| تعداد نشریات | 282 |
| تعداد نشریات سازمان | 80 |
| تعداد شماره‌ها | 3,251 |
| تعداد مقالات | 35,918 |
| تعداد مشاهده مقاله | 54,605,349 |
| تعداد دریافت فایل اصل مقاله | 93,707,365 |
بررسی کارایی یک مکمل آهسته رهش ید در پیشگیری از عوارض کمبود ید در میش های داشتی | ||
| علوم دامی | ||
| دوره 38، شماره 146، خرداد 1404، صفحه 89-102 اصل مقاله (2.39 M) | ||
| نوع مقاله: مقاله پژوهشی | ||
| شناسه دیجیتال (DOI): 10.22092/asj.2024.365249.2374 | ||
| نویسنده | ||
| علیرضا طالبیان مسعودی* | ||
| استادیار، بخش علوم دامی، مرکز تحقیقات و آموزش کشاورزی و منابع طبیعی استان مرکزی (نویسنده مسئول). | ||
| چکیده | ||
| این تحقیق با هدف ساخت و بررسی کارایی روغن بادام زمینی ید دار شده در پیشگیری از عوارض کمبود ید در گوسفند انجام شد. ابتدا اتیل استر ید دار شده اسیدهای چرب روغن بادام زمینی ساخته شد سپس یک گله گوسفند داشتی با سابقه کمبود ید انتخاب گردید و در این گله، تعداد 30 رأس میش جوان از توده نژاد فراهانی با وزن بدن مشابه (4 ± 42 کیلوگرم) به‌صورت تصادفی به سه گروه شامل شاهد و دو گروه آزمایشی (سه تیمار و 10 تکرار) تقسیم شدند. گروه آزمایشی اول، مقدار 390 میلی گرم ید به شکل اتیل استر اسیدهای چرب روغن بادام زمینی و گروه آزمایشی دوم، همین مقدار ید را از مکمل مشابه خارجی با نام تجارتی دپودین (®Depodine ) در اواخر آبستنی در انتهای فصل زمستان دریافت کردند. مدت زمان اجرای آزمایش سه ماه بود که طی آن غلظت ید معدنی سرم و هورمون‌های تیروئیدی شامل T3، T4 در شروع آزمایش و ماهیانه در گروه‌های آزمایشی اندازه‌گیری و مقایسه شد. هر دو مکمل ید باعث افزایش معنی‌دار غلظت ید معدنی سرم خون در گروه‌های آزمایشی نسبت به گروه شاهد در هر سه ماه نمونه‌برداری شدند ((01/0< P)و هر دو مکمل باعث افزایش تولید و غلظت هورمون‌های T4 و T3 در کل دوره آزمایش نسبت به مقدار پایه و گروه شاهد گردیدند ((01/0< P). نتایج نشان داد که ساخت این هورمون‌ها تحت تأثیر کمبود ید قرار داشته‌اند و مکمل تهیه شده در پیشگیری از عوارض کمبود ید در دام موثر و دارای اثر مشابهی با نمونه خارجی می‌باشد. | ||
| کلیدواژه‌ها | ||
| تیروکسین؛ تری‌یدوتیرونین؛ گوسفند؛ روغن یددار؛ بادام زمینی | ||
| عنوان مقاله [English] | ||
| The efficacy of a slow release iodine supplement in preventing iodine deficiency disorders in ewes | ||
| نویسندگان [English] | ||
| Alireza Talebian Masoudi | ||
| Department of Animal science, Markazi Agricultural and Natural Resource Research and Education Center, Arak, Iran, | ||
| چکیده [English] | ||
| This research was conducted to produce and study the effect of iodinated peanut oil on preventing iodine deficiency disorders (IDD) in sheep. Iodinated fatty acid ethyl esters prepared from peanut oil (IFAEEpo). Thirty Farahani ewes (average body weight ± standard deviation = 42±4 kg) with a history of iodine deficiency were divided into three groups, including one control and two treatment groups. The treatment groups received 390 mg iodine by intramuscular injection of IFAEEpo (n = 10) or Depodine® (n = 10), respectively in late gestation at the end of winter. The duration of the study was three months, and serum iodine and thyrotropin-stimulating hormone (TSH), T3 and T4 concentrations were determined at baseline and every 30-day intervals over a period of three months. The serum iodine concentration of the test animals was 15.14 μg/litre at the beginning of the trial and thus in the deficiency range. Both iodine supplements caused a significant increase in serum iodine concentration in the experimental groups compared to the control group in all three months of sampling (P < 0.01), and both supplements increased the production and concentration of T4 and T3 hormones in the entire experimental period. The increase in serum mineral iodine concentration and thyroid hormones after iodine supplementation showed that the production of these hormones was affected by iodine deficiency and that the supplement produced was effective in preventing the iodine deficiency disorders in livestock and had a similar effect to the foreign ones. | ||
| کلیدواژه‌ها [English] | ||
| Thyroxine, Thriiodithyronine, Sheep, Iodized oil, Peanut | ||
| مراجع | ||
|
AOAC International. AOAC Official Method 28.023, Iodine Absorption Number Wijs Method; Official Methods of Analysis of AOAC International: Arlington, TX, USA,1984. Azizi, F. (2007). Iodized oil: its role in the management of iodine deficiency disorders. International Journal of Endocrinology and Metabolism, 2, 91–98. Azizi, F., Kimiagar, M., Ghazi, A.A., and Nafarabadi, M. (1997). The effects of iodized oil injection in eu-and hypothyroid iodine deficient girls. Journal of Endocrinological Investigation, 20,18–23. Bhardwaj, R.K. (2018). Iodine deficiency in goats. Goat Science. IntechOpen, Rijeka,London (UK). https://doi.org/10.5772/intechopen.72728. Çakalo˘glu, B., ¨Ozyurt, V.H., and ¨Otles¸, S. (2018). Cold press in oil extraction. a review. Ukrainian Food Journal, 7 (4), 640–654. https://doi.org/10.24263/2304-974X-2018-7-4-9. Chung, H.R. (2014). Iodine and thyroid function. Annals of Pediatric Endocrinology and Metabolism, 19 (1),8–12. https://doi.org/10.6065/apem.2014.19.1.8. Colodel, M.M., Martins, E., Martins, V.M.V., and Marques Júnior, A.P. (2010). Serum concentration of thyroid hormones in crioula lanada serrana ewes in gestation and lactation. Arch. Zootec, 59 (228), 509–517. Delshad, H., and Azizi, F. (2017). Review of iodine nutrition in Iranian population in the past quarter of century. International Journal of Endocrinology and Metabolism, 15 (4). https://doi.org/10.5812/ijem.57758. Davoodi, F., Zakian, A., Rocky, A., and Raisi, A. (2022). Incidence of iodine deficiency and congenital goitre in goats and kids of Darreh Garm region, Khorramabad, Iran. Veterinary Medicine and Science, 8 (1), 336–342. https://doi.org/10.1002/vms3.661. Delange, F., Dunn, J.T., and Glinoer, D. (2013). Iodine deficiency in Europe: a continuing concern (Eds.). Springer Science & Business Media. (Vol. 241). Dunn, J.T., and Haar, F.V.D. (1990). A practical guide to the correction of iodine deficiency.[Sl]: International Council for Control of Iodine Deficiency Disorders. https://apps.who.int/iris/handle/10665/39840. EFSA. (2013). Scientific opinion on the safety and efficacy of Iodine compounds (E2) as feed additives for all species: calcium iodate anhydrous (coated granulated preparation) based on a dossier submitted by Doxal Italia S.p A. EFSA J. 11 (3), 3178. doi: 10.2903/j.efsa.2013.3178 Ferri, N., Ulisse, S., Aghini-Lombardi, F., Graziano, F.M., Di Mattia, T., Russo, F.P.,Arizzi, M., Baldini, E., Trimboli, P., Armiento, D., and Fumarola, A. (2003). Iodine supplementation restores fertility of sheep exposed to iodine deficiency. Journal of Endocrinological Investigation, 26 (11), 1081–1087. https://doi.org/10.1007/BF03345254. Flis, Z., and Molik, E. (2021). Changes in the concentrations of thyroid hormones in dairy sheep. Rocz. Nauk. Pol. Tow. Zootech, 17 (1), 7–12. https://doi.org/10.5604/01.3001.0014.7041. Gunawan, R., and Nandiyanto, A.B.D. (2021). How to read and interpret 1H NMR and 13C NMR spectrums, 269. Indonesian Journal of Science and Technology, 6 (2), 267–298. https://doi.org/10.17509/ijost.v6i2.34189. Herzig, I., Pisarikova, B., Diblikova, I., and Suchy, P. (2001). Iodine concentrations in porcine blood, urine, and tissues after a single dose of iodised oil. veterinary medicine, 46 (6), 153–159.https://doi.org/10.17221/7875-VETMED. Ingenbleek, Y., Jung, L., Ferard, G., Bordet, F., Dechoux, L., and Goncalves, A.M. (1997). Iodised rapeseed oil for eradication of severe endemic goitre. Lancet, 350,1542–1545. Knowles, S.O., and Grace, N.D. (2007). A practical approach to managing the risks of iodine deficiency in flocks using thyroid-weight: birthweight ratios of lambs. New Zealand Veterinary Journal, 55(6), 314–318. Knowles, S.O., and Grace, N.D. (2015). Serum total iodine concentrations in pasture-fed pregnant ewes and newborn lambs challenged by iodine supplementation and goitrogenic kale. Journal of Animal Science, 93 (1), 425–432. https://doi.org/10.2527/jas2014-7854. Leung, A.M., and Braverman, L.E. (2012). Iodine-induced thyroid dysfunction. Current Opinion in Endocrinology, Diabetes and Obesity, 19 (5), 414–419. https://doi.org/10.1097/MED.0b013e3283565bb2. Mirmiran, P., Kimiagar, M., and Azizi, F. (2002). Three-year survey of effects of iodized oil injection in schoolchildren with iodine deficiency disorders. Experimental and Clinical Endocrinology & Diabetes, 110 (08), 393–397. https://doi.org/10.1055/s-2002-36425. Noori, O. S., Rad, M. M., and Ansari, M. H. (2017). Evaluation of grain yield, land equivalent ratio and fatty acids combination of peanut oil in intercropping with corn as affected by different levels of nitrogen. Journal of Crops Improvement, 18(4) 805-820. NRC. (National Academy of Science) (1985). Nutrient requirements for sheep. 6th rev. edn (Washington DC, National Academy Press). Parker, W.J., and Mc Cutcheon, S.N. (1989). Effects of iodine supplementation on the productivity of Romney ewes in the Wairarapa region of New Zealand. New Zealand Journal of Agricultural Research, 32 (2), 207–212. https://doi.org/10.1080/00288233.1989.10423455. Pineda, M.H., and Dooley, M.P. (2003). McDonald’s Veterinary Endocrinology and Reproduction. Iowa State Press, Ames, IA, USA. ISBN 9780813811062. Sandell, E.B., and Kolthoff, I.M. (1937). Micro determination of iodine by a catalytic method. Microchem. Acta. 1, 9–25. Sankar, R., Pandav, C.S., Ahmed, F.U., Rao, Pralhad, Dwivedi, M.P., Desai, V., Karmarka, M.G., and Nath, L.M. (1995). Review of experiences with iodized oil in national programs for control of iodine deficiency disorders. Indian Journal of Pediatrics, 62 (4),381–393. Sargison, N.D., West, D.M., and Clark, R.G. (1997). An investigation of the possible effects of subclinical iodine deficiency on ewe fertility and perinatal lamb mortality. New Zealand Veterinary Journal, 45 (5), 208–211. Skripkin, V., Kvochko, A., Derezina, T., Kuzminova, A., Cymbal, I., Belugin, N., and Pisarenko, N. (2019). Dynamics of thyroid hormones in Stavropol breed sheep in postnatal ontogenesis. IOP Conf. Ser. Environmental Earth Sciences, 403, 1. https://doi.org/10.1088/1755-1315/403/1/012064. Sorrenti, S., Baldini, E., Pironi, D., Lauro, A., D’Orazi, V., Tartaglia, F., Tripodi, D., Lori, E., Gagliardi, F., Pratic`o, M., and Illuminati, G. (2021). Iodine: its role in thyroid hormone biosynthesis and beyond. Nutrients, 13 (12), 4469. Talebian Masoudi, A.R., Azizi, F., and Zahedipour, H. (2010). Selenium and iodine status of sheep in the Markazi province. Iranian Journal of Veterinary Research, 11 (1), 78–83. Talebian Masoudi, and A.R., Mirshamsollahi, A. (2022). The effect of iodine supplementation on growth performance, reproductive parameters and thyroid hormones of sheep in some areas of Markazi province, Iran. Journal of Ruminant Research, 10 (3), 71-86. Wolff, J. (2001). Physiology and pharmacology of iodized oil in goiter prophylaxis. Medicine, 80 (1), 20–36. World Health Organization (2007). Assessment of iodine deficiency disorders and monitoring their elimination: a guide for programme managers, 3rd ed, WHO, Geneva, Switzerland. | ||
|
آمار تعداد مشاهده مقاله: 329 تعداد دریافت فایل اصل مقاله: 225 |
||