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Raziani, Yosra, Sepahvand, Azadeh, Masoori, Leila, Baharvand, Parastoo, Mahmoudvand, Hossein. (1404). Seroprevalence and Associated Risk Factors of Toxocariasis in Children With Hypereosinophilia in Iran. سامانه مدیریت نشریات علمی, 80(6), 1429-1436. doi: 10.66224/ARI.80.6.3403
Yosra Raziani; Azadeh Sepahvand; Leila Masoori; Parastoo Baharvand; Hossein Mahmoudvand. "Seroprevalence and Associated Risk Factors of Toxocariasis in Children With Hypereosinophilia in Iran". سامانه مدیریت نشریات علمی, 80, 6, 1404, 1429-1436. doi: 10.66224/ARI.80.6.3403
Raziani, Yosra, Sepahvand, Azadeh, Masoori, Leila, Baharvand, Parastoo, Mahmoudvand, Hossein. (1404). 'Seroprevalence and Associated Risk Factors of Toxocariasis in Children With Hypereosinophilia in Iran', سامانه مدیریت نشریات علمی, 80(6), pp. 1429-1436. doi: 10.66224/ARI.80.6.3403
Raziani, Yosra, Sepahvand, Azadeh, Masoori, Leila, Baharvand, Parastoo, Mahmoudvand, Hossein. Seroprevalence and Associated Risk Factors of Toxocariasis in Children With Hypereosinophilia in Iran. سامانه مدیریت نشریات علمی, 1404; 80(6): 1429-1436. doi: 10.66224/ARI.80.6.3403

Seroprevalence and Associated Risk Factors of Toxocariasis in Children With Hypereosinophilia in Iran

Archives of Razi Institute
مقاله 7، دوره 80، شماره 6، بهمن و اسفند 2025، صفحه 1429-1436    اصل مقاله (671.86 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.66224/ARI.80.6.3403
نویسندگان
Yosra Raziani1؛ Azadeh Sepahvand2؛ Leila Masoori3؛ Parastoo Baharvand4؛ Hossein Mahmoudvand* 3
1Department of Nursing, Al-Mustaqbal University College, Babylon, Iraq.
2Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
3Department of Medical Parasitology and Mycology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
4Department of Community Medicine, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
چکیده
Introduction: Toxocariasis is a significant parasitic disease with a global distribution, caused by two nematodes: Toxocara canis (a parasite of the dog’s small intestine) and Toxocara cati (a parasite of the cat’s small intestine). Eosinophilia, characterized by an elevation in peripheral blood eosinophil counts exceeding 10%, serves as a significant clinical marker for helminthic infections. This study aims to investigate the seroepidemiology of T. canis and its risk factors in children with hypereosinophilia in Lorestan Province, Western Iran.
Materials & Methods: This cross-sectional study was conducted from May 2021 to June 2023, involving a cohort of 300 children aged 2 to 15 years who presented with eosinophilia (>10%) and were referred to healthcare facilities in Lorestan Province. Children who were younger than 12 years (between 2-12 years), had blood eosinophil counts exceeding 10%, and consented to participate in this study were deemed to fulfill the inclusion criteria. The prevalence of toxocariasis was confirmed serologically by detecting human IgG antibodies utilizing commercially available anti-IgG-Toxocara canis kits. Demographic and some risk factors regarding the enrolled subjects, including gender, age, type of residence, consuming unwashed vegetables and fruits, and history of animal contact, were collected.
Results: Out of a total of 300 children with eosinophilia, 35(11.7%) were identified as seropositive for toxocariasis. Specifically, female participants were less likely to contract toxocariasis than male children [P=0.002, OR=0.184 (0.052-0543)]. Additionally, individuals living in urban environments exhibit a 4.54-fold increased likelihood of contracting toxocariasis compared to their rural counterparts [P=0.010, OR=4.546 (1.433-9.419)]. Furthermore, individuals who did not consume unwashed vegetables demonstrated a reduced risk of toxocariasis infection [P=0.001, OR=0.016 (0.005-0.048)]. 
Conclusion: The findings of our study indicated a significant seroprevalence of toxocariasis among children exhibiting eosinophilia in western Iran. This suggests that toxocariasis should be regarded as a potential etiological factor for eosinophilia, particularly in individuals with a history of consuming unwashed fruits and vegetables, as well as those residing in rural regions of Iran.
کلیدواژه‌ها
Enzyme-linked immunosorbent assay (ELISA)؛ Eosinophilia؛ Lorestan؛ Seroepidemiology؛ Toxocara canis
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مراجع
References

  1. Ma G, Holland CV, Wang T, Hofmann A, Fan CK, Maizels RM, et al. Human toxocariasis. Lancet Infect Dis. 2018; 18(1):e14-e24 [DOI:10.1016/S1473-3099(17)30331-6] [PMID]
  2. Hamilton CM, Yoshida A, Pinelli E, Holland CV. Toxocariasis. In: Bruschi F, editor. Helminth Infections and their Impact on Global Public Health. Vienna: Springer; 2014.[DOI:10.1007/978-3-7091-1782-8_14]
  3. Moreira GM, Telmo Pde L, Mendonça M, Moreira AN, McBride AJ, Scaini CJ, et al. Human toxocariasis: Current advances in diagnostics, treatment, and interventions. Trends Parasitol. 2014; 30(9):456-64. [DOI:10.1016/j.pt.2014.07.003] [PMID]
  4. O’Connell EM, Nutman TB. Eosinophilia in infectious diseases. Immunol Allergy Clin North Am. 2015; 35(3):493-522.[DOI:10.1016/j.iac.2015.05.003] [PMID]
  5. Kwon NH, Oh MJ, Lee SP, Lee BJ, Choi DC. The prevalence and diagnostic value of toxocariasis in unknown eosinophilia. Ann Hematol. 2006; 85(4):233-8. [DOI:10.1007/s00277-005-0069-x] [PMID]
  6. Borhani Zarandi M, Hoseini SH, Jalousian F, Etebar F, Vojgani M. Evaluate Toxocara Canis Excretory-Secretory Antigens in Experimental Allergic Encephalomyelitis (EAE). Iran J Vet Med. 2017; 11(2):175-83. [DOI:10.22059/ijvm.2017.61638]
  7. Manshori F, Jalousian F, Hosseini SH, Shayan P, Soltani M. Detecting and identifying wolbachia pipientis in occult dirofilariasis using a high-resolution melting real-time PCR in Stray Dogs. Iran J Vet Med. 2024; 18(4):579-88. [Link]
  8. Eslamirad Z. [Toxocariasis: The Sanitary Hazard in Urban Communities of Iran (Persian)]. J Arak Uni Med Sci. 2018; 21 (3):1-4. [Link]
  9. Abbaszadeh Afshar MJ, Zahabiun F, Heydarian P, Mozafar Saadati H, Mohtasebi S, Khodamoradi F, et al. A systematic review and meta-analysis of toxocariasis in Iran: Is it time to take it seriously? Acta Parasitol. 2020; 65(3):569-84.[DOI:10.2478/s11686-020-00195-1] [PMID]
  10. Weatherhead JE, Hotez PJ. Worm Infections in Children. Pediatr Rev. 2015; 36(8):341-52; quiz 353-4. [DOI:10.1542/pir.36.8.341] [PMID]
  11. Mahmoudvand H, Taee N, Ebrahimzadeh F, Mirhosseini MS, Faraji M. Seroprevalence and risk factors of Toxocara canis infection in children (2-15 years old) referred to health centers of Lorestan province, Iran. J Pediatr Infect Dis. 2018; 13(01):020-4. [DOI:10.1055/s-0037-1604325]
  12. Sarkari B, Lari M, Shafiei R, Sadjjadi SM. A comparative seroprevalence study of toxocariasis in hypereosinophilic and apparently healthy individuals. Arch Pediatr Infect Dis. 2015; 3(2):e17911. [Link]
  13. Mosayebi M, Hajihossein R, Didehdar M, Eslamirad Z, Ejtehadifar M, Hamzelo Z. The role of Toxocara larva migransin hypereosinophilia with unknown origin in patients referred to laboratories. J Kermanshah Univ Med Sci. 2014; 18(3):e74156. [DOI:10.22110/jkums.v18i3.1543.]
  14. Sadjjadi SM, Khosravi M, Mehrabani D, Orya A. Seroprevalence of Toxocara infection in school children in Shiraz, southern Iran. J Trop Pediatr. 2000; 46(06):327-330. [DOI:10.1093/tropej/46.6.327] [PMID]
  15. Akhlaghi L, Ourmazdi H, Sarafnia A, Vaziri S, Jadidian K, Leghaii Z. [An investigation on the toxocariasis seroprevalence in children (2-12 years old) from Mahidashtarea of Kermanshah province (2003-2004) (Persian)]. Razi J Med Sci. 2006; 13(52):41-8. [Link]
  16. Ghaffar-Naqnehi AH, Khalili B, Kheiri S. [Seroepidemiology of Toxocara canis infection in 2-14 years old children referred to health care centers of Chaharmahal and Bakhtiari province (Persian)]. J Shahrekord Univ Med Sci. 2016; 17(06):121-9. [Link]
  17. Alavi SM, Hosseini SA, Rahdar M, Salmanzadeh SH, Nikkhuy AR. [Determination of seroprevalence rate of Toxocaracanis in 6-15 years aged rural and urban school children in Ahvaz, Iran (Persian)]. J Jundishapur Univ Med Sci. 2011; 3(72):240-8. [Link]
  18. Abbasi S, Ahmadi Afshar A, Haniloo A. [Prevalence of anti-Toxocara antibodies in children with allergic manifestations referring to allergy clinics in Zanjan (Persian)]. Sci J Kurdistan Univ Med Sci. 2017; 22(2):71-9. [Link]
  19. Song HB, Lee D, Jin Y, Kang J, Cho SH, Park MS, et al. Prevalence of Toxocariasis and Its Risk Factors in Patients with Eosinophilia in Korea. Korean J Parasitol. 2020; 58(4):413-9. [DOI:10.3347/kjp.2020.58.4.413] [PMID]
  20. David Ola-Fadunsin S, Bisola Abdulrauf A, Ganiyu I, Aremu Hussain K, Motunrayo Ambali H, Elelu N. The Intensity of Infection and Public Health Perception of Potentially Zoonotic Intestinal Parasites of Dogs in Kwara Central, Nigeria. Iran J Vet Med. 2023; 17(2):119-28. [DOI:10.32598/IJVM.17.2.1005295]
  21. Namroodi S, Arabkhazaeli F, Miils JN. First Report of Ixodes ricinus and Rhipicephalus turanicus Infestation in Persian Leopard (Panthera Pardus Saxicolor), Golestan National Park, Iran. Iran J Vet Med. 2018; 12(4):381-5. [DOI:10.22059/ijvm.2018.256802.1004896]
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