. Antifungal properties of Pinus eldarica and Pinus longifolia fruit extracts against Candida species isolated from vulvovaginal candidiasis patients. Current Drug Therapy. 2023; 18(4):333-41.
  26. Ghaffari T., Asnaashari S., Irannejad E., Delazar A., Farajnia S., Hong J.H., et al. Comparative evaluation of apoptosis induction using needles, bark, and pollen extracts and essential oils of Pinus eldarica in lung cancer cells. Applied Sciences. 2021; 11(13):5763.
  27. Sarvmeili N., Jafarian-Dehkordi A., Zolfaghari B. Cytotoxic effects of Pinus eldarica essential oil and extracts on HeLa and MCF-7 cell lines. Research in Pharmaceutical Sciences. 2016; 11(6):476-83.
  28. Khodadadnejad F., Akbari M., Abdolalian F., Daneshvar M., Ahmadi B., Zahraei Z. Comparison of antimicrobial activity of sodium hypochlorite (NaOCl) 2.5%, microemulsion of Myrtus 10%, and microemulsion of thyme 0.6% on Enterococcus faecalis after root canal filling. Journal of Arak University of Medical Sciences. 2021; 24(3):424-37.
  29. Vinothkumar T.S., Rubin M.I., Balaji L., Kandaswamy D. In vitro evaluation of five different herbal extracts as an antimicrobial endodontic irrigant using real-time quantitative polymerase chain reaction. Journal of Conservative Dentistry. 2013; 16(2):167-70.
  30. Radulescu V., Saviuc C., Chifiriuc C., Oprea E., Ilies D.C., Marutescu L., et al. Chemical composition and antimicrobial activity of essential oil from shoots of spruce (Picea abies L.). Revista de Chimie. 2011; 62(1):69-74.
  31. Iqbal Z., Zia-Ur-Rehman M., Khan S.J., Fatima A., Mehmud S. GC–MS studies of needle essential oils of Pinus roxburghii and their antimicrobial activity. Pakistan Journal of Biochemistry and Molecular Biology. 2011; 44:36-8.
آمار
تعداد مشاهده مقاله: 18
تعداد دریافت فایل اصل مقاله: 34


counter
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب