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Vahdat, Seyed Mohammad, Khavarpour, Maryam, Kazemi, Sohrab. (1398). Chemical Composition, Antimicrobial and Analgesic Properties of Rosmarinus officinalis L. from North of Iran. سامانه مدیریت نشریات علمی, 9(Special), 107-114. doi: 10.22092/jmpb.2020.121757
Seyed Mohammad Vahdat; Maryam Khavarpour; Sohrab Kazemi. "Chemical Composition, Antimicrobial and Analgesic Properties of Rosmarinus officinalis L. from North of Iran". سامانه مدیریت نشریات علمی, 9, Special, 1398, 107-114. doi: 10.22092/jmpb.2020.121757
Vahdat, Seyed Mohammad, Khavarpour, Maryam, Kazemi, Sohrab. (1398). 'Chemical Composition, Antimicrobial and Analgesic Properties of Rosmarinus officinalis L. from North of Iran', سامانه مدیریت نشریات علمی, 9(Special), pp. 107-114. doi: 10.22092/jmpb.2020.121757
Vahdat, Seyed Mohammad, Khavarpour, Maryam, Kazemi, Sohrab. Chemical Composition, Antimicrobial and Analgesic Properties of Rosmarinus officinalis L. from North of Iran. سامانه مدیریت نشریات علمی, 1398; 9(Special): 107-114. doi: 10.22092/jmpb.2020.121757

Chemical Composition, Antimicrobial and Analgesic Properties of Rosmarinus officinalis L. from North of Iran

Journal of Medicinal plants and By-products
دوره 9، Special، خرداد 2020، صفحه 107-114    اصل مقاله (738.39 K)
شناسه دیجیتال (DOI): 10.22092/jmpb.2020.121757
نویسندگان
Seyed Mohammad Vahdat* 1؛ Maryam Khavarpour2؛ Sohrab Kazemi3
1Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
2Department of Chemical Engineering, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
3Cellular and Molecular Biology Research Center, Babol University of Medical Sciences, Babol, Iran
چکیده
Medicinal plants can be used in food, pharmaceutical and cosmetic products due to their biological and nutritional properties. The objective of this research was to examine the chemical composition, antimicrobial and analgesic activity of Rosmarinus officinalis L. plant originating Amol, north of Iran for the first time. The essential oil was obtained by hydrodistillation. Gas chromatography-mass spectrometry study was used for oil analysis. Staphylococcus aureus, Escherichia coli, Salmonella enteritidis, Bacillus subtilis and Candida albicans were used to examine the antimicrobial activity of the essential oils using agar disk diffusion assay. GC-MS analysis revealed that the oil was dominated by 1,8-cineole (20.20%), α-Pinene (17.29%) and borneol (7.59%). Antimicrobial assays of different dilutions of essential oil showed significant antimicrobial activity against gram-positive bacteria. Furthermore, the water and ethanolic extracts prevented the pain resulting from hot-plate test. The results suggested Rosmarinus officinalis from Amol as an alternative natural compound which has antimicrobial and analgesic effects to use in pharmaceutical industries. 
کلیدواژه‌ها
Analgesic؛ Antimicrobial Activity؛ Chemical Composition؛ Essential Oil؛ Extract؛ Rosmarinus officinalis
مراجع

1. Jaimand K, Rezaee MB, Homami S. Comparison Extraction Methods of Essential oils of Rosmarinus officinalis L. in Iran By Microwave Assisted Water Distillation; Water Distillation and Steam Distillation. J Med Plant By-prod. 2018;1:9-14.

2. Szumny A, Figiel A, Gutiérrez-Ortíz A, Carbonell-Barrachina ÁA. Composition of rosemary essential oil (Rosmarinus officinalis) as affected by drying method. J Food engineer. 2010;97:253-260.

3. Benincá JP, Dalmarco JB, Pizzolatti MG, Fröde T. Analysis of the anti-inflammatory properties of Rosmarinus officinalis L. in mice. Food Chem. 2011;124:468-475.

4. Alipour M,Saharkhiz MJ. Phytotoxic activity and variation in essential oil content and composition of Rosemary (Rosmarinus officinalis L.) during different phenological growth stages. Biocatal. Agri Biotechnol. 2016;7:271-278.

5. Doğan S, Diken ME, Turhan Y, Alan U, Dog˘an M, Alkan M. Characterization and inhibition of Rosmarinus officinalis L. polyphenoloxidase. Eur Food Res Technol. 2011;233:293-301.

6. Rahbardar MG, Amin B, Mehri S, Mirnajafi-Zadeh SJ, Hosseinzadeh H. Anti-inflammatory effects of ethanolic extract of Rosmarinus officinalis L. and rosmarinic acid in a rat model of neuropathic pain. Biomed Pharmacother. 2017;86:441-449.

7. Altinier G, Sosa S, Aquino RP, Mencherini T, Loggia RD, Tubaro A.  Characterization of topical antiinflammatory compounds in Rosmarinus officinalis L. J Agric Food Chem. 2007;55:1718-1723.

8. Bozin B,Mimica-Dukic N, Samojlik I, Jovin E. Antimicrobial and antioxidant properties of rosemary and sage (Rosmarinus officinalis L. and Salvia officinalis L., Lamiaceae) essential oils. J Agric Food Chem. 2007;55:7879-7885.

9. Campo JD, Amiot MJ, Nguyen-The C. Antimicrobial effect of rosemary extracts. J. food prot. 2000;63:1359-1368.

10. Beretta G,Artali R, Facino RM, Gelmini F. An analytical and theoretical approach for the profiling of the antioxidant activity of essential oils: The case of Rosmarinus officinalis L. J Pharm Biomed Anal. 2011;55:1255-1264.

11. Machado DG, Cunha VB, Neis GO, Balen A, Colla LE, Bettio A, Oliveira FL, Pazini J.B, et al. Antidepressant-like effects of fractions, essential oil, carnosol and betulinic acid isolated from Rosmarinus officinalis L. Food Chem. 2013;136:999-1005.

12. Ghasemzadeh RahbardarM, Amin B, Mehri S, MirnajafiZadeh SJ, Hosseinzadeh H. Effect of alcoholic extract of aerial parts of Rosmarinus officinalis L. on pain, inflammation and apoptosis induced by chronic constriction injury (CCI) model of neuropathic pain in rats. J Ethnopharmacol. 2016;194:117-130.

13. Abdel-Wahhab KGED, El-Shamy KA, El-Beih NAEZ, Morcy FA, Mannaa FAE, Protective effect of a natural herb (Rosmarinus officinalis) against hepatotoxicity in male albino rats. Com Sci. 2011;2:9-17.

14. Diaz‐Maroto M, Pérez-Coello MS, Sánchez-Palomo E, González-Viñas MA. Impact of drying and storage time on sensory characteristics of rosemary (Rosmarinus officinalis L.). J Sens Stud. 2007;22:34-48.

15. Ladan Moghadam AR, Antioxidant activity and chemical composition of Rosmarinus officinalis L. essential oil from Iran. J Essen Oil Bear. Pl. 2015;18:1490-1494.

16. Tuttolomondo T, Dugo G, Ruberto G, Leto C, Napoli EM, Cicero N, Gervasi T, Virga G, Leone R, Licata M, La Bella S. Study of quantitative and qualitative variations in essential oils of Sicilian Rosmarinus officinalis L. Nat Prod Res. 2015;29:1928-1934.

17. Ben Jemia M, Tundis R, Pugliese A, Menichini F, Senatore F, Bruno M, Elyes Kchouk M, Loizzo MR. Effect of bioclimatic area on the composition and bioactivity of Tunisian Rosmarinus officinalis essential oils. Nat Prod Res. 2015;29:213-222.

18. Maggi M, Gende L, Russo K, Fritz R, Eguaras  M. Bioactivity of Rosmarinus officinalis essential oils against Apis mellifera, Varroa destructor and Paenibacillus larvae related to the drying treatment of the plant material. Nat Prod Res. 2011;25:397-406.

19. Saeidnia S, Gohari AR, Mokhaber-Dezfuli N, Kiuchi F. A review on phytochemistry and medicinal properties of the genus Achillea. DARU. 2011;19:173.

20. Ivanovic J, Misic D, Zizovic I, Ristic M.  In vitro control of multiplication of some food-associated bacteria by thyme, rosemary and sage isolates. Food Control. 2012;25:110-116.

21. Jordán MJ, Lax V, Rota MC, Lorán S, Sotomayor JA.  Effect of bioclimatic area on the essential oil composition and antibacterial activity of Rosmarinus officinalis L. Food Control. 2013;30:463-468.

22. McLafferty FW. The Wiley/NBS registry of mass spectral data. 1989.

23. Adams RP. Identification of essential oil components by gas chromatography/mass spectrometry. Vol. 456. Allured publishing corporation Carol Stream, IL.2007.

24. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 1983;16:109-110.

25. King MA, Bradshaw S, Chang AH, Pintar GW. Potentiation of Opioid Analgesia in Dopamine2Receptor Knock-Out Mice: Evidence for a Tonically Active Anti-Opioid System. J Neurosci. 2001;21:7788-7792.

26. Mahdian F, Mahboubi M, Rahimi E, Moslehi Shad M.  Chemical Composition and Antimicrobial Activity of the Essential Oil of Tanacetum persicum. Jundishapur J Nat Pharm Prod. 2016;12.

27. Burt S. Essential oils: their antibacterial properties and potential applications in foods—a review. Int J Food Microbiol. 2004;94:223-253.

28. Hajhashemi V, Ghannadi A, Sharif B. Anti-inflammatory and analgesic properties of the leaf extracts and essential oil of Lavandula angustifolia Mill. J Ethnopharmacol. 2003;89:67-71.

29. Santos F, Rao V. Antiinflammatory and antinociceptive effects of 1, 8‐cineole a terpenoid oxide present in many plant essential oils. Phytother Res. 2000;14:240-244.

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