اخبار و اعلانات

 آمار

تعداد نشریات284
تعداد نشریات سازمان82
تعداد شماره‌ها3,049
تعداد مقالات34,082
تعداد مشاهده مقاله46,513,590
تعداد دریافت فایل اصل مقاله77,565,174
Obaid Khazaal, M, Çanlı, M, Abdul Kareem Jabbar, E. (1401). Molecular and Physiological Study in Patients with Coronavirus in Thi-Qar Province Iraq. سامانه مدیریت نشریات علمی, 77(5), 2001-2006. doi: 10.22092/ari.2022.358337.2199
M Obaid Khazaal; M Çanlı; E Abdul Kareem Jabbar. "Molecular and Physiological Study in Patients with Coronavirus in Thi-Qar Province Iraq". سامانه مدیریت نشریات علمی, 77, 5, 1401, 2001-2006. doi: 10.22092/ari.2022.358337.2199
Obaid Khazaal, M, Çanlı, M, Abdul Kareem Jabbar, E. (1401). 'Molecular and Physiological Study in Patients with Coronavirus in Thi-Qar Province Iraq', سامانه مدیریت نشریات علمی, 77(5), pp. 2001-2006. doi: 10.22092/ari.2022.358337.2199
Obaid Khazaal, M, Çanlı, M, Abdul Kareem Jabbar, E. Molecular and Physiological Study in Patients with Coronavirus in Thi-Qar Province Iraq. سامانه مدیریت نشریات علمی, 1401; 77(5): 2001-2006. doi: 10.22092/ari.2022.358337.2199

Molecular and Physiological Study in Patients with Coronavirus in Thi-Qar Province Iraq

Archives of Razi Institute
مقاله 61، دوره 77، شماره 5، آذر و دی 2022، صفحه 2001-2006    اصل مقاله (582.75 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.358337.2199
نویسندگان
M Obaid Khazaal* 1؛ M Çanlı2؛ E Abdul Kareem Jabbar3
1Ahi Evran University, Kırşehir, Turkey
2Chemistry and Chemical Processing Technologies Department, Mucur Vocational School, Kırşehir Ahi Evran University, Kırşehir, Turkey
3College of Nursing, University of Thi Qar, Nasiriyah, Iraq
چکیده
The current study aimed to study the effect of Covid-19 disease on some physiological parameters for assessing the physiological effect of Covid-19. The current study included 100 patients, 50 males, and 50 females, whose ages ranged from 10 – 73 years infected with Covid-19 molecularly diagnosed at AL-Imam Hussein Teaching Hospital in Thi-Qar Province from April to August 2021 and 50 people as a control group. The results illustrated a significant decrease in the level of hemoglobin, lymphocyte, and platelet in the patient's group, whereas a significant increase in the count of total white blood cells (WBC) was recorded in patients compared with the control group. The results showed that the hemoglobin level, WBC, and platelet increased significantly in males compared to females, while the lymphocytes increased significantly in female patients. The results of age groups showed non-significant differences in the hematological parameters. The current results illustrated a significant increase in the level of blood urea, serum creatinine, and random blood sugar in the patient's group. According to the gender of patients, the blood urea increased significantly in the female group, while the blood sugar increased significantly in the male group. On the other hand, the serum creatinine had no significant difference. According to age groups, a significant increase in blood urea was recorded in patients over 70 years, but no differences in both creatinine and random blood sugar level were noted. The current study recorded that the concentration of CRP, ferritin, and D. Dimer was significantly higher in patients; according to gender, the level of CRP and ferritin increased non-significantly compared with a male group of patients, while D. Dimer increased significantly in the female group. According to age group, only CRP increased significantly in the first age group compared with other age groups. The sequencing analysis was performed for 10 isolated Covid-19, and the result indicates that only one isolated sample has a sequencing identity of 99,5% with Covid-19 in Iran.
کلیدواژه‌ها
Covid-19؛ Hematological؛ spike protein؛ Angiotensin 2؛ ACE2
مراجع
  1. Bogoch II, Watts A, Thomas-Bachli A, Huber C, Kraemer MU, Khan K. Pneumonia of unknown aetiology in Wuhan, China: potential for international spread via commercial air travel. J Travel Med. 2020;27(2):taaa008.
  2. Decaro N. Alphacoronavirus‡: Coronaviridae. The Springer Index of Viruses. 2011:371.
  3. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506.
  4. Zhou P, Yang X-L, Wang X-G, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579(7798):270-3.
  5. Zhou G, Chen S, Chen Z. Back to the spring of 2020: facts and hope of COVID-19 outbreak. Springer; 2020. p. 113-6.
  6. Forni D, Cagliani R, Clerici M, Sironi M. Molecular evolution of human coronavirus genomes. Trends Microbiol. 2017;25(1):35-48.
  7. Asghar MS, Khan NA, Haider Kazmi SJ, Ahmed A, Hassan M, Jawed R, et al. Hematological parameters predicting severity and mortality in COVID-19 patients of Pakistan: a retrospective comparative analysis. J Community Hosp Intern Med. 2020;10(6):514-20.
  8. Usul E, Şan İ, Bekgöz B, Şahin A. Role of hematological parameters in COVID-19 patients in the emergency room. Biomark Med. 2020;14(13):1207-15.
  9. Anurag A, Jha PK, Kumar A. Differential white blood cell count in the COVID-19: A cross-sectional study of 148 patients. Diabetes Metab Syndr. 2020;14(6):2099-102.
  10. Lagunas‐Rangel FA. Neutrophil‐to‐lymphocyte ratio and lymphocyte‐to‐C‐reactive protein ratio in patients with severe coronavirus disease 2019 (COVID‐19): a meta‐analysis. J Med Virol. 2020.
  11. Peñaloza HF, Lee JS, Ray P. Neutrophils and lymphopenia, an unknown axis in severe COVID-19 disease. PLoS Pathog. 2021;17(9):e1009850.
  12. Aktar S, Ahamad M, Rashed-Al-Mahfuz M, Azad A, Uddin S, Kamal A, et al. Predicting patient COVID-19 disease severity by means of statistical and machine learning analysis of blood cell transcriptome data. arXiv. 2020.
  13. Qu R, Ling Y, Zhang Yhz, Wei Ly, Chen X, Li Xm, et al. Platelet‐to‐lymphocyte ratio is associated with prognosis in patients with coronavirus disease‐19. J Med Virol. 2020;92(9):1533-41.
  1. Ok F, Erdogan O, Durmus E, Carkci S, Canik A. Predictive values of blood urea nitrogen/creatinine ratio and other routine blood parameters on disease severity and survival of COVID‐19 patients. J Med Virol. 2021;93(2):786-93.
  2. Cheng Y, Luo R, Wang K, Zhang M, Wang Z, Dong L, et al. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Int. 2020;97(5):829-38.
  3. Chu KH, Tsang WK, Tang CS, Lam MF, Lai FM, To KF, et al. Acute renal impairment in coronavirus-associated severe acute respiratory syndrome. Kidney Int. 2005;67(2):698-705.
  4. Ge YL, Liu CH, Wang N, Xu J, Zhu XY, Su CS, et al. Elevated Plasma D-Dimer in Adult Community-Acquired Pneumonia Patients is Associated with an Increased Inflammatory Reaction and Lower Survival. Clin Lab. 2019;65(1).
  5. Qiu H, Wu J, Hong L, Luo Y, Song Q, Chen D. Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study. Lancet Infect Dis. 2020;20(6):689-96.
  6. Jiang F, Deng L, Zhang L, Cai Y, Cheung CW, Xia Z. Review of the clinical characteristics of coronavirus disease 2019 (COVID-19). J Gen Intern Med. 2020;35(5):1545-9.
  7. Li Z, Wu M, Yao J, Guo J, Liao X, Song S, et al. Caution on kidney dysfunctions of COVID-19 patients. MedRxiv. 2020.
  8. Bhandari S, Shaktawat AS, Tak A, Patel B, Shukla J, Singhal S, et al. Logistic regression analysis to predict mortality risk in COVID-19 patients from routine hematologic parameters. Ibnosina J Med Bio Sci. 2020;12(2):123.
  9. Singh AK, Gupta R, Ghosh A, Misra A. Diabetes in COVID-19: Prevalence, pathophysiology, prognosis and practical considerations. Diabetes Metab Syndr. 2020;14(4):303-10.
آمار
تعداد مشاهده مقاله: 1,338
تعداد دریافت فایل اصل مقاله: 2,399


counter
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب