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Rahmani, Yasaman, Jamshidi, Shahram, Nayeri Fasaei, Bahar, Akbarein, Hesameddin, Joghataei, Seyed Mehdi, Mazloom-Jalali, Azin. (1404). The Impact of Scaling and Root Planing on Porphyromonas gingivalis Load and Periodontal Health in Dogs: A Longitudinal Study. سامانه مدیریت نشریات علمی, 80(6), 1401-1410. doi: 10.66224/ARI.80.6.3392
Yasaman Rahmani; Shahram Jamshidi; Bahar Nayeri Fasaei; Hesameddin Akbarein; Seyed Mehdi Joghataei; Azin Mazloom-Jalali. "The Impact of Scaling and Root Planing on Porphyromonas gingivalis Load and Periodontal Health in Dogs: A Longitudinal Study". سامانه مدیریت نشریات علمی, 80, 6, 1404, 1401-1410. doi: 10.66224/ARI.80.6.3392
Rahmani, Yasaman, Jamshidi, Shahram, Nayeri Fasaei, Bahar, Akbarein, Hesameddin, Joghataei, Seyed Mehdi, Mazloom-Jalali, Azin. (1404). 'The Impact of Scaling and Root Planing on Porphyromonas gingivalis Load and Periodontal Health in Dogs: A Longitudinal Study', سامانه مدیریت نشریات علمی, 80(6), pp. 1401-1410. doi: 10.66224/ARI.80.6.3392
Rahmani, Yasaman, Jamshidi, Shahram, Nayeri Fasaei, Bahar, Akbarein, Hesameddin, Joghataei, Seyed Mehdi, Mazloom-Jalali, Azin. The Impact of Scaling and Root Planing on Porphyromonas gingivalis Load and Periodontal Health in Dogs: A Longitudinal Study. سامانه مدیریت نشریات علمی, 1404; 80(6): 1401-1410. doi: 10.66224/ARI.80.6.3392

The Impact of Scaling and Root Planing on Porphyromonas gingivalis Load and Periodontal Health in Dogs: A Longitudinal Study

Archives of Razi Institute
مقاله 5، دوره 80، شماره 6، بهمن و اسفند 2025، صفحه 1401-1410    اصل مقاله (1.51 M)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.66224/ARI.80.6.3392
نویسندگان
Yasaman Rahmani1؛ Shahram Jamshidi* 1؛ Bahar Nayeri Fasaei2؛ Hesameddin Akbarein3؛ Seyed Mehdi Joghataei2؛ Azin Mazloom-Jalali4
1Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
2Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
3Department of Food Hygiene & Quality Control, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
4Department of Chemistry, School of Sciences, Amir Kabir University of Technology (Tehran Polytechnic), Tehran, Iran.
چکیده
Introduction: Periodontal disease is a widespread oral health issue in pets, particularly in dogs, linked to plaque accumulation, inflammation, and tissue destruction. Despite the common use of scaling and root planing (SRP) in veterinary dentistry, there is limited research on its effects on bacterial load and periodontal health indicators in pets, particularly in Iran. This study aims to evaluate the impact of SRP on Porphyromonas gingivalis load and periodontal health in dogs and emphasize the importance of post-treatment monitoring to prevent disease recurrence. 
Materials & Methods: Ten adult dogs with periodontal disease were selected for this split-mouth study. Four teeth from each dog were treated with SRP. Subgingival plaque samples were collected before SRP (baseline) and on days 10 and 30 post-treatment, with bacterial load assessed using real-time polymerase chain reaction (PCR) targeting P. gingivalis. Clinical parameters such as periodontal pocket depth (PPD), gingival index (GI), plaque index (PI), sulcus bleeding, and clinical attachment loss (CAL) were measured at baseline, day 10, and day 90 to monitor the effects of the intervention. 
Results: The data revealed a significant reduction in PI by day 10, though some plaque reaccumulation occurred by day 90. Bleeding on probing showed mixed results, with some dogs improving by day 90 while others either remained the same or worsened; changes in sulcus bleeding were not statistically significant. GI initially improved by day 10 but returned to baseline in many dogs by day 90, with no statistically significant changes. PPD showed some short-term improvements by day 10, but these were not sustained by day 90. CAL worsened progressively in most dogs by day 90, indicating ongoing periodontal deterioration without intervention, though changes in CAL were not statistically significant. Real-time PCR results showed a sharp increase in P. gingivalis load by day 10, peaking at a fold change of 9.45, followed by a slight reduction by day 30, indicating bacterial regrowth post-intervention.
Conclusion: This study highlights the importance of ongoing monitoring after SRP to sustain short-term improvements in plaque reduction and bacterial load. Future research should investigate the use of adjunctive therapies, including the application of nanotechnology, to improve long-term periodontal health in pets.
کلیدواژه‌ها
Gingival؛ Periodontal disease؛ Porphyromonas gingivalis؛ Real-time PCR؛ Scaling and root planning
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References

  1. Wallis C, Holcombe LJ. A review of the frequency and impact of periodontal disease in dogs. J Small Anim Pract. 2020; 61(9):529-40. [DOI:10.1111/jsap.13218] [PMID]
  2. Harvey C. The Relationship Between periodontal infection and systemic and distant organ disease in dogs. Vet Clin North Am Small Anim Pract. 2022; 52(1):121-37.[DOI:10.1016/j.cvsm.2021.09.004] [PMID]
  3. Lobprise HB, Dodd JRB. Wiggs’s veterinary dentistry: Principles and practice. Hoboken: John Wiley & Sons; 2019. [DOI:10.1002/9781118816219]
  4. Liu Y, Zhang C, Wu J, Yu H, Xie C. Evaluation of the relationship among dental fear, scaling and root planing and periodontal status using periodontitis stages: A retrospective study. J Dent Sci. 2022; 17(1):293-9. [DOI:10.1016/j.jds.2021.04.002] [PMID]
  5. Pullas KMH, Rocha WAS, Moncayo KNO, Medina GNN, Mestanza AMM, Esquivel JCZ. Efficacy of photodynamic therapy combined with scaling and root planning in the treatment of chronic periodontitis: A systematic literature review. Int J Med Sci Dent Health. 2024; 10(07):10-21. [DOI:10.55640/ijmsdh-10-07-02]
  6. Niemiec B. Veterinary periodontology. Hoboken: John Wiley & Sons; 2013. [DOI:10.1002/9781118705018]
  7. Oz HS, Puleo DA. Animal models for periodontal disease. J Biomed Biotechnol. 2011; 2011:754857.[DOI:10.1155/2011/754857] [PMID]
  8. Xu W, Zhou W, Wang H, Liang S. Chapter two - roles of Porphyromonas gingivalis and its virulence factors in periodontitis. In: Donev R, editor. Advances in Protein Chemistry and Structural Biology. Cambridge: Academic Press; 2020. [DOI:10.1016/bs.apcsb.2019.12.001]
  9. Zhang Z, Liu D, Liu S, Zhang S, Pan Y. The role of porphyromonas gingivalis outer membrane vesicles in periodontal disease and related systemic diseases. Front Cell Infect Microbiol. 2021; 10:585917. [DOI:10.3389/fcimb.2020.585917] [PMID]
  10. Gasmi Benahmed A, Kumar Mujawdiya P, Noor S, Gasmi A. Porphyromonas gingivalis in the development of periodontitis: Impact on dysbiosis and inflammation. Arch Razi Inst. 2022; 77(5):1539-51. [DOI:10.22092/ARI.2021.356596.1875] [PMID]
  11. Joghataei S, Nikaein D, Arshadi Nezhad G, Khosravi A, Ashrafi Tamai I. Impact of Nano-Pomegranate Seed Oil on the Expression of TLR2 and TLR4 Genes in A549 Cells Sensitized with Alternaria alternata Cellular Extract. J Med Bacteriol. 2024. [DOI:10.18502/jmb.v12i4.17004]
  12. Niaraki NJ, Jamshidi S, Fasaei BN, Joghataei SM. Antibacterial effects of chitosan-based hydrogels containing Trachyspermum ammi essential oil on pathogens isolated from dogs with otitis externa. BMC Vet Res. 2024; 20(1):130. [DOI:10.1186/s12917-024-03971-7] [PMID]
  13. Assaf M, Yilmaz S, Kuru B, Ipci SD, Noyun U, Kadir T. Effect of the diode laser on Bacteremia associated with dental ultrasonic scaling: A clinical and microbiological study. Photomed Laser Surg. 2007; 25(4):250-6. [DOI:10.1089/pho.2006.2067] [PMID]
  14. Gorrel C. Veterinary dentistry for the general practitioner.Amsterdam: Elsevier; 2013. [Link]
  15. Bellows J. Small animal dental equipment, materials, and techniques. Hoboken: John Wiley & Sons; 2019. [DOI:10.1002/9781118986646]
  16. Salim RU, Soeroso Y, Masulili SLC, Bachtiar BM, Sunarto H. Scaling and root planning effects on alveolar bone density and amount of Porphyromonas gingivalis and Treponema denticola. J Phys Conf Ser. 2018; 1073(6):062010. [DOI:10.1088/1742-6596/1073/6/062010]
  17. No Author. WikiVet [Internet]. 2026 [Updated 25 January 2026]. Available from: [Link]
  18. Niemiec B, Gawor J, Nemec A, Clarke D, McLeod K, Tutt C, et al. World small animal veterinary association global dental guidelines. J Small Anim Pract. 2020; 61(7):E36-161. [DOI:10.1111/jsap.13132]
  19. Marshall MD, Wallis CV, Milella L, Colyer A, Tweedie AD, Harris S. A longitudinal assessment of periodontal disease in 52 Miniature Schnauzers. BMC Vet Res. 2014; 10:166. [DOI:10.1186/1746-6148-10-166] [PMID]
  20. Dominy SS, Lynch C, Ermini F, Benedyk M, Marczyk A, Konradi A, et al. Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors. Sci Adv. 2019; 5(1):eaau3333. [DOI:10.1126/sciadv.aau3333] [PMID]
  21. Li L, Hayashi-Okada Y, Falkner KL, Cervi S, Andrusz S, Shimizu Y, et al. Randomized trial to test a chemo-mechanical antiplaque regimen as adjunct to periodontal therapy. JDR Clin Trans Res. 2024; 9(2):160-9. [DOI:10.1177/23800844231167065] [PMID]
  22. Liu G, Luan Q, Chen F, Chen Z, Zhang Q, Yu X. Shift in the subgingival microbiome following scaling and root planing in generalized aggressive periodontitis. J Clin Periodontol. 2018; 45(4):440-52. [DOI:10.1111/jcpe.12862] [PMID]
  23. Maruyama N, Mori A, Shono S, Oda H, Sako T. Evaluation of changes in periodontal bacteria in healthy dogs over 6 months using quantitative real-time PCR. Pol J Vet Sci. 2018; 21(1):127-32. [DOI:10.24425/119030] [PMID]
  24. Polkowska I, Tymczyna-Borowicz B, Gołyńska M, Nowicka B. Molecular microbiological characteristics of gingival pockets in the periodontal diseases of dogs. J Vet Res. 2023; 67(1):115-22. [DOI:10.2478/jvetres-2023-0005] [PMID]
  25. Aleksijević LH, Aleksijević M, Škrlec I, Šram M, Šram M, Talapko J. Porphyromonas gingivalis virulence factors and clinical significance in periodontal disease and coronary artery diseases. Pathogens. 2022; 11(10):1173. [DOI:10.3390/pathogens11101173] [PMID]
  26. Oteo A, Herrera D, Figuero E, O’Connor A, González I, Sanz M. Azithromycin as an adjunct to scaling and root planing in the treatment of Porphyromonas gingivalis-associated periodontitis: A pilot study. J Clin Periodontol. 2010; 37(11):1005-15. [DOI:10.1111/j.1600-051X.2010.01607.x] [PMID]
  27. Shirmohammadi A, Maleki Dizaj S, Sharifi S, Fattahi S, Negahdari R, Ghavimi MA, et al. Promising antimicrobial action of sustained released curcumin-loaded silica nanoparticles against clinically isolated porphyromonas gingivalis. Diseases. 2023; 11(1):48. [DOI:10.3390/diseases11010048] [PMID]
  28. Namdar N, Nayeri Fasaei B, Shariati P, Joghataei SM, Arpanaei A. Mesoporous silica nanoparticles co-loaded with lysozyme and vancomycin for synergistic antimicrobial action. Sci Rep. 2024; 14(1):29242. [DOI:10.1038/s41598-024-78922-1] [PMID]
  29. Eick S, Renatus A, Heinicke M, Pfister W, Stratul SI, Jentsch H. Hyaluronic acid as an adjunct after scaling and root planing: A prospective randomized clinical trial. J Periodontol. 2013; 84(7):941-9. [DOI:10.1902/jop.2012.120269] [PMID]
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