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Khosravi, Alireza, Pourmoslemi, Shabnam, Moradkhani, Shirin. (1403). Exploring the Chemical Landscape and Biological Potentials of Rosmarinus officinalis Essential Oil: a GC Analysis Approach. سامانه مدیریت نشریات علمی, 13(4), 1137-1148. doi: 10.22034/jmpb.2024.365089.1663
Alireza Khosravi; Shabnam Pourmoslemi; Shirin Moradkhani. "Exploring the Chemical Landscape and Biological Potentials of Rosmarinus officinalis Essential Oil: a GC Analysis Approach". سامانه مدیریت نشریات علمی, 13, 4, 1403, 1137-1148. doi: 10.22034/jmpb.2024.365089.1663
Khosravi, Alireza, Pourmoslemi, Shabnam, Moradkhani, Shirin. (1403). 'Exploring the Chemical Landscape and Biological Potentials of Rosmarinus officinalis Essential Oil: a GC Analysis Approach', سامانه مدیریت نشریات علمی, 13(4), pp. 1137-1148. doi: 10.22034/jmpb.2024.365089.1663
Khosravi, Alireza, Pourmoslemi, Shabnam, Moradkhani, Shirin. Exploring the Chemical Landscape and Biological Potentials of Rosmarinus officinalis Essential Oil: a GC Analysis Approach. سامانه مدیریت نشریات علمی, 1403; 13(4): 1137-1148. doi: 10.22034/jmpb.2024.365089.1663

Exploring the Chemical Landscape and Biological Potentials of Rosmarinus officinalis Essential Oil: a GC Analysis Approach

Journal of Medicinal plants and By-products
مقاله 24، دوره 13، شماره 4، اسفند 2024، صفحه 1137-1148    اصل مقاله (943.17 K)
نوع مقاله: Research Paper
شناسه دیجیتال (DOI): 10.22034/jmpb.2024.365089.1663
نویسندگان
Alireza Khosravi1؛ Shabnam Pourmoslemi2؛ Shirin Moradkhani* 1
1Department of Pharmacognosy, School of Pharmacy, Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
2Department of Pharmaceutics, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran
چکیده
This article presents an analysis of the chemical constituents, antimicrobial efficacy, and antioxidant activity of the essential oil extracted from leaves of Rosmarinus Officinalis, commonly referred to as Rosemary, originating from Hamedan province in Iran. The essential oil was obtained by hydrodistillation method from the sample purchased from the market (LRM) and those cultivated in the university garden (LRU). The research employed Gas Chromatography/Mass Spectrometry (GC/MS) analysis to examine the chemical composition of the obtained essential oils. The antimicrobial efficacy was evaluated by determining the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) via a sequence of microdilutions, while the DPPH assay was used to assess the antioxidant activity. Standard methods determined the ash contents including total ash and acid-insoluable ash. The chemical composition of the essential oils showed some variations. 1,8-cineol, borneol, and camphor were the main components in LRM, while 1,8-cineol and α-pinene were the major constituents of LRU. In the case of microbial tests, LRM showed the best efficacy on Pseudomonas aeroginosae(SA) and LRU had the highest efficacy on Methicillin-resistant Staphylococcus aureus (MRSA). The research exhibited the comparable antioxidant activity of essential oils derived from different plant variations, noting that these activities were not as potent as the positive control. The total ash content of LRM was higher than that of LRU, which indicates impurities in the first sample. The study further explored the variations in these characteristics based on the plant’s conditions (purchased or cultivated). The presence of different components in the essential oils from various sources may contribute to the observed variations in biological properties. The researchers recommend further extensive investigations into the chemical constituents and their relative abundance in R. officinalis essential oil to enhance understanding of its therapeutic potential and industrial applications.
کلیدواژه‌ها
Rosemary؛ Chemical Composition؛ Antioxidant؛ Antimicrobe؛ Volatile oil
مراجع
  1. Rajaee Maleki S. The In Vitro Inhibitory Effects of the Rosemary Essential Oil on Some Gram Positive and Negative Bacteria. J Ilam Uni Med Sci. 2016;24(2):80-9.
  2. Uritu C.M,, Mihai C.T., Stanciu G.D., Dodi G., Alexa-Stratulat T., Luca A., et al. Medicinal plants of the family Lamiaceae in pain therapy: A review. Pain Res. Manage. 2018.
  3. De Oliveira J.R., Camargo S.E.A., De Oliveira L.D. Rosmarinus officinalis L.(rosemary) as therapeutic and prophylactic agent. J. Biomedical Sci. 2019;26(1):1-22.
  4. Rašković A., Milanović I., Pavlović N., Ćebović T., Vukmirović S., Mikov M. Antioxidant activity of rosemary (Rosmarinus officinalis L.) essential oil and its hepatoprotective potential. BMC Complement. Alternative Med. 2014;14(1):1-9.
  5. Vahdat S.M., Khavarpour M., Kazemi S. Chemical Composition, Antimicrobial and Analgesic Properties of Rosmarinus officinalis L. from North of Iran. J. Med. Plants By-Prod. 2020;9(Special):107-14.
  6. Michalak M. Aromatherapy and methods of applying essential oils. Archives of Physiotherapy and Global Res. 2018;22(2):25-31.
  7. Jaimand K., Rezaee M.B., Mirza M., Nadery M., Karimi S., Ashtiany S., et al. Optimization of essential oil extraction conditions for Rosmarinus officinalis L. on a laboratory and semi-industrial scale. J. Med. Plants By-Prod. 2020;9(Special):29-34.
  8. Serralutzu F., Stangoni A., Amadou B., Tijan D., Re G.A., Marceddu S., et al. Essential oil composition and yield of a Rosmarinus officinalis L. natural population with an extended flowering season in a coastal Mediterranean environment and perspectives for exploitations. Gen. Resources and Crop Evolution. 2020;67(7):1777-93.
  9. Bozin B., Mimica-Dukic N., Samojlik I., Jovin E. Antimicrobial and antioxidant properties of rosemary and sage (Rosmarinus officinalis L. and Salvia officinalis L., Lamiaceae) essential oils. J. Agric. Food Chem. 2007;55(19):7879-85.
  10. Wang W., Li N., Luo M., Zu Y., Efferth T. Antibacterial activity and anticancer activity of Rosmarinus officinalis L. essential oil compared to that of its main components. Molecules. 2012;17(3):2704-13.
  11. Hyldgaard M., Mygind T., Meyer R.L. Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components. Frontiers in Microbiology. 2012;3:12.
  12. Abdullah B.H., Hatem S.F., Jumaa W. A comparative study of the antibacterial activity of clove and rosemary essential oils on multidrug resistant bacteria. Pharmac. Biosci. J. 2015:18-22.
  13. Rossi M., Torri D., De Geeter S., Cremer C., Poesen J. Topographic thresholds for gully head formation in badlands. Earth Surface Processes and Landforms. 2022;47(15):3558-87.
  14. Mozaffarian V. A dictionary of Iranian plant names. Tehran: Farhang Moaser. 1996;396:396-8.
  15. Mojab F., Khalaj N. Chemical Constituents of the Essential Oil of Stachys fruticulosa M. Bieb. From Iran. Avicenna J. Pharma Res. 2020;1(1):33-6.
  16. Taherkhani A., Khamverdi Z., Sayafi M., Moradkhani S. Investigation on Chemical Constituents of Foeniculum vulgare Essential Oil and the Molecular Docking Studies of its Components for Possible Matrix Metalloproteinase-13 Inhibition. Avicenna J. Pharma. Res. 2020;1(2):65-71.
  17. Bahramloo M., Moradkhani S., Sedaghat Hamedani M. Phytochemical evaluation and antioxidant effects of the essential oil and distillates of Nepeta crispa Willd. J. Med. Plants. 2023;22(86):27-43.
  18. Motaghed M., Nili-Ahmadabadi A., Moradkhani S. Assessment of the anti-oxidative potential of Nepeta crispa Willd.(Lamiaceae) and its effects on oxidative stability of virgin sunflower oil under accelerated storage conditions. J. Med. Plants. 2022;21(82):13-27.
  19. Francomano F., Caruso A., Barbarossa A., Fazio A., La Torre C., Ceramella J., et al. β-Caryophyllene: a sesquiterpene with countless biological properties. Applied Sci. 2019;9(24):5420.
  20. Surendran S., Qassadi F., Surendran G., Lilley D., Heinrich M. Myrcene what are the potential health benefits of this flavouring and aroma agent? Frontiers In Nutrition. 2021;8:699666.
  21. Quiroga P.R., Nepote V., Baumgartner M.T. Contribution of organic acids to α-terpinene antioxidant activity. Food Chem. 2019;277:267-72.
  22. Pirbalouti A.G., Mohamadpoor H., Bajalan I., Malekpoor F. Chemical compositions and antioxidant activity of essential oils from inflorescences of two landraces of hyssop [Hyssopus officinalis L. subsp. angustifolius (Bieb.)] cultivated in Southwestern, Iran. J. Essential Oil Bearing Plants. 2019;22(4):1074-81.
  23. Garzoli S., Božović M., Baldisserotto A., Sabatino M., Cesa S., Pepi F., et al. Essential oil extraction, chemical analysis and anti-Candida activity of Foeniculum vulgare Miller–new approaches. Natural Prod. Res. 2018;32(11):1254-9.
  24. Zhang H.Y., Gao Y., Lai P.X. Chemical composition, antioxidant, antimicrobial and cytotoxic activities of essential oil from Premna microphylla Turczaninow. Molecules. 2017;22(3):381.
  25. Willrodt C., Halan B., Karthaus L., Rehdorf J., Julsing M.K., Buehler K., Schmid A. Continuous multistep synthesis of perillic acid from limonene by catalytic biofilms under segmented flow. Biotechnol. Bioengin. 2017;114(2):281-90.
  26. Satoh M., Kusumoto N., Matsui N., Makino R., Hashida K., Arai D., et al. Antitermitic and antifungal properties of enantiopure linalool and furanoid linalool oxide confirmed in Lindera umbellata var. membranacea. J. Wood Chem. Technol. 2022;42(1):37-45.
  27. Hcini K., Sotomayor J.A., Jordán M.J., Bouzid S. Chemical composition of the essential oil of Rosemary (Rosmarinus officinalis L.) of Tunisian origin. Asian J. Chem. 2013;25(5):2601.
  28. Sienkiewicz M., Łysakowska M., Pastuszka M., Bienias W., Kowalczyk E. The potential of use basil and rosemary essential oils as effective antibacterial agents. Molecules. 2013;18(8):9334-51.
  29. Jiang Y., Wu N., Fu Y.J., Wang W., Luo M., Zhao C.J., et al. Chemical composition and antimicrobial activity of the essential oil of Rosemary. Envir. Toxic. Pharmacol. 2011;32(1):63-8.
  30. Bendeddouche M.S., Benhassaini H., Hazem Z., Romane A. Essential oil analysis and antibacterial activity of Rosmarinus tournefortii from Algeria. Natural Prod. Communications. 2011;6(10):1934578X1100601026.
  31. Ladan Moghadam A.R. Antioxidant activity and chemical composition of Rosmarinus officinalis L. essential oil from Iran. J. Essential Oil Bearing Plants. 2015;18(6):1490-4.
  32. Moghtader M., Afzali D. Study of the antimicrobial properties of the essential oil of Rosemary. American-Eurasian J. Agric. Envir Sci. 2009;5(3):393-7.
  33. Touafek O., Nacer A., Kabouche A., Kabouche Z., Bruneau C. Chemical composition of the essential oil of Rosmarinus officinalis cultivated in the Algerian Sahara. Chem. Natural Compounds. 2004;40:28-9.
  34. Chalchat J.C., Özcan M.M. Comparative essential oil composition of flowers, leaves and stems of basil (Ocimum basilicum L.) used as herb. Food Chem. 2008;110(2):501-3.
  35. Wannes W.A., Mhamdi B., Marzouk B. Variations in essential oil and fatty acid composition during Myrtus communis var. italica fruit maturation. Food Chem. 2009;112(3):621-6.
  36. Santoyo S., Cavero S., Jaime L., Ibanez E., Senorans F., Reglero G. Chemical composition and antimicrobial activity of Rosmarinus officinalis L. essential oil obtained via supercritical fluid extraction. J. Food Protect. 2005;68(4):790-5.
  37. Adel K., Zied Z., Ines B.C., Ahmed B., Neji G., Mohamed D., Radhouane G. Chemical constituents and antioxidant properties of Rosmarinus officinalis L. essential oil cultivated from the South-Western of Tunisia. J. Med. Plants Res. 2011;5(29):6502-8.
  38. Lo Presti M., Ragusa S., Trozzi A., Dugo P., Visinoni F., Fazio A., et al. A comparison between different techniques for the isolation of rosemary essential oil. J. Separation Sci. 2005;28(3):273-80.
  39. Mihajilov-Krstev T., Radnović D., Kitić D., Stojanović-Radić Z., Zlatković B. Antimicrobial activity of Satureja hortensis L. essential oil against pathogenic microbial strains. Arch. Biologic. Sci. 2010;62(1):159-66.
  40. Prabuseenivasan S., Jayakumar M., Ignacimuthu S. In vitro antibacterial activity of some plant essential oils. BMC Complementary and Alternative Med. 2006;6(1):1-8.
  41. Zaouali Y., Bouzaine T., Boussaid M. Essential oils composition in two Rosmarinus officinalis L. varieties and incidence for antimicrobial and antioxidant activities. Food and Chem. Toxic. 2010;48(11):3144-52.
  42. Bajpai V.K., Baek K.H., Kang S.C. Control of Salmonella in foods by using essential oils: A review. Food Res. Int. 2012;45(2):722-34.
  43. Tornuk F., Cankurt H., Ozturk I., Sagdic O., Bayram O., Yetim H. Efficacy of various plant hydrosols as natural food sanitizers in reducing Escherichia coli O157: H7 and Salmonella Typhimurium on fresh cut carrots and apples. Int. J. Food Micro. 2011;148(1):30-5.
  44. Teixeira B., Marques A., Ramos C., Neng N.R., Nogueira J.M., Saraiva J.A., Nunes M.L. Chemical composition and antibacterial and antioxidant properties of commercial essential oils. Indust. Crops and Prod. 2013;43:587-95.
  45. Ben Jemia M., Tundis R., Pugliese A., Menichini F., Senatore F., Bruno M., et al. Effect of bioclimatic area on the composition and bioactivity of Tunisian Rosmarinus officinalis essential oils. Natural Prod. Res. 2015;29(3):213-22.
  46. Keramat M., Golmakani M.T, Aminlari M., Alavi N., Nowroozi M., Shekarforoush SH. Investigation the oxidative stability of virgin olive oil by using rosemary (Rosmarinus officinalis) essential oil. Iran. J. Food Sci. Tech. 2017;13(60):157-172.
  47. Christopoulou S.D., Androutsopoulou C., Hahalis P., Kotsalou C., Vantarakis A., Lamari F.N. Rosemary Extract and essential oil as drink ingredients: an evaluation of their chemical composition, genotoxicity, antimicrobial, antiviral, and antioxidant properties. Foods. 2021;10(12):3143.
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