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Ahmed Abed, A, Khudair Kalaf, A. (1402). Serological Detection for Toxoplasmosis among Patients with Covid-19 in Thi-Qar Province. سامانه مدیریت نشریات علمی, 78(2), 675-680. doi: 10.22092/ari.2022.359481.2432
A Ahmed Abed; A Khudair Kalaf. "Serological Detection for Toxoplasmosis among Patients with Covid-19 in Thi-Qar Province". سامانه مدیریت نشریات علمی, 78, 2, 1402, 675-680. doi: 10.22092/ari.2022.359481.2432
Ahmed Abed, A, Khudair Kalaf, A. (1402). 'Serological Detection for Toxoplasmosis among Patients with Covid-19 in Thi-Qar Province', سامانه مدیریت نشریات علمی, 78(2), pp. 675-680. doi: 10.22092/ari.2022.359481.2432
Ahmed Abed, A, Khudair Kalaf, A. Serological Detection for Toxoplasmosis among Patients with Covid-19 in Thi-Qar Province. سامانه مدیریت نشریات علمی, 1402; 78(2): 675-680. doi: 10.22092/ari.2022.359481.2432

Serological Detection for Toxoplasmosis among Patients with Covid-19 in Thi-Qar Province

Archives of Razi Institute
مقاله 22، دوره 78، شماره 2، خرداد و تیر 2023، صفحه 675-680    اصل مقاله (364.87 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.359481.2432
نویسندگان
A Ahmed Abed؛ A Khudair Kalaf*
College of Medicine, Department of Microbiology, University of Thi-Qar, Thi-Qar, Iraq
چکیده
Covid-19 is a viral disease that affects humans caused by a type of virus belonging to the family Coronaviridae called the SARS-CoV-2 virus. The parasitic infection associated with this disease affects the host's immune response regulation. The levels of IgG and IgM of Toxoplasma gondii in the serum of patients with COVID-19 were measured by immunoassay of the patient’s sera by ELISA. Also, the level of interferon-gamma (IFN-γ) in a covid-19 patient with or without Toxoplasmosis was evaluated. 120 samples were collected, 60 were positive for COVID-19, confirmed by clinically and radiographic examination, and 30 were in the control group. The results showed a significant difference between the infection with Covid-19 and T. gondii during the chronic phase of Toxoplasmosis compared to the negative relationship in the acute phase. The results of INF-γ levels among Covid-19 patients were positive for all samples included in the test (30 Covid-19 patients and 30 patients COVID-19(+)/T. gondii IgG) compared to the control group. The chronic form of Toxoplasma disease, due to change in the production of this interferon, the COVID-19 infection has changed.
کلیدواژه‌ها
Toxoplasma gondii؛ interferon gamma؛ immune response؛ COVID-19
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مراجع
  1. El Zowalaty ME, Jarhult JD. From SARS to COVID-19: A previously unknown SARS- related coronavirus (SARS-CoV-2) of pandemic potential infecting humans - Call for a One Health approach. One Health. 2020;9:100124.
  2. Yang L, Liu S, Liu J, Zhang Z, Wan X, Huang B, et al. COVID-19: immunopathogenesis and Immunotherapeutics. Signal Transduct Target Ther. 2020;5(1):128.
  3. Hemphill A, Muller N, Muller J. Comparative Pathobiology of the Intestinal Protozoan Parasites Giardia lamblia, Entamoeba histolytica, and Cryptosporidium parvum. Pathogens. 2019;8(3).
  4. Lima TS, Lodoen MB. Mechanisms of Human Innate Immune Evasion by Toxoplasma gondii. Front Cell Infect Microbiol. 2019;9:103.
  5. Jankowiak L, Rozsa L, Tryjanowski P, Moller AP. A negative covariation between toxoplasmosis and CoVID-19 with alternative interpretations. Sci Rep. 2020;10(1):12512.
  6. Suzuki Y, Sa Q, Gehman M, Ochiai E. Interferon-gamma- and perforin-mediated immune responses for resistance against Toxoplasma gondii in the brain. Expert Rev Mol Med. 2011;13:31.
  7. Abdel-Hamed EF, Ibrahim MN, Mostafa NE, Moawad HSF, Elgammal NE, Darwiesh EM, et al. Role of interferon gamma in SARS-CoV-2-positive patients with parasitic infections. Gut Pathog. 2021;13(1):29.
  8. Chinese Center For Disease C, Prevention. Technical Guidelines for COVID-19 Laboratory Testing. China CDC Wkly. 2020;2(19):332-6.
  9. Kiyoyama T, Tokuda Y, Shiiki S, Hachiman T, Shimasaki T, Endo K. Isopropyl alcohol compared with isopropyl alcohol plus povidone-iodine as skin preparation for prevention of blood culture contamination. J Clin Microbiol. 2009;47(1):54-8.
  10. Roozenbeek J, Schneider CR, Dryhurst S, Kerr J, Freeman ALJ, Recchia G, et al. Susceptibility to misinformation about COVID-19 around the world. R Soc Open Sci. 2020;7(10):201199.
  11. Woolf SH, Masters RK, Aron LY. Effect of the covid-19 pandemic in 2020 on life expectancy across populations in the USA and other high income countries: simulations of provisional mortality data. BMJ. 2021;373:n1343.
  12. Salyer SJ, Maeda J, Sembuche S, Kebede Y, Tshangela A, Moussif M, et al. The first and second waves of the COVID-19 pandemic in Africa: a cross-sectional study. Lancet. 2021;397(10281):1265-75.
  13. Saeed BQ, Al-Shahrabi R, Bolarinwa OA. Socio-demographic correlate of knowledge and practice toward COVID-19 among people living in Mosul-Iraq: A cross-sectional study. PLoS One. 2021;16(3):e0249310.
  14. Darweesh O, Abdulrazzaq GM, Al-Zidan RN, Bebane P, Merkhan M, Aldabbagh R, et al. Evaluation of the Pharmacologic Treatment of COVID-19 Pandemic in Iraq. Curr Pharmacol Rep. 2021;7(4):171-8.
  15. Hashim BM, Al-Naseri SK, Al Maliki A, Sa’adi Z, Malik A, Yaseen ZM. On the investigation of COVID-19 lockdown influence on air pollution concentration: regional investigation over eighteen provinces in Iraq. Environ Sci Pollut Res. 2021;28(36):50344-62.
  16. Ghaffari S, Kalantari N, Gorgani-Firouzjaee T, Bayani M, Jalali F, Daroonkola MA. Is COVID-19 associated with latent toxoplasmosis? Environ Sci Pollut Res Int. 2021;28(47):67886-90.
  17. Wolday D, Gebrecherkos T, Arefaine ZG, Kiros YK, Gebreegzabher A, Tasew G, et al. Effect of co-infection with intestinal parasites on COVID-19 severity: A prospective observational cohort study. EClinicalMedicine. 2021;39:101054.
  18. Yamamoto M, Okuyama M, Ma JS, Kimura T, Kamiyama N, Saiga H, et al. A cluster of interferon-gamma-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii. Immunity. 2012;37(2):302-13.
  19. Rudzinski M, Pardini L, Bernstein M, More G, Khoury M, Duarte SC, et al. Interferon-gamma and IL-10 Release Assay for Patients with Ocular Toxoplasmosis. Am J Trop Med Hyg. 2020;103(6):2239-43.
  20. Bando H, Lee Y, Sakaguchi N, Pradipta A, Sakamoto R, Tanaka S, et al. Toxoplasma Effector GRA15-Dependent Suppression of IFN-gamma-Induced Antiparasitic Response in Human Neurons. Front Cell Infect Microbiol. 2019;9:140.
  21. Gimenez E, Albert E, Torres I, Remigia MJ, Alcaraz MJ, Galindo MJ, et al. SARS-CoV-2-reactive interferon-gamma-producing CD8+ T cells in patients hospitalized with coronavirus disease 2019. J Med Virol. 2021;93(1):375-82.
  1. Radke JB, Carey KL, Shaw S, Metkar SR, Mulrooney C, Gale JP, et al. High Throughput Screen Identifies Interferon gamma-Dependent Inhibitors of Toxoplasma gondii Growth. ACS Infect Dis. 2018;4(10):1499-507.
  2. Ward JD, Cornaby C, Schmitz JL. Indeterminate QuantiFERON Gold Plus Results Reveal Deficient Interferon Gamma Responses in Severely Ill COVID-19 Patients. J Clin Microbiol. 2021;59(10):e0081121.
  3. Rogers KJ, Shtanko O, Vijay R, Mallinger LN, Joyner CJ, Galinski MR, et al. Acute Plasmodium Infection Promotes Interferon-Gamma-Dependent Resistance to Ebola Virus Infection. Cell Rep. 2020;30(12):4041-51.
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