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Sewoyo, Palagan Senopati, Nainggolan, Willy Moris, Kardena, I Made, Winaya, Ida Bagus Oka, Gunawan, I Wayan Nico Fajar, Dewi, Ida Ayu Dian Kusuma. (1404). A Case of Urothelial Carcinoma in Situ of the Bladder in Local Dog in Bali, Indonesia. سامانه مدیریت نشریات علمی, 80(5), 1345-1352. doi: 10.32598/ARI.80.5.3808
Palagan Senopati Sewoyo; Willy Moris Nainggolan; I Made Kardena; Ida Bagus Oka Winaya; I Wayan Nico Fajar Gunawan; Ida Ayu Dian Kusuma Dewi. "A Case of Urothelial Carcinoma in Situ of the Bladder in Local Dog in Bali, Indonesia". سامانه مدیریت نشریات علمی, 80, 5, 1404, 1345-1352. doi: 10.32598/ARI.80.5.3808
Sewoyo, Palagan Senopati, Nainggolan, Willy Moris, Kardena, I Made, Winaya, Ida Bagus Oka, Gunawan, I Wayan Nico Fajar, Dewi, Ida Ayu Dian Kusuma. (1404). 'A Case of Urothelial Carcinoma in Situ of the Bladder in Local Dog in Bali, Indonesia', سامانه مدیریت نشریات علمی, 80(5), pp. 1345-1352. doi: 10.32598/ARI.80.5.3808
Sewoyo, Palagan Senopati, Nainggolan, Willy Moris, Kardena, I Made, Winaya, Ida Bagus Oka, Gunawan, I Wayan Nico Fajar, Dewi, Ida Ayu Dian Kusuma. A Case of Urothelial Carcinoma in Situ of the Bladder in Local Dog in Bali, Indonesia. سامانه مدیریت نشریات علمی, 1404; 80(5): 1345-1352. doi: 10.32598/ARI.80.5.3808

A Case of Urothelial Carcinoma in Situ of the Bladder in Local Dog in Bali, Indonesia

Archives of Razi Institute
مقاله 27، دوره 80، شماره 5، آذر و دی 2025، صفحه 1345-1352    اصل مقاله (2.65 M)
نوع مقاله: Case Study
شناسه دیجیتال (DOI): 10.32598/ARI.80.5.3808
نویسندگان
Palagan Senopati Sewoyo* 1؛ Willy Moris Nainggolan2؛ I Made Kardena1؛ Ida Bagus Oka Winaya1؛ I Wayan Nico Fajar Gunawan3؛ Ida Ayu Dian Kusuma Dewi3
1Laboratory of Veterinary Pathology, Faculty of Veterinary Medicine, Udayana University, Bali, Indonesia.
2BVC Animal Hospital, Bali, Indonesia.
3Laboratory of Veterinary Clinical Diagnosis, Clinical Pathology, and Radiology, Faculty of Veterinary Medicine, Udayana University, Bali, Indonesia.
چکیده
Urothelial carcinoma is a malignant neoplasm of the urinary tract arising from the transitional epithelium. Its clinical manifestations often overlap with non-neoplastic conditions, such as urinary tract infections, thereby presenting a diagnostic challenge for clinicians. Differentiating from others condition is important, as the treatment and prognoses vary significantly. This case report presented a 4-year-old female local dog, weighing 11.55 kg in BVC Animal Hospital with a primary complaint of hematuria. Clinical, hematological, and serum biochemical evaluations revealed no significant abnormalities. Ultrasonographic (USG) examination identified a hypoechoic mass measuring 0.31×0.85 cm located within the lumen and thickening of urinary bladder wall. Cytological assessment was performed via urine catheterization. The cytological specimen demonstrated a population of cells with anisocytosis, anisokaryosis, and a high nucleus-to-cytoplasm ratio, raising suspicion of a malignant tumor. Consequently, biopsy was performed via cystotomy to establish a definitive diagnosis. Prior to release the histopathological results, post-cystotomy the dog was treated with cefadroxil as antibiotics at 20 mg/kg BW b.i.d for 14 days, carprofen as anti-inflammatory at 2 mg/kg BW s.i.d. for 5 days, and tramadol as analgesics at 2 mg/kg BW b.i.d. for 5 days. Histopathological examination showed a non-encapsulated tumor with well-defined demarcation in the mucosa. The tumor consists of a dense population of epithelial tumor cells without evidence of invasion, confirmed the diagnosis of non-invasive, non-papillary urothelial carcinoma (in situ). The patient was managed palliatively with the administration of piroxicam at 0.3 mg/kg BW s.i.d as monotherapy. Until day 190, the dog showing a stable disease. To the best of the authors’ knowledge, this is the first documented case of canine urothelial carcinoma in Indonesia
کلیدواژه‌ها
Bladder cancer؛ Dog؛ Palliative therapy؛ Transitional cell carcinoma
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مراجع

References

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