Comparison of antimicrobial effect of Ruta graveolens and gentamicin against Pseudomonas aeruginosa | ||
| تحقیقات گیاهان دارویی و معطر ایران | ||
| Article 5, Volume 20, Issue 2 - Serial Number 24, July 2004, Pages 171-180 PDF (4.02 M) | ||
| Document Type: Research Paper | ||
| Authors | ||
| P. Owlia* 1; H. Saderi1; S.A. Tabatabaei Nezhad1; M. Naseri1; M.B. Rezaee2 | ||
| 1Faculty of Medicine, Shahed University, P. O. Box 14155- 7435, Tehran, Iran | ||
| 2Research Institute of Forests and Ranglands | ||
| Abstract | ||
| Pseudomonas aeruginosa is important opportunistic pathogen and to produce widespread infections by numerous virulence factors. Treatment of Pseudomonas infection is very difficult, because resistance to antibiotics is increasing. The purpose of this study was evaluation of antimicrobial effects of extract of Ruta graveolens on P. aeruginosa (28852ATCC). MIC and MBC of extract were evaluated and change of number of bacteria in the present of 1%, 2%, 4% and 8% of R. graveolens extract was compared with the change of number of bacteria in the present of 0.00078 and 0.00156mg/ml gentamicin. The results showed that MIC and MBC of R. graveolenc extract were equal of 10% of concentration. Comparison of change of number of bacteria had shown that the effect of 8% of extract of R. graveolens after 4 h is equal of 0.00156mg/ml gentamicin after 2h. According to the results we can probably to use of R. graveolens against Pseudomonas infections, but we need more study and research. | ||
| Keywords | ||
| Pseudomonas aeruginosa; Ruta graveolens; Gentamicin | ||
| References | ||
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