اخبار و اعلانات

 آمار

تعداد نشریات282
تعداد نشریات سازمان80
تعداد شماره‌ها3,272
تعداد مقالات36,149
تعداد مشاهده مقاله55,722,610
تعداد دریافت فایل اصل مقاله94,500,131
Abd AL-Zahra Ali, R, Rasmi Huwait, A. J, Issa Abed, R, Faisal Majeed, M. (1402). The Histopathological and Oxidative Stress Profiles in Japanese Quails (Coturnix japonica) Induced by Dietary Lead. سامانه مدیریت نشریات علمی, 78(2), 523-530. doi: 10.22092/ari.2022.359352.2407
R Abd AL-Zahra Ali; A. J Rasmi Huwait; R Issa Abed; M Faisal Majeed. "The Histopathological and Oxidative Stress Profiles in Japanese Quails (Coturnix japonica) Induced by Dietary Lead". سامانه مدیریت نشریات علمی, 78, 2, 1402, 523-530. doi: 10.22092/ari.2022.359352.2407
Abd AL-Zahra Ali, R, Rasmi Huwait, A. J, Issa Abed, R, Faisal Majeed, M. (1402). 'The Histopathological and Oxidative Stress Profiles in Japanese Quails (Coturnix japonica) Induced by Dietary Lead', سامانه مدیریت نشریات علمی, 78(2), pp. 523-530. doi: 10.22092/ari.2022.359352.2407
Abd AL-Zahra Ali, R, Rasmi Huwait, A. J, Issa Abed, R, Faisal Majeed, M. The Histopathological and Oxidative Stress Profiles in Japanese Quails (Coturnix japonica) Induced by Dietary Lead. سامانه مدیریت نشریات علمی, 1402; 78(2): 523-530. doi: 10.22092/ari.2022.359352.2407

The Histopathological and Oxidative Stress Profiles in Japanese Quails (Coturnix japonica) Induced by Dietary Lead

Archives of Razi Institute
مقاله 4، دوره 78، شماره 2، خرداد و تیر 2023، صفحه 523-530    اصل مقاله (521.36 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.359352.2407
نویسندگان
R Abd AL-Zahra Ali* 1؛ A. J Rasmi Huwait2؛ R Issa Abed3؛ M Faisal Majeed2
1Department of Pathology and Poultry Disease, Faculty of Veterinary Medicine, University of Basrah, Basrah, Iraq
2Department of Anatomy and Histology, Faculty of Veterinary Medicine, University of Basrah, Basrah, Iraq
3Department of Clinical Laboratory Sciences, Faculty of Pharmacy, University of Basrah, Basrah, Iraq
چکیده
In their native habitat, avians are exposed to external toxicity factors, the most prominent of which are chemical lead compounds that threaten human and animal health. The goal of this investigation was to estimate the adverse effects of lead acetate (Pb(CH3COO)2 (H2O)3) on the health status of Japanese quail (Coturnix japonica). 18 adult male Japanese quails (Coturnix coturnix japonica) were employed in this investigation. After two weeks of acclimatization, the birds were randomly divided into three groups: the control group received no Pb+2, the Low Dose Group received 50 mg/kg of Pb+2 as lead acetate Pb(CH3COO)2 (H2O)3 in the diet, and the High Dose Group received 100 mg/kg of Pb+2 as lead acetate Pb(CH3COO)2(H2O)3 in the diet, for 30 days. Results showed that the Pb bioaccumulation was recorded at the highest values in the liver compared with the kidney, and as expected, the ranges of the lead accumulation were significantly higher in the animals who received 100 mg/kg Pb compared with animals who received 50 mg/kg Pb and the control group. In the high dose group, serum content showed significantly increased levels (P≤0.05) of aminotransferase enzymes (ALT and AST ), glucose, creatinine, and uric acid levels compared to other groups, while antioxidant enzymes (CAT, GSH, and GSH-PX) levels in the liver and kidney were significantly reduced (P≤0.05). The results showed that the MDA appeared to be significantly increasing (P≤0.05) in the high dose group compared to the other groups. Compared to the low dose and control groups, the high dosage group produced substantial histological abnormalities in the liver and kidney.
کلیدواژه‌ها
Dietary Lead Toxicity؛ Coturnix Japonica؛ Liver؛ Kidney
سایر فایل های مرتبط با مقاله
مراجع
  1. Abbasi NA, Jaspers VL, Chaudhry MJ, Ali S, Malik RN. Influence of taxa, trophic level, and location on bioaccumulation of toxic metals in bird's feathers: a preliminary biomonitoring study using multiple bird species from Pakistan. Chemosphere. 2015;120:527-37.
  2. Flora SJS, Flora G, Saxena G. Chapter 4 - Environmental occurrence, health effects and management of lead poisoning. In: Casas JS, Sordo J, editors. Lead. Amsterdam: Elsevier Science B.V.; 2006. p. 158-228.
  3. Pearce JM. Burton's line in lead poisoning. Eur Neurol. 2007;57(2):118-9.
  4. Flora SJ. Arsenic-induced oxidative stress and its reversibility. Free Radic Biol Med. 2011;51(2):257-81.
  5. Flora SJS. Nutritional Components Modify Metal Absorption, Toxic Response and Chelation Therapy. J Nutr Environ Med. 2002;12(1):53-67.
  6. Burger J, Gochfeld M. Habitat, population dynamics, and metal levels in colonial waterbirds: a food chain approach: CRC Press; 2016.
  7. Larsen K. Creatinine assay by a reaction-kinetic principle. Clin Chim Acta. 1972;41:209-17.
  8. Bulgar HA, Johns HE. The determination of plasma uric acid. J Biol Chem. 1941;140:427.
  9. Kalckar HM. Differential spectrophotometry of purine compounds by means of specific enzymes; determination of hydroxypurine compounds. J Biol Chem. 1947;167(2):429-43.
  10. Goth L. A simple method for determination of serum catalase activity and revision of reference range. Clin Chim Acta. 1991;196(2-3):143-51.
  11. Lawrence RA, Burk RF. Glutathione peroxidase activity in selenium-deficient rat liver. Biochem Biophys Res Commun. 1976;71(4):952-8.
  12. Sedlak J, Lindsay RH. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem. 1968;25(1):192-205.
  13. Placer ZA, Cushman LL, Johnson BC. Estimation of product of lipid peroxidation (malonyl dialdehyde) in biochemical systems. Anal Biochem. 1966;16(2):359-64.
  14. Luna LG. Manual of histologic staining methods of the Armed Forces Institute of Pathology. 3rd ed. New York: McGraw-Hill; 1968.
  15. Qu W, Du GL, Feng B, Shao H. Effects of oxidative stress on blood pressure and electrocardiogram findings in workers with occupational exposure to lead. J Int Med Res. 2019;47(6):2461-70.
  16. Richardson JA. Implications of toxic substances in clinical disorders. In: Harrison G, Lightfoot T, editors. Clinical Avian Medicine: Palm Beach, FL: Spix Publishing; 2006. p. 713-5.
  17. Patra RC, Rautray AK, Swarup D. Oxidative stress in lead and cadmium toxicity and its amelioration. Vet Med Int. 2011;2011:457327.
  18. Alijagic A, Islamagic E, Focak M, Suljevic D. Effects of trivalent and hexavalent dietary chromium on blood biochemical profile in Japanese quails. Bulg J Vet Med. 2018;21(4).
  19. Suljevic D, Islamagic E, Corbic A, Focak M, Filipic F. Chronic cadmium exposure in Japanese quails perturbs serum biochemical parameters and enzyme activity. Drug Chem Toxicol. 2020;43(1):37-42.
  20. Suljevic D, Handzic N, Focak M, Lasic I, Sipovic F, Sulejmanovic J, et al. Lead Exposure Influences Serum Biomarkers, Hepatocyte Survival, Bone Marrow Hematopoiesis, and the Reproductive Cycle in Japanese Quails. Biol Trace Elem Res. 2021;199(4):1574-83.
  21. Wong DL, Merrifield-MacRae ME, Stillman MJ. Lead(II) Binding in Metallothioneins. In: Astrid S, Helmut S, Roland KOS, editors. Lead: Its Effects on Environment and Health. Berlin, Boston: De Gruyter; 2017. p. 241-70.
  22. Hamidipour F, Pourkhabbaz H, Banaee M, Javanmardi S. Bioaccumulation of Lead in the Tissues of Japanese Quails and Its Effects on Blood Biochemical Factors. Iran J Toxicol. 2016;10(2):13-21.
  23. Alagawany M, Abd El-Hack ME, Farag MR, Elnesr SS, El-Kholy MS, Saadeldin IM, et al. Dietary supplementation of Yucca schidigera extract enhances productive and reproductive performances, blood profile, immune function, and antioxidant status in laying Japanese quails exposed to lead in the diet. Poult Sci. 2018;97(9):3126-37.
  24. Moussa Z, Judeh ZMA, Ahmed SA. Non-enzymatic exogenous and endogenous antioxidants. In: Das K, Das S, Biradar MS, Bobbarala V, Tata SS, editors. Free Radical Medicine and Biology. 2020.
  25. Kou H, Ya J, Gao X, Zhao H. The effects of chronic lead exposure on the liver of female Japanese quail (Coturnix japonica): Histopathological damages, oxidative stress and AMP-activated protein kinase based lipid metabolism disorder. Ecotoxicol Environ Saf. 2020;190:110055.
  26. Almasmoum H, Refaat B, Ghaith MM, Almaimani RA, Idris S, Ahmad J, et al. Protective effect of Vitamin D3 against lead induced hepatotoxicity, oxidative stress, immunosuppressive and calcium homeostasis disorders in rat. Environ Toxicol Pharmacol. 2019;72:103246.
  1. Liu HN, Liu Y, Hu LL, Suo YL, Zhang L, Jin F, et al. Effects of dietary supplementation of quercetin on performance, egg quality, cecal microflora populations, and antioxidant status in laying hens. Poult Sci. 2014;93(2):347-53.
  2. Yuan C, Song HH, Jiang YJ, Azzam MMM, Zhu S, Zou XT. Effects of lead contamination in feed on laying performance, lead retention of organs and eggs, protein metabolism, and hormone levels of laying hens. J Appl Poult Res. 2013;22(4):878-84.
  3. Johar D, Roth JC, Bay GH, Walker JN, Kroczak TJ, Los M. Inflammatory response, reactive oxygen species, programmed (necrotic-like and apoptotic) cell death and cancer. Rocz Akad Med Bialymst. 2004;49:31-9.
  4. Nehru B, Kaushal S. Alterations in the hepatic enzymes following experimental lead poisoning. Biol Trace Elem Res. 1993;38(1):27-34.
  5. Neyrinck A. Modulation of Kupffer cell activity: physio-pathological consequences on hepatic metabolism. Bull Mem Acad R Med Belg. 2004;159(5-6):358-66.
آمار
تعداد مشاهده مقاله: 300,583
تعداد دریافت فایل اصل مقاله: 18,601


counter
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب