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Effect of Taxus baccata L. Extract on Hydatid Cyst Protoscolices In vitro | ||
| Archives of Razi Institute | ||
| مقاله 7، دوره 75، شماره 4، اسفند 2020، صفحه 473-480 اصل مقاله (377.47 K) | ||
| نوع مقاله: Original Articles | ||
| شناسه دیجیتال (DOI): 10.22092/ari.2019.125573.1310 | ||
| نویسندگان | ||
| R. Norouzi* 1؛ M. Hejazy2؛ D. Azizi2؛ A. Ataei1 | ||
| 1Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran | ||
| 2Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran | ||
| چکیده | ||
| Hydatidosis is the most important global parasitic infectious disease both in humans and animals, which can lodge at different organs of the host, such as liver, lung (even heart), and brain which may lead to death. Surgery is the main method for the treatment of hydatidosis. In surgical therapy of hydatidosis, the use of sporicidal agents is very important since these agents inactivate live protoscolices and prevent recurrence of infection. Presently, numerous scolicidal chemical agents have been administrated to inactivate the hydatid cyst contents. Recently, there has been a high tendency among researchers to evaluate and present herbal plants as alternative option due to inexpensiveness, availability, low side effects, and toxicity. This study aimed to evaluate the scolicidal effect of hydro alcoholic Taxus baccata L. extract in vitro for the first time. The scolicidal activities of the extract were tested in concentrations of 50, 100, and 150 mg/ml following 10, 30, and 60 min of incubation, and the experiments were performed in triplicate. Viability of protoscolices was confirmed by 0.1% eosin vital staining. The data were analyzed in SAS software (version 9.4). The results showed that the hydroalcoholic extract of Taxus baccata L. at the concentration of 150 mg/ml led to killing 66.6% of protoscolices at 60 min. according to the results of this investigation, it is recommended to use this plant as a scolicidal plant. The findings of the present study showed that Taxus baccata L. had potent scolicidal effects. However, further studies are required to evaluate the efficacy of Taxus baccata L. in vivo. | ||
| کلیدواژهها | ||
| Hydatid cyst؛ In vitro؛ Scolicidal؛ Taxus baccata L | ||
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| مراجع | ||
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Adas, G., Arikan, S., Kemik, O., Oner, A., Sahip, N., Karatepe, O., 2009. Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study). World J Gastroenterol 15, 112-116.
Anthony, J.P., Fyfe, L., Smith, H., 2005. Plant active components - a resource for antiparasitic agents? Trends Parasitol 21, 462-468.
Daniel-Mwuambete, K., Ponce-Gordo, F., Torrado, J., Torrado, S., Cuesta-Bandera, C., 2003. Effect of two formulations of benzimidazole carbamates on the viability of cysts of Echinococcus granulosus in vivo. Parasite 10, 371-373. Elissondo, M.C., Albani, C.M., Gende, L., Eguaras, M., Denegri, G., 2008. Efficacy of thymol against Echinococcus granulosus protoscoleces. Parasitol Int 57, 185-190.
Erdemoglu, N., Sener, B., 2001. Antimicrobial activity of the heartwood of Taxus baccata. Fitoterapia 72, 59-61.
Esmailzadeh, O., Hosseini, S.M., Tabari, M., 2007. A Phytosociological Study of English Yew (Taxus baccata L.) in Afratakhteh Reserve. Pajouhesh & Sazandegi, 74, 17-24.
Fasihi Harandi, M., Budke, C.M., Rostami, S., 2012. The monetary burden of cystic echinococcosis in Iran. PLoS Neglect Trop Dis 6, e1915.
Kavoosi, G., Purfard, A.M., 2013. Scolicidal effectiveness of essential oil from Zataria multiflora and Ferula assafoetida: disparity between phenolic monoterpenes and disulphide compounds. Comp Clin Path 22, 999-1005.
Mahmoudvand, H., Dezaki, E.S., Kheirandish, F., Ezatpour, B., Jahanbakhsh, S., Harandi, M.F., 2014. Scolicidal effects of black cumin seed (Nigella sativa) essential oil on hydatid cysts. Korean J Parasitol 52, 653-659.
Moazeni, M., Larki, S., Oryan, A., Saharkhiz, M.J., 2014. Preventive and therapeutic effects of Zataria multiflora methanolic extract on hydatid cyst: An in vivo study. Vet Parasitol 205, 107-112.
Moazeni, M., Larki, S., Pirmoradi, G., Rahdar, M., 2015. Scolicidal effect of the aromatic water of Zataria multiflora: an in vitro study. Comp Clin Path 24, 1057-1062.
Moazeni, M., Saharkhiz, M.J., Hoseini, A.A., Alavi, A.M., 2012. In vitro scolicidal effect of Satureja khuzistanica (Jamzad) essential oil. Asian Pac J Trop Biomed 2, 616-620.
Moro, P., Schantz, P.M., 2009. Echinococcosis: a review. Int J Infect Dis 13, 125-133.
Otero-Abad, B., Torgerson, P.R., 2013. A systematic review of the epidemiology of echinococcosis in domestic and wild animals. PLoS Neglect Trop Dis 7, e2249.
Rouhani, S., Athari, A., Kianian, H., 2001. Prevalence of intestinal parasites in villages of Sari. J Zanjan Univ Med Sci 34, 33-40.
Rouhani, S., Salehi, N., Kamalinejad, M., Zayeri, F., 2013. Efficacy of Berberis vulgaris aqueous extract on viability of Echinococcus granulosus protoscolices. J Invest Surg 26, 347-351.
Sadjjadi, S.M., Zoharizadeh, M.R., Panjeshahin, M.R., 2008. In vitro screening of different Allium sativum extracts on hydatid cysts protoscoleces. J Invest Surg 21, 318-322.
Valadbeigi, T., Shaddel, M., 2014. Antibacterial and Antifungal Activities of Different lichens Extracts. Clin Microbiol Infect 2, 71-75.
Valadbeigi, T., Shaddel, M., 2015. Antibacterial and Antifungal Activities of Gelatinose and non-Gelatinose Lichen Species. J Arch Mil Med 3, e31610.
Valadbeigi, T., Shaddel, M., 2016. Amylase inhibitory activity of some macrolichens in Mazandaran province, Iran. Physiol Pharmacol 20, 215-219. | ||
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