| تعداد نشریات | 282 |
| تعداد نشریات سازمان | 80 |
| تعداد شماره‌ها | 3,272 |
| تعداد مقالات | 36,149 |
| تعداد مشاهده مقاله | 55,713,670 |
| تعداد دریافت فایل اصل مقاله | 94,492,305 |
Impacts of HVT Vaccination Against Marek’s Disease in Broiler Chickens in Algeria | ||
| Archives of Razi Institute | ||
| مقاله 18، دوره 81، شماره 1، فروردین و اردیبهشت 2026، صفحه 157-164 اصل مقاله (542.29 K) | ||
| نوع مقاله: Original Articles | ||
| شناسه دیجیتال (DOI): 10.66224/ARI.81.1.3672 | ||
| نویسندگان | ||
| Samia Ameziane1؛ Salim Zaidi1؛ Omar Salhi2؛ Amina Amraoui1؛ Aya Bensalem1؛ Nadjet Amina Khelifi Touhami* 2؛ Nassim Ouchene2؛ Sana Hireche1؛ Amir Agabou1 | ||
| 1PADESCA Laboratory, Institute of Veterinary Sciences, University of Mentouri Brothers, Constantine, Algeria. | ||
| 2Institute of Veterinary Sciences, University Saad Dahlab Blida 1, Blida, Algeria. | ||
| چکیده | ||
| Introduction: Marek’s disease (MD), a lymphoproliferative and immunosuppressive viral disease of poultry, poses serious challenges to broiler production worldwide. Vaccination with turkey herpesvirus (HVT) is a common preventive strategy. This study aimed to evaluate the zootechnical and economic impacts of HVT vaccination in broiler chickens reared under field conditions in northeastern Algeria. Materials & Methods: The trial was conducted in the Mila Region over six weeks and involved two cohorts of 11,000 broiler chickens each: A vaccinated group (VG) receiving HVT vaccination on day 1 in addition to standard vaccinations, and a non-vaccinated group (NVG). Both groups were sourced from the same breeder stock and raised under identical management and environmental conditions. Key parameters measured included average body weight (BW), feed conversion ratio (FCR), and weekly mortality. Economic viability was assessed through a cost-benefit analysis (CBA), considering vaccination costs (218.66 EUR) and estimated production gains. Results: From week four onward, VG birds showed significantly higher BW than NVG, reaching 3070 g vs 3000 g at week six (P<0.001). FCR remained comparable between groups, with VG showing slightly improved efficiency from week three, though not statistically significant (P=0.93). Mortality rates (MR) were significantly lower in VG from week three onward, with pooled analysis confirming a protective effect of vaccination (P<0.01). The improved growth performance and reduced mortality observed in the VG suggest a clear health benefit of HVT vaccination in broilers raised under field conditions. Despite no significant difference in feed conversion efficiency, the biological impact of the vaccine was evident from mid-trial onwards, highlighting the protective effect of HVT against MD-related losses. HVT vaccination in broilers enhances growth performance and significantly reduces mortality without compromising feed efficiency. Economically, it proves to be a highly viable strategy, resulting in a net benefit of 5489.74 EUR per flock and a cost-benefit ratio of 26-to-1. Conclusion: These findings support the integration of HVT vaccination into comprehensive health management programs in intensive poultry systems. | ||
| کلیدواژه‌ها | ||
| Broiler chicken؛ Economic impact؛ HVT vaccine؛ Marek’s disease (MD) | ||
|
سایر فایل های مرتبط با مقاله
|
||
| مراجع | ||
|
Reddy YV, Kumar AA, Amaravathi P. Diagnosis of Marek’s disease through histological, immunohistochemical and molecular applications: A comparative study. Indian J Vet Pathol. 2022; 46(3):201-7. [DOI:10.5958/0973-970X.2022.00033.5]
Faiz NM, Cortes AL, Guy JS, Reddy SM, Gimeno IM. Differential attenuation of Marek's disease virus-induced tumours and late-Marek's disease virus-induced immunosuppression. J Gen Virol. 2018; 99(7):927-36. [DOI:10.1099/jgv.0.001076] [PMID]
Venugopal K, Payne LN. Molecular pathogenesis of Marek’s disease - recent developments. Avian Pathol. 1995; 24(4):597-609. [DOI:10.1080/03079459508419100] [PMID]
Calnek BW. Pathogenesis of Marek’s disease virus infection. Curr Top Microbiol Immunol. 2001; 255:25-55. [DOI:10.1007/978-3-642-56863-3_2] [PMID]
Calnek BW, Harris RW, Buscaglia C, Schat KA, Lucio B. Relationship between the immunosuppressive potential and the pathotype of Marek’s disease virus isolates. Avian Dis. 1998; 42(1):124-32. [DOI:10.2307/1592584] [PMID]
Ozan E, Muftuoglu B, Sahindokuyucu I, Kurucay H, Inal S, Kuruca N, et al. Marek’s disease virus in vaccinated poultry flocks in Turkey: Its first isolation with molecular characterization. Arch Virol. 2021; 166(2):559-69. [DOI:10.1007/s00705-020-04943-6] [PMID]
Gimeno IM, Cortes AL, Faiz N, Villalobos T, Badillo H, Barbosa T. Efficacy of various HVT vaccines (conventional and recombinant) against Marek’s disease in broiler chickens: Effect of dose and age of vaccination. Avian Dis. 2016; 60(3):662-8. [DOI:10.1637/11415-040116-Reg.1] [PMID]
Toma B, Dufour B, Bénet JJ, Sanaa M, Shaw A, Moutou F. Analyse économique comme aide à la décision en santé animale. In: Épidémiologie appliquée: la lutte collective contre les maladies animales transmissibles majeures. 3rd ed. France: AEEMA; 2010. [Link]
Islam AF, Wong CW, Walkden-Brown SW, Colditz IG, Arzey KE, Groves PJ. Immunosuppressive effects of Marek’s disease virus (MDV) and herpesvirus of turkeys (HVT) in broiler chickens and the protective effect of HVT vaccination against MDV challenge. Avian Pathol. 2002; 31(5):449-61. [DOI:10.1080/0307945021000005824] [PMID]
Faiz NM, Cortes AL, Guy JS, Fletcher OJ, Cimino T, Gimeno IM. Evaluation of factors influencing the development of late Marek’s disease virus-induced immunosuppression: Virus pathotype and host sex. Avian Pathol. 2017; 46(4):376-85. [DOI:10.1080/03079457.2017.1290214] [PMID]
Abbassi H, Dambrine G, Cherel Y, Coudert F, Naciri M. Interaction of Marek’s disease virus and Cryptosporidium baileyi in experimentally infected chickens. Avian Dis. 2000; 44(4):776-89. [DOI:10.2307/1593049] [PMID]
López-Osorio S, Piedrahita D, Espinal-Restrepo MA, Ramírez-Nieto GC, Nair V, Williams SM, et al. Molecular characterization of Marek's disease virus in a poultry layer farm from Colombia. Poult Sci. 2017; 96(6):1598-608.[DOI:10.3382/ps/pew464] [PMID]
Zeghdoudi M, Merdaci L, Madi S, Sadeddine R, Tahri M, Aoun L. Updating of epidemiological and pathological features of Marek’s disease in laying hens and broilers. Vet Med (Praha). 2023; 68(11):443-8. [DOI:10.17221/75/2023-VETMED][PMID]
Culling CFA. Handbook of histopathological and histochemical techniques. London: Butterworth-Heinemann; 1974. [Link]
Pan X, Liu Q, Niu S, Huang D, Yan D, Teng Q, et al. Efficacy of a recombinant turkey herpesvirus (H9) vaccine against H9N2 avian influenza virus in chickens with maternal-derived antibodies. Front Microbiol. 2023; 13:1107975. [DOI:10.3389/fmicb.2022.1107975][PMID]
Litao L, Feng C, Hongyu Z, Wenbin C, Fanlei M, Dandan Z, et al. Field production efficiency investigation of broilers immunized with a turkey herpesvirus vector vaccine expressing hemagglutinin from H9N2 subtype avian influenza virus. Vaccine. 2024; 42(26):126436. [DOI:10.1016/j.vaccine.2024.126436] [PMID]
Lemiere S. The cost benefits of vaccination in poultry production. Int Poult Prod. 2013; 21:19-21. [Link]
Wegner M, Kokoszyński D, Włodarczyk K. Effect of different vaccination programs on production parameters, carcass, leg bones, and digestive system characteristics of broilers. Poult Sci. 2023; 102(6):102668. [DOI:10.1016/j.psj.2023.102668][PMID]
Witter RL, Offenbecker L. Duration of vaccinal immunity against Marek’s disease. Avian Dis. 1978; 22(3):396-408. [DOI:10.2307/1589295]
Norcross MA, Rankin AD. Experience with Marek's disease vaccine. Poult Sci. 1973; 52(3):836-41. [DOI:10.3382/ps.0520836] [PMID]
Dejyong T, Chanachai K, Prarakamawongsa T, Kongkaew W, Thiptara A, Songserm T, et al. Economic and value chain analysis to support an investigation and risk mitigation efforts on Marek’s disease in layers in the southern part of Thailand. Vet World. 2023; 16(1):35-45. [DOI:10.14202/vetworld.2023.35-45][PMID]
Lounas A, Besbaci M, Akkou M, Tali O. Occurrence of Marek’s disease in vaccinated Algerian broiler breeder flocks: A histopathological survey. Vet World. 2021; 14(11):3021-7. [DOI:10.14202/vetworld.2021.3021-3027] [PMID] | ||
|
آمار تعداد مشاهده مقاله: 711 تعداد دریافت فایل اصل مقاله: 516 |
||
