اخبار و اعلانات

 آمار

تعداد نشریات284
تعداد نشریات سازمان82
تعداد شماره‌ها3,081
تعداد مقالات34,377
تعداد مشاهده مقاله48,001,589
تعداد دریافت فایل اصل مقاله78,922,147
Kareem Raheem, Z, Abdulhamid Said, L. (1401). Antibiotic Susceptibility Profile of Bacteria Causing Aerobic Vaginitis in Women in Iraq. سامانه مدیریت نشریات علمی, 78(1), 31-43. doi: 10.22092/ari.2022.358775.2307
Z Kareem Raheem; L Abdulhamid Said. "Antibiotic Susceptibility Profile of Bacteria Causing Aerobic Vaginitis in Women in Iraq". سامانه مدیریت نشریات علمی, 78, 1, 1401, 31-43. doi: 10.22092/ari.2022.358775.2307
Kareem Raheem, Z, Abdulhamid Said, L. (1401). 'Antibiotic Susceptibility Profile of Bacteria Causing Aerobic Vaginitis in Women in Iraq', سامانه مدیریت نشریات علمی, 78(1), pp. 31-43. doi: 10.22092/ari.2022.358775.2307
Kareem Raheem, Z, Abdulhamid Said, L. Antibiotic Susceptibility Profile of Bacteria Causing Aerobic Vaginitis in Women in Iraq. سامانه مدیریت نشریات علمی, 1401; 78(1): 31-43. doi: 10.22092/ari.2022.358775.2307

Antibiotic Susceptibility Profile of Bacteria Causing Aerobic Vaginitis in Women in Iraq

Archives of Razi Institute
مقاله 7، دوره 78، شماره 1، فروردین و اردیبهشت 2023، صفحه 31-43    اصل مقاله (765.55 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.358775.2307
نویسندگان
Z Kareem Raheem* ؛ L Abdulhamid Said
Department of Biology, College of Science, Al-Mustansiriyah University, Baghdad, Iraq
چکیده
Aerobic vaginitis (AV) is a vaginal infectious condition characterized by abnormal vaginal discharge, high inflammatory response, signs of epithelial atrophy, an increase in aerobic bacteria of intestinal origin and a decrease in the normal flora, especially Lactobacillus spp.. It is one of the most common reproductive tract infections among women. This study aimed to analyze the antimicrobial susceptibility levels of the dominant bacterial species found in the vaginae of women infected with AV. A total of 89 high vaginal swabs (HVS) were collected from women aged (18-50) years old attending some hospitals and private gynaecology clinics in Baghdad City. All obtained swabs were cultured on different culture media, and the primary diagnosis was performed according to standard laboratory diagnosis protocols. To confirm the diagnosis and to determine the antibiotic susceptibility profile of bacterial isolates, VITEK 2 Compact Automated System GP and GN colourimetric identification cards and AST GN and AST GP cards were used according to Manufacturer Company constructions (BioMérieux / France). Out of 89swabs, ninety-five pathogenic strains were obtained, including 62 isolates (65.2%), Grampositive and 33 isolates (34.7%), Gram-negative bacteria. Staphylococcus spp. (46.3%) The most represented active strain was Escherichia coli (15.7%). All Gram-positive bacterial strains displayed the highest resistance rates (100%) toward penicillins and cephalosporins, while the highest sensitivity rates were toward daptomycin, followed by vancomycin and gentamicin (P=0.001). Gram-negative bacteria displayed the highest resistance rates toward penicillins, beta-lactam combination, monobactam and cephalosporins, while the highest sensitivity rates were toward amikacin followed by imipenem meropenem and gentamicin (P=0.001). It is worth mentioning that Gram-positive bacteria showed 100% sensitivity toward tigecycline. Thirty-eight (40 %) of all obtained bacterial strains were extensively drug-resistant XDR, 57 (60%) were multidrug resistance MDR and no pan-drug resistance PDR was reported. Gram-positive bacteria include 21% XDR and 44.2% MDR strains, while Gram-negative bacteria include 18.9% XDR and 15.7% MDR strains.
کلیدواژه‌ها
Aerobic vaginitis؛ VITEK 2 system؛ GP and GN colourimetric cards؛ Aerobic bacteria؛ Antibiotic susceptibility؛ AST GP and AST GN cards؛ Iraq
سایر فایل های مرتبط با مقاله
مراجع
  1. Li T, Liu Z-H, Li K, Bai H-H. Evaluation of the vaginal microbiome in clinical diagnosis and management of vaginal infectious diseases. Chin Med J. 2019;132(09):1100-3.
  2. Donders GG, Vereecken A, Bosmans E, Dekeersmaecker A, Salembier G, Spitz B. Definition of a type of abnormal vaginal flora that is distinct from bacterial vaginosis: aerobic vaginitis. BJOG. 2002;109(1):34-43.
  3. Gardner HL. Desquamative inflammatory vaginitis: a newly defined entity. Am J Obstet Gynecol. 1968;102(8):1102-5.
  4. Petricevic L, Domig KJ, Nierscher FJ, Sandhofer MJ, Fidesser M, Krondorfer I, et al. Characterisation of the vaginal Lactobacillus microbiota associated with preterm delivery. Sci Rep. 2014;4(1):1-6.
  5. Donders GG, Bellen G, Grinceviciene S, Ruban K, Vieira-Baptista P. Aerobic vaginitis: no longer a stranger. Res Microbiol. 2017;168(9-10):845-58.
  6. Čuržik D, Dražančić A, Hrgović Z. Nonspecific aerobic vaginitis and pregnancy. Fetal Diagn The. 2001;16(3):187-92.
  7. Lamont R, Taylor‐Robinson D. The role of bacterial vaginosis, aerobic vaginitis, abnormal vaginal flora and the risk of preterm birth. BJOG. 2010;117(1):119-20.
  8. Rezeberga D, Lazdane G, Kroica J, Sokolova L, Donders GG. Placental histological inflammation and reproductive tract infections in a low risk pregnant population in Latvia. Acta Obstet Gynecol Scand. 2008;87(3):360-5.
  9. Vieira-Baptista P, Lima-Silva J, Pinto C, Saldanha C, Beires J, Martinez-de-Oliveira J, et al. Bacterial vaginosis, aerobic vaginitis, vaginal inflammation and major Pap smear abnormalities. Eur J Clin Microbiol Infect Dis. 2016;35(4):657-64.
  10. Martora F, Pinto F, Folliero V, Cammarota M, Dell’Annunziata F, Squillaci G, et al. Isolation, characterization and analysis of pro-inflammatory potential of Klebsiella pneumoniae outer membrane vesicles. Microb Pathog. 2019;136:103719.
  11. Kaambo E, Africa C, Chambuso R, Passmore J-AS. Vaginal microbiomes associated with aerobic vaginitis and bacterial vaginosis. Front Public health. 2018;6:78.
  12. Baron EJ. Specimen collection, transport, and processing: bacteriology. Manual Clin Microbiol. 2015:270-315.
  13. Tille P. Bailey & Scott's diagnostic microbiology-E-Book: Elsevier Health Sciences; 2015.
  14. Nu PAT, Nguyen VQH, Cao NT, Dessì D, Rappelli P, Fiori PL. Prevalence of Trichomonas vaginalis infection in symptomatic and asymptomatic women in Central Vietnam. J Infect Dev Ctries. 2015;9(06):655-60.
  15. Donders G, Bellen G, Rezeberga D. Aerobic vaginitis in pregnancy. BJOG. 2011;118(10):1163-70.
  16. Jabuk SIA. Prevalence of aerobic bacterial vaginosis among Intrauterine Contraceptive Device users women in Hilla city. J Babylon Univ. 2014:2424-31.
  17. Yasin J, Ayalew G, Dagnaw M, Shiferaw G, Mekonnen F. Vulvovaginitis Prevalence Among Women in Gondar, Northwest Ethiopia: Special Emphasis on Aerobic Vaginitis Causing Bacterial Profile, Antimicrobial Susceptibility Pattern, and Associated Factors. Infect Drug Resist. 2021;14:4567.
  18. Sangeetha K, Golia S, Vasudha C. A study of aerobic bacterial pathogens associated with vaginitis in reproductive age group women (15-45 years) and their sensitivity pattern. IJRMS. 2015.
  19. Serretiello E, Santella B, Folliero V, Iervolino D, Santoro E, Manente R, et al. Prevalence and Antibiotic Resistance Profile of Bacterial Pathogens in Aerobic Vaginitis: A Retrospective Study in Italy. Antibiotics. 2021;10(9):1133.
  20. Hayat IM, Nagat SS, Nermine N, Zeinab AB. Prevalence of vaginal infection and associated risk health behaviors among married women in Ismailia city. Int J Curr Microbiol Appl Sci. 2015;4(5):555-67.
  21. Kumar G, Singh K. Microbial Profile of High Vaginal Swab From Symptomatic Women of Reproductive Age Group: Data from Tertiary Care Hospital. Int J Sci Res. 2015;4(7):2672-73.
  22. Tang Y, Yu F, Hu Z, Peng L, Jiang Y. Characterization of aerobic vaginitis in late pregnancy in a Chinese population: A STROBE-compliant study. Medicine. 2020;99(25).
  23. Krishnasamy L, Saikumar C, Kumaramanickavel G. Aerobic bacterial pathogens causing vaginitis in patients attending a tertiary care hospital and their antibiotic susceptibility pattern. J Pure Appl Microbiol. 2019;13(2):1169-74.
  24. Mulu W, Yimer M, Zenebe Y, Abera B. Common causes of vaginal infections and antibiotic susceptibility of aerobic bacterial isolates in women of reproductive age attending at Felegehiwot referral Hospital, Ethiopia: a cross sectional study. BMC Women's Health. 2015;15(1):1-9.
  25. Wójkowska-Mach J, Pomorska-Wesołowska M, Romanik M, Romaniszyn D. Prevalence and antimicrobial susceptibility profiles of microorganisms associated with lower reproductive tract infections in women from southern poland—Retrospective laboratory-based study. Int J Environ Res Public Health. 2021;18(1):335.
  26. Shaikh S, Waghmare P, Sharma A, Ingole K, Bawane R. A Retrospective Evaluation of Vaginitis in Women of Reproductive Age Group in a Tertiary Care Hospital in Solapur, India. Int J Curr Microbiol App Sci. 2018;7(02):762-8.
  27. Organization WH. Sexually transmitted and other reproductive tract infections: a guide to essential practice: World Health Organization; 2005.
  28. Strus M, Pilarczyk-Żurek M, Adamski P, Janeczko J, Heczko PB, Tomusiak A. Bacterial infections of the lower genital tract in fertile and infertile women from the southeastern Poland. Ginekol Pol. 2013;84(5).
  29. Magiorakos A-P, Srinivasan A, Carey RB, Carmeli Y, Falagas M, Giske C, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. 2012;18(3):268-81.
  1. Chakraborty A, Pal NK, Sarkar S, Gupta MS. Antibiotic resistance pattern of Enterococci isolates from nosocomial infections in a tertiary care hospital in Eastern India. J Nat Sci Biol Med. 2015;6(2):394.
آمار
تعداد مشاهده مقاله: 3,496
تعداد دریافت فایل اصل مقاله: 6,525


counter
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب