| تعداد نشریات | 282 |
| تعداد نشریات سازمان | 80 |
| تعداد شماره‌ها | 3,251 |
| تعداد مقالات | 35,917 |
| تعداد مشاهده مقاله | 54,566,050 |
| تعداد دریافت فایل اصل مقاله | 93,689,441 |
Comparative Evaluation of the Biochemical Effects of Ketamine plus Ketoprofen and Midazolam in the Premedication of Pigeons | ||
| Archives of Razi Institute | ||
| مقاله 7، دوره 73، شماره 3، آذر 2018، صفحه 223-227 اصل مقاله (109.79 K) | ||
| نوع مقاله: Original Articles | ||
| شناسه دیجیتال (DOI): 10.22092/ari.2017.109066.1099 | ||
| نویسندگان | ||
| H. Hajizadeh1؛ G. Abedi* 1؛ A. Asghari1؛ S. Hesaraki2 | ||
| 1Department of Veterinary Surgery, Faculty of Veterinary Medicine, Science and Research Branch, Islamic Azad University, Tehran, Iran | ||
| 2Department of Pathology, Faculty of Veterinary Medicine, Science and Research Branch, Islamic Azad University, Tehran, Iran | ||
| چکیده | ||
| The present study was conducted with the aim of comparing the effects of premedication with ketoprofen and midazolam in birds. A total of 24 male pigeons with an approximate weight of 300 g were divided into four equal groups. The control group (Group I) was injected with ketamine alone. Groups II-IV were injected with ketoprofen alone, ketoprofen+ketamine, and midazolam+ketamine, respectively. The biochemical changes in the four groups were evaluated after intramuscular drug injections at different anesthetic levels. A record of biochemical changes was maintained for each group. Blood samples were taken before and after the administration of the medications in order to measure the levels of serum alkaline phosphatase (ALP), oxaloacetate transaminase (OT), prothrombin time (PT), glucose (GLU), lactate dehydrogenase (LDH), albumin (Alb), total protein (TP), and gamma-glutamyl transferase (GGTF). The results showed significant differences in the mean levels of ALP, OT, PT, GLU, LDH, Alb, and TP after anesthesia, compared to that before anesthesia. Therefore, ketoprofen+ketamine can be used for the induction of anesthesia in birds.The present study was conducted with the aim of comparing the effects of premedication with ketoprofen and midazolam in birds. A total of 24 male pigeons with an approximate weight of 300 g were divided into four equal groups. The control group (Group I) was injected with ketamine alone. Groups II-IV were injected with ketoprofen alone, ketoprofen+ketamine, and midazolam+ketamine, respectively. The biochemical changes in the four groups were evaluated after intramuscular drug injections at different anesthetic levels. A record of biochemical changes was maintained for each group. Blood samples were taken before and after the administration of the medications in order to measure the levels of serum alkaline phosphatase (ALP), oxaloacetate transaminase (OT), prothrombin time (PT), glucose (GLU), lactate dehydrogenase (LDH), albumin (Alb), total protein (TP), and gamma-glutamyl transferase (GGTF). The results showed significant differences in the mean levels of ALP, OT, PT, GLU, LDH, Alb, and TP after anesthesia, compared to that before anesthesia. Therefore, ketoprofen+ketamine can be used for the induction of anesthesia in birds. | ||
| کلیدواژه‌ها | ||
| Serum Analysis؛ Ketamine؛ Ketoprofen؛ Midazolam؛ Pigeons | ||
| عنوان مقاله [English] | ||
| ارزیابی مقایسه ای تأثیر تجویز پیش دارویی بیومکانیک کتوپروفن و میدازولام با کتامین در کبوتر | ||
| نویسندگان [English] | ||
| هادی حاجی‌زاده1؛ غلامرضا عابدی1؛ احمد اصغری1؛ سعید حصارکی2 | ||
| 1گروه جراحی دامپزشکی، دانشکده دامپزشکی، واحد علوم و تحقیقات، دانشگاه آزاد اسلامی، تهران، ایران | ||
| 2گروه آسیب شناسی، دانشکده دامپزشکی، واحد علوم و تحقیقات، دانشگاه آزاد اسلامی، تهران، ایران | ||
| چکیده [English] | ||
| این مطالعه با هدف مقایسه اثرات کتوپروفن و میدازولام به عنوان پیش دارو در پرندگان انجام شده است. 24 کبوتر نر با وزن تقریبی 300 گرم به چهار گروه شش تایی تقسیم شدند. در گروه کنترل (گروه 1)، تنها کتامین تزریق شد. در گروه 2، تنها کتوپروفن تزریق شد. در گروه 3، کتوپروفن و کتامین استفاده شد. در گروه چهار، میدازولام و کتامین تزیرق شد. تغییرات بیومکانیک پس از تزریق عضلانی دارو در سطوح بیهوشی مختلف به کبوتران مورد ارزیابی قرار گرفت. تغییرات بیومکانیک در هر گروه ثبت گردید. نمونه خون قبل و بعد از تجویز برای اندازه کیری سطح آلکالین فسفاتاز، اگزالات ترانس آمیناز، زمان پروترومبین، گلوکز، لاکتات دهیدروژناز، آلبومین، آلبومین کل و گاما گلوتامیل ترانسفراز گرفته شد. پارامترهای بیومکانیک مختلف اندازه گیری شده در چهار گروه، نشان دهنده تفاوت های معنادار (P>0.5) در مقادیر متوسط آلکالین فسفاتاز، اگزالات ترانس آمیناز، زمان پروترومبین، گلوکوز، لاکتات دهیدروژناز، آلبومین و پروتیین کل بود. کتوپروفن به اضافه کتامین میتواند به عنوان داروی انتخابی در بیهوشی پرندگان استفاده شود. | ||
| کلیدواژه‌ها [English] | ||
| آنالیز سرمی, پرندگان, کتامین, کتوپروفن, میدازولام, کبوتران | ||
| مراجع | ||
|
Azizpour, A., Hassani, Y., 2012. Clinical Evaluation of General Anesthesia with a Combination of Ketamine HCL and Diazepam in Pigeons. Agri J 7, 101-105.
Bonina, F., Puglia, C., Santagati, N.A., Saija, A., Tomaino, A., Tita, B., 2002. Oligoethylene ester derivatives of ketoprofen, naproxen and diclofenac as oral prodrugs: a pharmacological evaluation. Pharmazie 57, 552-555.
Dubois, R.N., Abramson, S.B., Crofford, L., Gupta, R.A., Simon, L.S., Van De Putte, L.B., et al., 1998. Cyclooxygenase in biology and disease. FASEB J 12, 1063-1073.
Forbes, N.A., 1998. Avian Anesthesia. Veterinary Quarterly 20, S65-S66.
Forsyth, S.F., Guilford, W.G., Lawoko, C.R., 1996. Endoscopic evaluation of the gastroduodenal mucosa following non-steroidal anti-inflammatory drug administration in the dog. N Z Vet J 44, 179-181.
Gali, J.C., Sansanovicz, D., Ventin, F.C., Paes, R.H., Quevedo, F.C., Caetano, E.B., 2014. Dipyrone has no effects on bone healing of tibial fractures in rats. Acta Ortop Bras 22, 210-213.
Garcia Rodriguez, L.A., Varas-Lorenzo, C., Maguire, A., Gonzalez-Perez, A., 2004. Nonsteroidal antiinflammatory drugs and the risk of myocardial infarction in the general population. Circulation 109, 3000-3006.
Garcı́a Rodrı́guez, L.A.M.D., 1998. Variability in Risk of Gastrointestinal Complications With Different Nonsteroidal Anti-inflammatory Drugs 1. The American Journal of Medicine 104, 30S-34S.
Hernández-Díaz, S., Rodríguez, L., 2000. Association between nonsteroidal anti-inflammatory drugs and upper gastrointestinal tract bleeding/perforation: An overview of epidemiologic studies published in the 1990s. Archives of Internal Medicine 160, 2093-2099.
Kamiloglu, A., Atalan, G., Kamiloglu, N.N., 2008. Comparison of intraosseous and intramuscular drug administration for induction of anaesthesia in domestic pigeons. Res Vet Sci 85, 171-175.
Kang, J.Y., Khan, M.N., Park, N.H., Cho, J.Y., Lee, M.C., Fujii, H., et al., 2008. Antipyretic, analgesic, and anti-inflammatory activities of the seaweed Sargassum fulvellum and Sargassum thunbergii in mice. J Ethnopharmacol 116, 187-190.
Kore, A.M., 1990. Toxicology of Nonsteroidal Antiinflammatory Drugs. Veterinary Clinics of North America: Small Animal Practice 20, 419-430.
Maiti, S.K., Tiwary, R., Vasan, P., Dutta, A., 2006. Xylazine, diazepam and midazolam premedicated ketamine anaesthesia in White Leghorn cockerels for typhlectomy. 2006 77, 7.
Reuter, B.K., Asfaha, S., Buret, A., Sharkey, K.A., Wallace, J.L., 1996. Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2. J Clin Invest 98, 2076-2085.
Roughan, J.V., Paul, A.F., 2001. Behavioural effects of laparotomy and analgesic effects of ketoprofen and carprofen in rats. Pain 90.
Sandmeier, P., 2000. Evaluation of Medetomidine for Short-Term Immobilization of Domestic Pigeons (Columba livia) and Amazon Parrots (Amazona species). Journal of Avian Medicine and Surgery 14, 8-14.
Semrad, S.D., 1993. Comparative efficacy of flunixin, ketoprofen, and ketorolac for treating endotoxemic neonatal calves. Am J Vet Res 54, 1511-1516.
Vane, J.R., Botting, R.M., 1995. New insights into the mode of action of anti-inflammatory drugs. Inflamm Res 44.
Yayla, S., Kacar, C., Kaya, D., Merhan, O., Aksoy, O., Kilic, E., et al., 2012. Clinical, Biochemical and Haemodynamic Effects of the Intrathecal Ketamine for Ovariohysterectomy in Bitches. 56, 299.
Yuen, V.M., Hui, T.W., Irwin, M.G., Yuen, M.K., 2008. A comparison of intranasal dexmedetomidine and oral midazolam for premedication in pediatric anesthesia: a double-blinded randomized controlled trial. Anesth Analg 106, 1715-1721. | ||
|
آمار تعداد مشاهده مقاله: 2,118 تعداد دریافت فایل اصل مقاله: 2,968 |
||