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Abdulla, A. A, Abdulaali Abed, T, Fadhel Abbas Awadh, E. (1401). Hematological Parameters in COVID-19 Patients: Association with Severity of the Disease. سامانه مدیریت نشریات علمی, 77(6), 2415-2421. doi: 10.22092/ari.2022.358363.2208
A. A Abdulla; T Abdulaali Abed; E Fadhel Abbas Awadh. "Hematological Parameters in COVID-19 Patients: Association with Severity of the Disease". سامانه مدیریت نشریات علمی, 77, 6, 1401, 2415-2421. doi: 10.22092/ari.2022.358363.2208
Abdulla, A. A, Abdulaali Abed, T, Fadhel Abbas Awadh, E. (1401). 'Hematological Parameters in COVID-19 Patients: Association with Severity of the Disease', سامانه مدیریت نشریات علمی, 77(6), pp. 2415-2421. doi: 10.22092/ari.2022.358363.2208
Abdulla, A. A, Abdulaali Abed, T, Fadhel Abbas Awadh, E. Hematological Parameters in COVID-19 Patients: Association with Severity of the Disease. سامانه مدیریت نشریات علمی, 1401; 77(6): 2415-2421. doi: 10.22092/ari.2022.358363.2208

Hematological Parameters in COVID-19 Patients: Association with Severity of the Disease

Archives of Razi Institute
مقاله 49، دوره 77، شماره 6، بهمن و اسفند 2022، صفحه 2415-2421    اصل مقاله (606.47 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.358363.2208
نویسندگان
A. A Abdulla* ؛ T Abdulaali Abed؛ E Fadhel Abbas Awadh
Department of Biology, College of Sciences, University of Babylon, Babylon, Iraq
چکیده
The novel coronavirus (COVID-19) produced severe acute respiratory coronavirus syndrome (SARS-CoV-2; formerly known as 2019-nCoV) and has mild to fatal symptoms. This study aimed to investigate the different blood markers in confirmed positive COVID-19 individuals and see how they associated with the severity of the condition. A cross-sectional study was conducted from September 2020 to March 2021 on seventy-six (20 female and 56 male) Iraqi patients unvaccinated against COVID-19. The mean age of the study subjects was (47.00±13.31; 43.86±14.27) for males and females, respectively. 68.42% of the cases with mild illness, 14.47% with moderate illness, and 17.10% were severely ill. The severity of COVID-19 was assessed by several hematological parameters, including white blood cell (WBC) count, derived indicators such as neutrophils to lymphocyte ratio (NLR) and IL6, C-reactive protein (CRP), D-dimer, and S-ferritin. The results showed that lymphocyte count was lower in severely ill patients compared to patients with mild and moderate symptoms, with a significant difference between the three groups (2.274.83). Additionally, the NLR results showed a significant rise (11.56±1.23) in severe COVID-19. The results of the present study indicated that serum levels of IL6, CRP, and S-ferritin revealed significant differences (41.20±6.23 pg/ml), (50.66±12.55 mg/l), and (454.60±95.69 ng/ml) at (P≤0.05) in sever ill compared with mild and moderately ill patients respectively. The results indicated a highly significant positive correlation between IL6 and severity of COVID-19 infection at P<0.01. Furthermore, a positive connection is seen in Neutrophil, CRP, and NLR (0.229, 0.264, and 0.277) at (P≤0.05) respectively.
کلیدواژه‌ها
COVID-19؛ Disease Severity؛ Hematological Parameters؛ IL6؛ CRP
سایر فایل های مرتبط با مقاله
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