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Shakir Abed Almjalawi, B, Alhamed, T. A, Alhesnawi, A. Sh. M. (1401). Antibacterial Activity of Boswellia carterii Aqueous Extract and Its Effect on Phagocytosis in vitro. سامانه مدیریت نشریات علمی, 77(2), 545-552. doi: 10.22092/ari.2022.356956.1946
B Shakir Abed Almjalawi; T. A Alhamed; A. Sh. M Alhesnawi. "Antibacterial Activity of Boswellia carterii Aqueous Extract and Its Effect on Phagocytosis in vitro". سامانه مدیریت نشریات علمی, 77, 2, 1401, 545-552. doi: 10.22092/ari.2022.356956.1946
Shakir Abed Almjalawi, B, Alhamed, T. A, Alhesnawi, A. Sh. M. (1401). 'Antibacterial Activity of Boswellia carterii Aqueous Extract and Its Effect on Phagocytosis in vitro', سامانه مدیریت نشریات علمی, 77(2), pp. 545-552. doi: 10.22092/ari.2022.356956.1946
Shakir Abed Almjalawi, B, Alhamed, T. A, Alhesnawi, A. Sh. M. Antibacterial Activity of Boswellia carterii Aqueous Extract and Its Effect on Phagocytosis in vitro. سامانه مدیریت نشریات علمی, 1401; 77(2): 545-552. doi: 10.22092/ari.2022.356956.1946

Antibacterial Activity of Boswellia carterii Aqueous Extract and Its Effect on Phagocytosis in vitro

Archives of Razi Institute
مقاله 5، دوره 77، شماره 2، خرداد و تیر 2022، صفحه 545-552    اصل مقاله (398.76 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.356956.1946
نویسندگان
B Shakir Abed Almjalawi* 1؛ T. A Alhamed2؛ A. Sh. M Alhesnawi1
1General Directorate of Education in Karbala, Karbala, Iraq
2College of Nursing, University of Warith Al-anbiyaa, Karbala, Iraq
چکیده
Boswellia serrata has been traditionally used for the treatment of several inflammatory diseases, and bacterial resistance to antibiotics has recently increased the use of bioproducts. The present study aimed to assess the antibacterial effect and phagocytic ability of the aqueous extract of the Boswellia serrata in bacteria isolated in nosocomial infections. Boswellia carterii plant was collected and prepared from the aqueous extract in different concentrations. A total of 125 samples were collected from various clinical sources, including urine, sputum, wounds, otitis, and blood, from patients of both genders in different age groups. The results demonstrated that out of the 59 infected samples, urine samples had the highest infection (68%), followed by wounds, sputum, and otitis reported as (60%), (44%), and (40%), respectively. On the other hand, blood samples had the lowest percentage of infection (28%). Microscopic diagnostic results, biochemical tests, API Staph System, API 20E System, and Vitek 2 Compact pointed out that the highest infection rates were related to Staphylococcus aureus (32.20%), Pseudomonas aeruginosa (25.33%), and Escherichia coli (22.03%), while the lowest infection rate was detected in Klebsiella pneumonia (20.33%). The results indicated that aqueous extract of Boswellia carterii had an antibacterial activity for all bacterial isolates, 25 mg/ml of extract gave an inhibition zone of 10.8 mm,10.4 mm, 7mm, and 10mm for S. aureus, E. coli, P aeruginosa, and K. pneumonia, respectively, while 200 mg/ml of extract gave 24 mm, 22 mm, 18.4 mm, and 20 mm, respectively. The results pointed to a significant increase in the phagocytosis rate, with the phagocytosis of blood samples treated with Boswellia carterii extract (79.7%), as compared to control samples (57.75%).  As evidenced by the results of this study, the aqueous extract of the Boswellia carterii plant showed antibacterial effects and a positive impact on the phagocytic ratio; nonetheless, it is recommended that further studies be conducted to characterize the compounds of this herb.
کلیدواژه‌ها
Antibacterial activity؛ Aqueous extract؛ Boswellia carterii؛ in vitro؛ Phagocytosis
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مراجع
  1. Bufield T. Frankincense-A Brief catch-up. Cropwatch newsletter. 2009:1-3.
  2. Unger MF. The new Unger's Bible handbook: Moody Publishers; 2005.
  3. Hostanska K, Daum G, Saller R. Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro. Anticancer Res. 2002;22(5):2853-62.
  4. Liu J-J, Nilsson Å, Oredsson S, Badmaev V, Zhao W-Z, Duan R-D. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis. 2002;23(12):2087-93.
  5. Wagner H, Püls S, Barghouti T, Staudinger A, Melchart D. Olibanum–Ruxiang. Chromatographic Fingerprint Analysis of Herbal Medicines Volume V: Springer; 2017. p. 79-86.
  6. Hussain H, Al-Harrasi A, Csuk R, Shamraiz U, Green IR, Ahmed I, et al. Therapeutic potential of boswellic acids: a patent review (1990-2015). Expert Opin Ther Pat. 2017;27(1):81-90.
  7. Estrada AC, Syrovets T, Pitterle K, Lunov O, Büchele B, Schimana-Pfeifer J, et al. Tirucallic acids are novel pleckstrin homology domain-dependent Akt inhibitors inducing apoptosis in prostate cancer cells. Mol Pharmacol. 2010;77(3):378-87.
  8. Helal EG, Mostafa AM, Ashour FA, Kahwash AA. Effect of Boswellia carterii Birdw on carbohydrate metabolism in diabetic male albino rats. Egypt J Hosp Med. 2005;20(1):38-45.
  9. Kohoude MJ, Gbaguidi F, Agbani P, Ayedoun M-A, Cazaux S, Bouajila J. Chemical composition and biological activities of extracts and essential oil of Boswellia dalzielii leaves. Pharm Biol. 2017;55(1):33-42.
  10. Abdel-Tawab M, Werz O, Schubert-Zsilavecz M. Boswellia serrata. Clin Pharmacokinet. 2011;50(6):349-69.
  11. Bonjar S. Evaluation of antibacterial properties of some medicinal plants used in Iran. J Ethnopharmacol. 2004;94(2-3):301-5.
  12. Camarda L, Dayton T, Di Stefano V, Pitonzo R, Schillaci D. Chemical composition and antimicrobial activity of some oleogum resin essential oils from Boswellia spp.(Burseraceae). Ann Chim. 2007;97(9):837-44.
  13. Forbes BA, Sahm DF, Weissfeld AS. Diagnostic microbiology: Mosby St Louis; 2007.
  14. Mackie, Mc-Cartney. Practical medical microbiology 4th ed. New York, USA1995.
  15. YH H. Bacteriological and genetical Study on Staphylococcus aureus Isolated From wound infections: Tikrit university; 2008.
  16. Wolf P, Elsässer-Beile U. Pseudomonas exotoxin A: from virulence factor to anti-cancer agent. Int J Med Microbiol. 2009;299(3):161-76.
  17. Sawa T, Shimizu M, Moriyama K, Wiener-Kronish JP. Association between Pseudomonas aeruginosa type III secretion, antibiotic resistance, and clinical outcome: a review. Crit Care. 2014;18(6):1-12.
  18. Ferrara AM. Treatment of hospital-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus. Int J Antimicrob Agents. 2007;30(1):19-24.
  19. Fairlamb AH, Gow NA, Matthews KR, Waters AP. Drug resistance in eukaryotic microorganisms. Nat Microbiol. 2016;1(7):1-15.
  20. Aiello SE, Moses MA, Allen DG. The Merck veterinary manual: Merck & Company, Incorporated; 2016.
  21. Büchele B, Zugmaier W, Simmet T. Analysis of pentacyclic triterpenic acids from frankincense gum resins and related phytopharmaceuticals by high-performance liquid chromatography. Identification of lupeolic acid, a novel pentacyclic triterpene. J Chromatogr B. 2003;791(1-2):21-30.
  22. Mothana RA, Lindequist U. Antimicrobial activity of some medicinal plants of the island Soqotra. J Ethnopharmacol. 2005;96(1-2):177-81.
  23. Basar S. Phytochemical investigations on Boswellia species: Comparative studies on the essential oils, pyrolysates and boswellic acids of Boswellia carterii Birdw, Boswellia serrata Roxb, Boswellia frereana Birdw, Boswellia neglecta S. Moore and Boswellia rivae Engl. 2005.
  24. Mothana RA, Lindequist U. Antimicrobial activity of some medicinal plants of the island Soqotra. J Ethnopharmacol. 2005;96(1-2):177-81.
  25. Sarrou S, Malli E, Tsilipounidaki K, Florou Z, Medvecky M, Skoulakis A, et al. MLSB-Resistant Staphylococcus aureus in Central Greece: Rate of Resistance and Molecular Characterization. Microb Drug Resist. 2019;25(4):543-50.
  26. Mikhaeil BR, Maatooq GT, Badria FA, Amer MM. Chemistry and immunomodulatory activity of frankincense oil. Z Naturforsch C. 2003;58(3-4):230-8.
  1. Umezu T. Evaluation of central nervous system acting effects of plant-derived essential oils using ambulatory activity in mice. 2013.
  2. Abbas FA, Al-Massarany SM, Khan S, Al-Howiriny TA, Mossa JS, Abourashed EA. Phytochemical and biological studies on Saudi Commiphora opobalsamum L. Nat Prod Res. 2007;21(5):383-91.
  3. Hilsden RJ, Verhoef MJ, Rasmussen H, Porcino A, DeBruyn JC. Use of complementary and alternative medicine by patients with inflammatory bowel disease. Inflamm Bowel Dis. 2011;17(2):655-62.
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