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تأثیر مکمل جینکو بیلوبا (Ginkgo biloba L.) بر ظرفیت آنتی‌اکسیدانی تام و شاخص مالون‌دی‌آلدئید پس از یک جلسه فعالیت ورزشی هوازی در زنان غیر فعال | ||
| تحقیقات گیاهان دارویی و معطر ایران | ||
| مقاله 5، دوره 34، شماره 3 - شماره پیاپی 89، مرداد و شهریور 1397، صفحه 401-411 اصل مقاله (656.7 K) | ||
| نوع مقاله: مقاله پژوهشی | ||
| شناسه دیجیتال (DOI): 10.22092/ijmapr.2018.116015.2173 | ||
| نویسنده | ||
| سیروان آتشک* | ||
| دانشیار، گروه فیزیولوژی ورزشی، واحد مهاباد، دانشگاه آزاد اسلامی، مهاباد، ایران | ||
| چکیده | ||
| این تحقیق به‌منظور تعیین تأثیر مکمل‌سازی کوتاه مدت جینکو بیلوبا (Ginkgo biloba L.) بر مقادیر ظرفیت آنتی‌اکسیدانی تام (TAC) و مالون‌دی‌آلدئید (MDA) متعاقب یک جلسه فعالیت هوازی، در زنان غیر ورزشکار انجام شد. در یک مطالعه نیمه تجربی با اندازه‌گیری‌های مکرر 24 زن سالم غیر ورزشکار در دو گروه دریافت‌کننده مکمل جینکو بیلوبا (120 میلی‌گرم به مدت 21 روز قرص جینکو بیلوبا) و شبه دارو (120 میلی‌گرم به مدت 21 روز دکستروز) قرار گرفتند. قبل و بعد از دوره مکمل‌سازی، همه آزمودنی‌ها در یک آزمون ورزشی هوازی بر روی نوارگردان با شدت 75% اکسیژن مصرفی بیشینه به مدت 30 دقیقه شرکت نمودند. نمونه‌های خونی در چهار مرحله 1) در حالت پایه قبل از شروع مکمل‌سازی، 2) بلافاصله پس از انجام آزمون ورزشی، 3) بعد از دوره مکمل‌سازی و 4) بعد از اجرای آزمون ورزشی دوم برای اندازه‌گیری ظرفیت TAC و MDA جمع‌آوری شد. داده‌های حاصل با استفاده از آزمون تحلیل واریانس (ANOVA) با اندازه‌گیری‌های مکرر و آزمون تعقیبی LSD در سطح معنی‌داری 0.05≥α بررسی شد. یافته‌ها نشان داد که آزمون هوازی باعث افزایش معنی‌دار غلظت MDA و کاهش معنی‌دار TAC می‌گردد (05/0>P). با این حال، مصرف کوتاه مدت جینکو بیلوبا باعث افزایش معنی‌دار TAC در حالت پایه در گروه دریافت‌کننده مکمل شد (0.017=P). به‌علاوه دامنه MDA در گروه دریافت‌کننده مکمل جینکو بیلوبا پس از انجام فعالیت ورزشی به‌طور معنی‌داری کمتر از گروه شبه دارو بود (0.023=P). این یافته‌ها نشان داد که فعالیت هوازی می‌تواند باعث افزایش برخی شاخص‌های فشار اکسایشی شود، اما مصرف مکمل جینکو بیلوبا احتمالاً از طریق افزایش TAC می‌تواند از بروز استرس اکسایشی ناشی از ورزش بکاهد، با این حال توصیه می‌شود برای مشخص شدن اثرات واقعی این مکمل گیاهی تحقیقات بیشتری انجام شود. | ||
| کلیدواژه‌ها | ||
| جینکو بیلوبا (Ginkgo biloba L.)؛ فعالیت هوازی؛ زنان غیرفعال؛ ظرفیت آنتی‌اکسیدانی تام؛ مالون‌دی‌آلدئید | ||
| عنوان مقاله [English] | ||
| Effect of Ginkgo biloba L. on total antioxidant capacity and malondialdehyde after aerobic exercise in inactive women | ||
| نویسندگان [English] | ||
| S. Atashak | ||
| Department of Exercise Physiology, Mahabad Branch, Islamic Azad University, Mahabad, Iran | ||
| چکیده [English] | ||
| This study was conducted to determine the effect of short-term Ginkgo biloba L. on total antioxidant capacity (TAC) and malondialdehyde (MDA) after an aerobic exercise in inactive women. In a quasi-experimental study, twenty-four non-athlete women were allocated into a supplement (120mg/day Ginkgo biloba for 21 days) and placebo groups (120mg/day dextrose for 21 days). All the subjects participated in aerobic exercise protocol with 75% VO2 max on the treadmill for 30 minutes in pre and after supplementation. Venous blood samples were collected to assess the capacity of the TAC and MDA in four phases; 1) at the baseline 2) immediately after exercise test 3) after supplementation and 4) after supplementation and the second exercise test. Dates were analyzed by repeated measure ANOVA and LSD post-hoc test at α≤0.05. The results showed that MDA concentration increased, but TAC decreased significantly after aerobic exercise (P<0.05). However, short-term Ginkgo biloba supplementation led to a significant increase in baseline serum TAC in the supplement group (P= 0.017). Moreover, the increase in the MDA concentration in the supplement group was significantly more than that in the placebo group (P= 0.023). The results showed that aerobic exercise could increase some oxidative stress indices, but, short-term Ginkgo biloba supplementation probably could reduce the exercise-induced oxidative stress by increasing TAC. However, but more research is needed to determine the real effects of this herbal supplement. | ||
| کلیدواژه‌ها [English] | ||
| Ginkgo biloba L, aerobic exercise, inactive women, total antioxidant capacity, malondialdehyde | ||
| مراجع | ||
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