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Dehghani, Mostafa, Hashemzadeh, Pejman, Cheraghi, Mostafa, Nazari, Afshin, Sedighi, Mehrnoosh. (1402). Effects of Medicinal Plants and Secondary Metabolites on the Most Important Risk Factors of Cardiovascular Diseases: A Review. سامانه مدیریت نشریات علمی, 12(4), 481-493. doi: 10.22092/jmpb.2022.355944.1397
Mostafa Dehghani; Pejman Hashemzadeh; Mostafa Cheraghi; Afshin Nazari; Mehrnoosh Sedighi. "Effects of Medicinal Plants and Secondary Metabolites on the Most Important Risk Factors of Cardiovascular Diseases: A Review". سامانه مدیریت نشریات علمی, 12, 4, 1402, 481-493. doi: 10.22092/jmpb.2022.355944.1397
Dehghani, Mostafa, Hashemzadeh, Pejman, Cheraghi, Mostafa, Nazari, Afshin, Sedighi, Mehrnoosh. (1402). 'Effects of Medicinal Plants and Secondary Metabolites on the Most Important Risk Factors of Cardiovascular Diseases: A Review', سامانه مدیریت نشریات علمی, 12(4), pp. 481-493. doi: 10.22092/jmpb.2022.355944.1397
Dehghani, Mostafa, Hashemzadeh, Pejman, Cheraghi, Mostafa, Nazari, Afshin, Sedighi, Mehrnoosh. Effects of Medicinal Plants and Secondary Metabolites on the Most Important Risk Factors of Cardiovascular Diseases: A Review. سامانه مدیریت نشریات علمی, 1402; 12(4): 481-493. doi: 10.22092/jmpb.2022.355944.1397

Effects of Medicinal Plants and Secondary Metabolites on the Most Important Risk Factors of Cardiovascular Diseases: A Review

Journal of Medicinal plants and By-products
مقاله 19، دوره 12، شماره 4، اسفند 2023، صفحه 481-493    اصل مقاله (782.78 K)
نوع مقاله: Research Paper
شناسه دیجیتال (DOI): 10.22092/jmpb.2022.355944.1397
نویسندگان
Mostafa Dehghani1؛ Pejman Hashemzadeh2؛ Mostafa Cheraghi1؛ Afshin Nazari1؛ Mehrnoosh Sedighi* 1
1Cardiovascular Research Center, Shahid Rahimi Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran
2Department of Medical Biotechnology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
چکیده
Although the people’s knowledge about cardiovascular diseases (CVDs) has increased, these diseases are still among the main causes of mortality in industrialized and developing countries and communities. For controlling and treating CVDs, both pharmaceutical and non- pharmaceutical methods can be helpful. The high global prevalence of CVDs and associated serious effects on the body organs made them a major health problem in all societies. Concerns about the side effects of synthetic drugs lead to their improper usage and rejection by patients and subsequently a disrupted disease management process. For this reason, today, a new approach is emerging toward medicinal plants, and in fact, they are subjected to extensive research these days. The aim of this review was to introduce medicinal plants and present their action mechanisms, which have been effective in the treatment of CVDs. A literature search was conducted to recruit the articles published in various databases. We also reviewed reference textbooks to elaborate on the mechanisms of action of various plants in the treatment of cardiac diseases and investigate the involved molecular mediators and pathways. Studies have shown that herbal medicines through various mechanisms such as lowering blood pressure, resolving diabetes, improving atherosclerosis, reducing blood fats, inducing nitric oxide, blocking calcium channels, and suppressing the renin-angiotensin pathway can help improve CVDs.
کلیدواژه‌ها
Heart diseases؛ Antioxidants؛ Herbal medicines
مراجع
  1. Chen S., et al. Roles and potential clinical implications of tissue transglutaminase in cardiovascular diseases. Pharmacological Res. 2022; p. 106085.
  2. Cox F.F., et al. Protective Effects of Curcumin in Cardiovascular Diseases—Impact on Oxidative Stress and Mitochondria. Cells. 2022; 11(3): p. 342.
  3. Kearney P.M., et al. Worldwide prevalence of hypertension: a systematic review. J hypertension. 2004; 22(1): p. 11-19.
  4. Zhao D. Epidemiological features of cardiovascular disease in Asia. JACC: Asia. 2021; 1(1): p. 1-13.
  5. Chockalingam A., Campbell N.R., Fodor J.G. Worldwide epidemic of hypertension. Canadian J cardiology. 2006; 22(7): p. 553-555.
  6. Mittal B.V. Singh A.K. Hypertension in the developing world: challenges and opportunities. American J Kidney Diseases. 2010; 55(3): p. 590-598.
  7. Association A.D., Standards of medical care in diabetes. Abridged for primary care providers. Clinical diabetes: a publication of the American Diabetes Association. 2016; 34(1): p. 3.
  8. Ghalavand A., et al. The effect of resistance training on cardio-metabolic factors in males with type 2 diabetes. Jundishapur J Chronic Disease Care. 2014; 3(4): p. e23346.
  9. Mirfeizi M., et al. Effects of cinnamon on controlling blood glucose and lipids in patients with type II diabetes mellitus: A double blind, randomized clinical trial. medical J mashhad university of medical sciences. 2014; 57(3): p. 533-541.
  10. Katzung B.G., Basic and clinical pharmacology. 2012: Mc Graw Hill.
  11. Mombouli J.-V. and P.M. Vanhoutte, Endothelial dysfunction: from physiology to therapy. J Molecular and cellular cardiology. 1999; 31(1): p. 61-74.
  12. Hoerger T.J., et al. Treatment patterns and distribution of low-density lipoprotein cholesterol levels in treatment-eligible United States adults. The American J Cardiology. 1998; 82(1): p. 61-65.
  13. Manninen V., et al. Lipid alterations and decline in the incidence of coronary heart disease in the Helsinki Heart Study. Jama. 1988; 260(5): p. 641-651.
  14. Catapano A.L., Pirillo A., Norata G.D. Vascular inflammation and low‐density lipoproteins: is cholesterol the link? A lesson from the clinical trials. British J pharmacology. 2017; 174(22): p. 3973-3985.
  15. Rai D., et al. Role of aqueous extract of Cynodon dactylon in prevention of carbofuran-induced oxidative stress and acetylcholinesterase inhibition in rat brain. Cellular and Molecular Biology. 2011; 57(1): p. 135-142.
  16. Trevor A.J., et al. Pharmacology examination & board review. 2010; McGraw-Hill Medical New York.
  17. Evangelista S., Maggi C., Meli A. The role of the local anaesthetic properties of beta-adrenoceptor blocking agents in antagonizing CaCl2-induced arrhythmias in the rat. British J Pharmacology. 1981; 73(3): p. 725.
  18. Kearney P.M., et al. Global burden of hypertension: analysis of worldwide data. The lancet. 2005; 365(9455): p. 217-223.
  19. Benner J.S., et al. Estimated prevalence of uncontrolled hypertension and multiple cardiovascular risk factors and their associated risk of coronary heart disease in the United States. J the American Society of Hypertension. 2008;2(1): p. 44-53.
  20. Zanchetti A., et al. Different effects of antihypertensive regimens based on fosinopril or hydrochlorothiazide with or without lipid lowering by pravastatin on progression of asymptomatic carotid atherosclerosis: principal results of PHYLLIS—a randomized double-blind trial. Stroke. 2004; 35(12): p. 2807-2812.
  21. Barrios V., Escobar C., Importance of blood pressure control in hypertensive patients with coronary heart disease in clinical practice to reduce the risk of stroke. Stroke. 2009; 40(6): p. e469-e469.
  22. Bent S. Herbal medicine in the United States: review of efficacy, safety, and regulation. J general internal medicine. 2008; 23(6): p. 854-859.
  23. Barrett B., Kiefer D., Rabago D. Assessing the risks and benefits of herbal medicine: an overview of scientific evidence. Alternative Therapies in Health and Medicine. 1999; 5(4): p. 40.
  24. Bhardwaj P., et al. Control of hyperglycaemia and hyperlipidaemia by plant product. The J the Association of Physicians of India. 1994; 42(1): p. 33-35.
  25. Böhm H., et al. Flavonols, flavone and anthocyanins as natural antioxidants of food and their possible role in the prevention of chronic diseases. Zeitschrift fur Ernahrungswissenschaft. 1998; 37(2): p. 147-163.
  26. Hou L., et al. Inhibition of human low density lipoprotein oxidation by flavonols and their glycosides. Chemistry and Physics of Lipids. 2004; 129(2): p. 209-219.
  27. Mennen L.I., et al. Consumption of foods rich in flavonoids is related to a decreased cardiovascular risk in apparently healthy French women. The J Nutrition. 2004; 134(4): p. 923-926.
  28. Chrysohoou C., et al. The emerging anti-inflammatory role of HDL-cholesterol, illustrated in cardiovascular disease free population; the ATTICA study. Int J Cardiology. 2007; 122(1): p. 29-33.
  29. Chandra M. Effect of vitamin E on the platelet xanthine oxldase and lipid per-oxidation in the patients of myocardial infarction. J Clinical Biochemistry. 2008; 21: p. 26-29.
  30. Xia Y., Khatchikian G., Zweier J.L. Adenosine deaminase inhibition prevents free radical-mediated injury in the postischemic heart. J Biological Chem. 1996; 271(17): p. 10096-10102.
  31. Patil N., Chavan V., Karnik N. Antioxidant status in patients with acute myocardial infarction. Indian J Clinical Biochemistry. 2007; 22(1): p. 45-51.
  32. Farzami B., et al. Induction of insulin secretion by a component of Urtica dioica leave extract in perifused Islets of Langerhans and its in vivo effects in normal and streptozotocin diabetic rats. J Ethnopharmacology. 2003; 89(1): p. 47-53.
  33. Tarighat E.A., Namazi N., Bahrami A. Effect of hydro-alcoholic nettle extract on lipid profiles and blood pressure in type 2 diabetes patients. Iranian J Endocrinology and Metabolism. 2012; 13(5): p. 450-459.
  34. Dizaye K., Alberzingi B., Sulaiman S. Renal and vascular studies of aqueous extract of Urtica dioica in rats and rabbits. Iraqi J Veterinary Sciences. 2013; 27(1): p. 25-31.
  35. Tahri A., et al. Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat. J Ethnopharmacology, 2000; 73(1-2): p. 95-100.
  36. Järvisalo M.J., et al. Carotid artery intima-media thickness in children with type 1 diabetes. Diabetes. 2002; 51(2): p. 493-498.
  37. Almario R.U., et al. Effects of walnut consumption on plasma fatty acids and lipoproteins in combined hyperlipidemia. The American J Cclinical Nutrition. 2001; 74(1): p. 72-79.
  38. Han Y.-F., et al. Isolation and characterisation of the sesquiterpene lactones from Lactuca sativa L var. anagustata. Food Chem. 2010; 120(4): p. 1083-1088.
  39. Mulabagal V., et al. In vitro evaluation of red and green lettuce (Lactuca sativa) for functional food properties. Food Chem. 2010; 118(2): p. 300-306.
  40. Gawlik-Dziki, U., Złotek U., Świeca M. Characterization of polyphenol oxidase from butter lettuce (Lactuca sativa var. capitata L.). Food Chem. 2008; 107(1): p. 129-135.
  41. Manning B.M., et al. Carbon-fiber microelectrode amperometry reveals sickle-cell-induced inflammation and chronic morphine effects on single mast cells. ACS chemical biology. 2012; 7(3): p. 543-551.
  42. Wypasek E., et al. Morphine-modulated mast cell migration and proliferation during early stages of zymosan-induced peritonitis in CBA mice. Folia biologica. 2011; 59(3-4): p. 99-106.
  43. Guedes A., et al. Comparison of plasma histamine levels after intravenous administration of hydromorphone and morphine in dogs. J veterinary pharmacology and therapeutics. 2007; 30(6): p. 516-522.
  44. Shanazari A.A.P., et al. Acute and chronic effects of morphine on cardiovascular system and the baroreflexes sensitivity during severe increase in blood pressure in rats. ARYA atherosclerosis. 2011; 7(3): p. 111.
  45. Ng C.J., et al. The paraoxonase gene family and atherosclerosis. Free Radical Biology and Medicine. 2005; 38(2): p. 153-163.
  46. José Bagur M., et al. Saffron: An old medicinal plant and a potential novel functional food. Molecules. 2018; 23(1): p. 30.
  47. Alavizadeh S.H., Hosseinzadeh H. Bioactivity assessment and toxicity of crocin: a comprehensive review. Food and Chemical Toxicology. 2014; 64: p. 65-80.
  48. Fatehi M., Rashidabady T., Fatehi-Hassanabad Z. Effects of Crocus sativus petals’ extract on rat blood pressure and on responses induced by electrical field stimulation in the rat isolated vas deferens and guinea-pig ileum. J ethnopharmacology. 2003; 84(2-3): p. 199-203.
  49. Mancini A., et al. Crocetin, a carotenoid derived from saffron (Crocus sativus L.), improves acetylcholine-induced vascular relaxation in hypertension. J vascular research. 2014; 51(5): p. 393-404.
  50. He S.-Y., Qian Z.-Y., Tang F.-T., Effect of crocin on intracellular calcium concentration in cultured bovine aortic smooth muscle cells. 藥學學報. 2004; 39(10): p. 778-781.
  51. Boskabady M., et al. Effect of aqueous‐ethanol extract from Crocus sativus (saffron) on guinea‐pig isolated heart. Phytotherapy Research: An International J Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives. 2008; 22(3): p. 330-334.
  52. Kander M.C., Cui Y., Liu Z. Gender difference in oxidative stress: a new look at the mechanisms for cardiovascular diseases. J cellular and molecular medicine. 2017; 21(5): p. 1024-1032.
  53. Zheng Y.-Q., et al. Effects of crocin on reperfusion-induced oxidative/nitrative injury to cerebral microvessels after global cerebral ischemia. Brain Res. 2007; 1138: p. 86-94.
  54. Wang, Y., et al. Crocin attenuates oxidative stress and myocardial infarction injury in rats. International heart J. 2018; p. 17-114.
  55. Hosseini A., Razavi B.M., Hosseinzadeh H. Pharmacokinetic properties of saffron and its active components. European J Drug Metabolism and Pharmacokinetics. 2018; 43(4): p. 383-390.
  56. Xi L., Qian Z. Pharmacological properties of crocetin and crocin (digentiobiosyl ester of crocetin) from saffron. Natural Product Communications. 2006; 1(1): p. 1934578X0600100112.
  57. Bhatt P., et al. Chemical composition and nutraceutical potential of Indian borage (Plectranthus amboinicus) stem extract. J Chem. 2013; 2013.
  58. Siciliano T., et al. Pyrrolizidine alkaloids from Anchusa strigosa and their antifeedant activity. Phytochemistry. 2005; 66(13): p. 1593-1600.
  59. Ranjbar A., et al. Antioxidant activity of Iranian Echium amoenum Fisch & CA Mey flower decoction in humans: a cross-sectional before/after clinical trial. Evidence-Based Complementary and Alternative Medicine. 2006; 3.
  60. Horrobin D. Nutritional and medical importance of gamma-linolenic acid. Progress in lipid research. 1992; 31(2): p. 163-194.
  61. Engler M., Engler M. Dietary borage oil alters plasma, hepatic and vascular tissue fatty acid composition in spontaneously hypertensive rats. Prostaglandins, leukotrienes and essential fatty acids. 1998; 59(1): p. 11-15.
  62. Asadi-Samani M., Bahmani M., Rafieian-Kopaei M. The chemical composition, botanical characteristic and biological activities of Borago officinalis: a review. Asian Pacific J tropical medicine. 2014; 7: p. S22-S28.
  63. Abed A., et al. Effect of Echium amoenum Fisch. et Mey a traditional Iranian herbal remedy in an experimental model of acute pancreatitis. ISRN gastroenterology. 2012; 2012.
  64. Razavi S.M., et al. Bioactivity of Malva sylvestris L., a medicinal plant from Iran. Iranian J basic medical sciences. 2011; 14(6): p. 574.
  65. Mustafa A., Ali M. New steroidal lactones and homomonoterpenic glucoside from fruits of Malva sylvestris L. L. Acta Pol Pharm, 2011; 68(3): p. 393-401.
  66. Eloff J. Which extractant should be used for the screening and isolation of antimicrobial components from plants? J ethnopharmacology. 1998; 60(1): p. 1-8.
  67. Santhi R., Kalaiselvi K., Annapoorani S. ANTI-LIPID PEROXIDATIVE ACTIVITIES OF Cynodon dactylon AND Moringa oleifera AGAINST ELA INDUCED MICE. 2009.
  68. Golshan A., et al. Kidney stone formation and antioxidant effects of Cynodon dactylon decoction in male Wistar rats. Avicenna J phytomedicine. 2017; 7(2): p. 180.
  69. Abtahi Froushani, S. Effect of hydroalcholic extract of Cynodon dactylon the phagocytosis and respiratory burst of peritoneal macrophages of NMRI mice. Armaghane danesh, 2016; 20(11): p. 985-995.
  70. Ridker P.M. From C-reactive protein to interleukin-6 to interleukin-1: moving upstream to identify novel targets for atheroprotection. Circulation research. 2016; 118(1): p. 145-156.
  71. Mosadegh M., et al. The study of phytochemical, antifungal and antibacterial effects of Teucrium polium and Cichourium intybus. 2002.
  72. Bedir E., et al. Neo-clerodane diterpenoids from Teucrium polium. Phytochemistry. 1999; 51(7): p. 921-925.
  73. Rasekh H., Khoshnood-Mansourkhani M., Kamalinejad M. Hypolipidemic effects of Teucrium polium in rats. Fitoterapia. 2001; 72(8): p. 937-939.
  74. Parsaee H., Shafiee-Nick R. Anti-spasmodic and anti-nociceptive effects of Teucrium polium aqueous extract. Iranian Biomedical J. 2006; 10(3): p. 145-149.
  75. GHARIB N.M.K., OMIDI B.F., Vakilzadeh G. Spasmolytic effect of Teucrium polium on virgin rat uterus. 2005.
  76. Suleiman M.-S., et al. Effect of Teucrium polium boiled leaf extract on intestinal motility and blood pressure. J Ethnopharmacology. 1988; 22(1): p. 111-116.
  77. Rigelsky, J.M. Sweet B.V. Hawthorn: pharmacology and therapeutic uses. American J Health-System Pharmacy. 2002; 59(5): p. 417-422.
  78. Cui T., et al. Polyphenolic content and physiological activities of Chinese hawthorn extracts. Bioscience, Biotechnology, and Biochemistry. 2006; 70(12): p. 2948-2956.
  79. Zhang Z., et al. Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet. The J nutrition. 2002; 132(1): p. 5-10.
  80. Khori V., et al. Frequency-dependent anti arrhythmic effects of crataegus monogyna on the extracellular field potential recordings in the rabbit atrioventricular node, an experimental model of AF. Physiology and Pharmacology. 2011; 15(1): p. 36-46.
  81. Schüssler M., Hölzl J., Fricke U. Myocardial effects of flavonoids from Crataegus species. Arzneimittel-Forschung. 1995; 45(8): p. 842.
  82. Tadić V.M., et al. Anti-inflammatory, gastroprotective, free-radical-scavenging, and antimicrobial activities of hawthorn berries ethanol extract. J Agric and Food Chem. 2008; 56(17): p. 7700-7709.
  83. Sahreen S., Khan M.R., Khan R.A. Hepatoprotective effects of methanol extract of Carissa opaca leaves on CCl 4-induced damage in rat. BMC complementary and alternative medicine. 2011; 11(1): p. 48.
  84. Williams C.A., et al. The flavonoids of Tanacetum parthenium and T. vulgare and their anti-inflammatory properties. Phytochemistry. 1999; 51(3): p. 417-423.
  85. Marimuthu S., et al. Protective role of ferulic acid on carbon tetrachloride-induced hyperlipidemia and histological alterations in experimental rats. J basic and clinical physiology and pharmacology. 2013; 24(1): p. 59-66.
  86. Javidnia K., et al. Chemical composition of Ferula persica Wild. essential oil from Iran. Flavour and fragrance J. 2005; 20(6): p. 605-606.
  87. Imenshahidi M., Hosseinzadeh H., Javadpour Y. Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats. Phytotherapy Research. 2010; 24(7): p. 990-994.
  88. Balasuriya B.N., Rupasinghe H.V. Plant flavonoids as angiotensin converting enzyme inhibitors in regulation of hypertension. Functional foods in health and disease. 2011; 1(5): p. 172-188.
  89. Shahverdi A.-R., et al. Bioassay-guided isolation and identification of an antibacterial compound from Ferula persica var. persica roots. 2005.
  90. Pawlowska A.M., et al. Flavonoids of Zizyphus jujuba L. and Zizyphus spina-christi (L.) Willd (Rhamnaceae) fruits. Food Chem. 2009; 112(4): p. 858-862.
  91. Al-Reza S.M., Bajpai V.K., Kang S.C. Antioxidant and antilisterial effect of seed essential oil and organic extracts from Zizyphus jujuba. Food and Chem Toxicology. 2009; 47(9): p. 2374-2380.
  92. Li J.-W., et al. Nutritional composition of five cultivars of Chinese jujube. Food Chem. 2007; 103(2): p. 454-460.
  93. Afzalpour M.E., et al. Effect of Ziziphus jujuba Supplementation before One Session of Acute Resistance Exercise on the Serum Glutathione Peroxidase and Superoxide Dismutase Activity. The Horizon of Medical Sci. 2015; 21(2): p. 97-104.
  94. Taati M., et al. Protective effects of Ziziphus jujuba fruit extract against ethanol-induced hippocampal oxidative stress and spatial memory impairment in rats. J Medicinal Plants Res. 2011; 5(6): p. 915-921.
  95. Ebrahimi S., et al. Protective effect of zizphus vulgaris extract, on liver toxicity in laboratory rats. Armaghane danesh. 2011; 16(2): p. 172-180.
  96. Wang H., et al. Effects of catechin enriched green tea on body composition. Obesity. 2010; 18(4): p. 773-779.
  97. Nagao T., et al. A catechin‐rich beverage improves obesity and blood glucose control in patients with type 2 diabetes. Obesity. 2009; 17(2): p. 310-317.
  98. Persson I.A., et al. Effects of green tea, black tea and Rooibos tea on angiotensin-converting enzyme and nitric oxide in healthy volunteers. Public health nutrition. 2010; 13(5): p. 730-737.
  99. PAKNAHAD Z., et al., The effect of green tea on body fat, anthropometric indices and blood pressure among overweight and obese women. 2012.
  100. Rahman K., G.M. Lowe, Garlic and cardiovascular disease: a critical review. The J of nutrition. 2006; 136(3): p. 736S-740S.
  101. Khatua T.N., Adela R., Banerjee S.K. Garlic and cardioprotection: insights into the molecular mechanisms. Can J Physiol Pharmacol. 2013; 91(6): p. 448-58.
  102. Takahashi M., Role of the SDF-1/CXCR4 system in myocardial infarction. Circulation J. 2010; 74(3): p. 418-423.
  103. Dobaczewski M., et al. CCR5 signaling suppresses inflammation and reduces adverse remodeling of the infarcted heart, mediating recruitment of regulatory T cells. The American J pathology. 2010; 176(5): p. 2177-2187.
  104. Cochain C., et al. The chemokine decoy receptor D6 prevents excessive inflammation and adverse ventricular remodeling after myocardial infarction. Arteriosclerosis, thrombosis, and vascular biology. 2012; 32(9): p. 2206-2213.
  105. Yamaguchi J.-i., et al. Stromal cell–derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization. Circulation. 2003; 107(9): p. 1322-1328.
  106. Hertog M.G., et al. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. The lancet. 1993; 342(8878): p. 1007-1011.
  107. Najafi M., et al. Effects of total extract of Dracocephalum moldavica on ischemia/reperfusion induced arrhythmias and infarct size in the isolated rat heart. Iranian J Basic Medical Sci. 2009; 11(4): p. 229-235.
  108. Eidi A., et al. Hepatoprotective activity of cinnamon ethanolic extract against CCI4-induced liver injury in rats. Excli J. 2012;11: p. 495.
  109. Kim H.S., Kwack S.J., Lee B.M. Lipid peroxidation, antioxidant enzymes, and benzo [a] pyrene-quinones in the blood of rats treated with benzo [a] pyrene. Chemico-biological interactions. 2000; 127(2): p. 139-150.
  110. Dong D.L., et al. Acidification alters antiarrhythmic drug blockade of the ether‐a‐go‐go‐related gene (HERG) channels. Basic & clinical pharmacology & toxicology. 2004; 94(5): p. 209-212.
  111. Pinsky M.R., et al. Changes in electrocardiographic morphology reflect instantaneous changes in left ventricular volume and output in cardiac surgery patients. The American J cardiology. 1995; 76(10): p. 667-674.
  112. Leitinger N., Schulman I.G. Phenotypic polarization of macrophages in atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology. 2013; 33(6): p. 1120-1126.
  113. Cimmino G., et al. The complex puzzle underlying the pathophysiology of acute coronary syndromes: from molecular basis to clinical manifestations. Expert review of cardiovascular therapy. 2012; 10(12): p. 1533-1543.
  114. Corwin E.J., et al. Potential Impact and Study Considerations of Metabolomics in Cardiovascular Health and Disease. 2017.
  115. Rauch U., et al. Thrombus formation on atherosclerotic plaques: pathogenesis and clinical consequences. Annals of internal medicine. 2001; 134(3): p. 224-238.
  116. Pandey N., et al. Enzymatic oxidant and antioxidants of human blood platelets in unstable angina and myocardial infarction. International J cardiology. 2000; 76(1): p. 33-38.
  117. Haserück N., et al. The plaque lipid lysophosphatidic acid stimulates platelet activation and platelet-monocyte aggregate formation in whole blood: involvement of P2Y1 and P2Y12 receptors. Blood. 2004; 103(7): p. 2585-2592.
  118. Dwivedi V.K., et al. Effect of vitamin E on platelet enzymatic anti-oxidants in the patients of myocardial infarction. Indian J Clinical Biochemistry. 2005; 20(1): p. 21-25.
  119. Gutteridge, J., Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clinical Chem. 1995; 41(12): p. 1819-1828.
  120. Parmley W.W. Nonlipoprotein risk factors for coronary heart disease: evaluation and management. The American J medicine. 1997; 102(2): p. 7-14.
  121. Haidari M., et al. Apolipoprotein B as the best predictor of coronary artery disease in Iranian normolipidemic patients. Clinical Biochemistry. 2001; 34(2): p. 149-155.
  122. Klag M.J., et al. Serum cholesterol in young men and subsequent cardiovascular disease. New England J Medicine. 1993; 328(5): p. 313-318.
  123. Yousofvand N. Soltany A. Effects of hydroalcoholic extract of dill (Anethum graveolens) on the serum levels of blood lipids cholesterol, triglycerides, LDL and HDL in male NMRI mice. J Pharmaceut Chem Biol Sci. 2015; 3: p. 114-21.
  124. Thomson M.J., Frenneaux M.P., Kaski J. Antioxidant treatment for heart failure: friend or foe? QJM: An International J Med. 2009; 102(5): p. 305-310.
  125. Bashar T. Akhter N. Study on oxidative stress and antioxidant level in patients of acute myocardial infarction before and after regular treatment. Bangladesh Medical Res Council Bulletin. 2014; 40(2): p. 79-84.
  126. Husain K., et al. Inflammation, oxidative stress and renin angiotensin system in atherosclerosis. World J Biological Chem. 2015; 6(3): p. 209.
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