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Effectiveness of Thermostable Vaccine for Newcastle Disease Produced by the Razi Institute on Backyard Poultry in Iran during 2015 | ||
| Archives of Razi Institute | ||
| مقاله 3، دوره 75، شماره 1، خرداد 2020، صفحه 1-7 اصل مقاله (156.8 K) | ||
| نوع مقاله: Original Articles | ||
| شناسه دیجیتال (DOI): 10.22092/ari.2018.120709.1199 | ||
| نویسندگان | ||
| M.H. Fallah Mehrabadi1؛ S.A. Ghafouri* 2؛ A. Shoushtari1؛ F. Tehrani1؛ S. Masoudi1؛ M. Abdoshah1؛ S. Amir Hajloo3؛ M. Shabani3 | ||
| 1Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization, Tehran, Iran | ||
| 2Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran | ||
| 3Department of Health and Management of Poultry Diseases, Iranian Veterinary Organization, Tehran, Iran | ||
| چکیده | ||
| Newcastle disease causes many economic losses to the poultry industry in most countries. This disease is endemic in Iran. Backyard poultry is considered the reservoir of Newcastle virus; however, there is either no vaccination program against Newcastle, or it is performed in a restricted manner. Commercial live vaccines are inactive and sensitive to temperature; moreover, vaccine delivery to villages and remote areas requires special equipment and high cost to maintain the cold chain. This study evaluated the effectiveness of a thermostable Newcastle vaccine produced by the Razi Institute (ND.TR.IR) on the backyard poultry. In four provinces, at least 4 villages were selected as the treatment group, and the same number was selected as the control group. At least, 30 birds were sampled in each village. In each group, blood samples were collected before vaccination and 2 weeks later, and the serum titer of the samples was examined with the haemagglutination inhibition test. The arithmetic mean and standard deviation of the sample titers at the rural level were compared using paired t-test before and after vaccination in each group. Moreover, Repeated Measures ANOVA was utilized to compare the vaccinated and control groups in terms of the titer changes before and after vaccination. In this study, 584 and 389 samples were taken from the treatment (53 households in 20 villages) and control groups (33 households in 14 villages). The mean serum titer values of Newcastle were 4.51±3.03 and 6.64±2.48 in the treatment group before and after vaccination, respectively (p <0.001). The increase in mean titer of the treatment group (2.31 log) was statistically higher than that in the control group (0.66 log) (p <0.001). Out of 584 birds, 517 (88.5%) ones had titer above 3 in the second turn in the treatment group. The thermostable vaccine (ND.TR.IR) produced by the Razi institute is suitable for backyard poultry, which immunizes them against Newcastle disease. Appropriate vaccination programs for backyard poultry should be made; moreover, vaccination of backyard poultry can be effective in preventing the circulation of the field viruses. | ||
| کلیدواژهها | ||
| Backyard poultry؛ Effectiveness؛ Haemagglutination inhibition (HI)؛ ND.TR.IR vaccine؛ Newcastle disease | ||
| عنوان مقاله [English] | ||
| ارزیابی اثربخشی واکسن زنده مقاوم به حرارت بیماری نیوکاسل (ND.TR.IR) ساخت موسسه رازی در طیور بومی در ایران در سال 1394 | ||
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| مراجع | ||
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Abah, H., Abdu, P.A., Sa’idu, L., 2017. Vaccination of chickens with thermostable newcastle disease vaccine I2 coated on processed grains and offals scholars. J Agr Vet Sci 4, 138-145.
Abdoshah, M., Pourbakhsh, S., Peighambari, S., Shojadoost, B., Momayez, R., Mojahedi, Z., 2012. Pathogenicity indices of Newcastle disease viruses isolated from Iranian poultry flocks in Iran. J Vet Res 67, 159-164.
Adwar, T., Lukesova, D., 2008. Evaluation of thermostable vaccines against Newcastle disease in village chicken used in tropics and subtropics. Agric Trop Subtrop 41, 74-79.
Alders, R., Spradbrow, P., 2001. Controlling Newcastle disease in village chickens: a field manual, Australian Centre for International Agricultural Research (ACIAR), Australian.
Alders, R.G., 2014. Making Newcastle disease vaccines available at village level. Vet Record 174, 502-503.
Alexander, D., 1995. The epidemiology and control of avian influenza and Newcastle disease. J Compar Pathol 112, 105-126.
Awan, M.A., Otte, M., James, A., 1994. The epidemiology of Newcastle disease in rural poultry: a review. Avian Pathol 23, 405-423.
Bell, J., Fotzo, T., Amara, A., Agbede, G., 1995. A field trial of the heat resistant V4 vaccine against Newcastle disease by eye-drop inoculation in village poultry in Cameroon. Prev Vet Med 25, 19-25.
Bensink, Z., Spradbrow, P., 1999. Newcastle disease virus strain I2–a prospective thermostable vaccine for use in developing countries. Vet Microbiol 68, 131-139.
Dimitrov, K.M., Afonso, C.L., Yu, Q., Miller, P.J., 2017. Newcastle disease vaccines—A solved problem or a continuous challenge? Vet Microbiol 206, 126-136.
Hosseini, H., Langeroudi, A.G., Torabi, R., 2014. Molecular characterization and phylogenetic study of Newcastle disease viruses isolated in Iran, 2010–2012. Avian Dis 58, 373-376.
Jagne, J., Aini, I., Schat, K., Fennell, A., Touray, O., 1991. Vaccination of village chickens in The Gambia against Newcastle disease using the heat‐resistant, food‐pelleted V4 vaccine. Avian Pathol 20, 721-724.
Mehrabadi, M.F., Bahonar, A., Marandi, M.V., Sadrzadeh, A., Tehrani, F., Salman, M., 2016. Sero-survey of Avian Influenza in backyard poultry and wild bird species in Iran—2014. Prev Vet Med 128, 1-5.
Najjari, A.A., Nili, H., Asasi, K., Mosleh, N., Rohollahzadeh, H., Mokhayeri, S., 2017. Efficacy of thermostable I-2 Newcastle disease vaccine compared to B1 commercial vaccine in broiler chicken. Iran J Vet Res 18, 103-107.
OIE, A., 2017. Manual of diagnostic tests and vaccines for terrestrial animals, Office international des epizooties, Paris, France.
Saif, Y., Fadly, A., Glisson, J., McDougald, L., 2008. Newcastle disease, other avian paramyxoviruses, and pneumovirus infections. Dis Poultry 2, 75-93.
Van Borm, S., Thomas, I., Hanquet, G., Lambrecht, B., Boschmans, M., Dupont, G., et al., 2005. Highly pathogenic H5N1 influenza virus in smuggled Thai eagles, Belgium. Emerg Infect Dis 11, 702-705.
Van Boven, M., Bouma, A., Fabri, T.H., Katsma, E., Hartog, L., Koch, G., 2008. Herd immunity to Newcastle disease virus in poultry by vaccination. Avian Pathol 37, 1-5. | ||
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