| تعداد نشریات | 282 |
| تعداد نشریات سازمان | 80 |
| تعداد شمارهها | 3,219 |
| تعداد مقالات | 35,690 |
| تعداد مشاهده مقاله | 53,559,822 |
| تعداد دریافت فایل اصل مقاله | 92,840,235 |
Ecological Requirenments, Essential oil Composition, Total Phenol and Flavonoid Content, Antioxidant Activity and Ethnobotanical Survey of Ziziphora clinopodioides Lam. in North Khorasan Razavi Province | ||
| Journal of Medicinal plants and By-products | ||
| مقاله 9، دوره 4، شماره 2، آذر 2015، صفحه 193-199 اصل مقاله (221.41 K) | ||
| شناسه دیجیتال (DOI): 10.22092/jmpb.2015.108908 | ||
| نویسندگان | ||
| Masoumeh Mazandarani* ؛ Azam Ghaviandam Bovanloo | ||
| Department of Biology, Gorgan Branch, Islamic Azad University, Gorgan, Iran | ||
| چکیده | ||
| In several field observation of this research ,the main ecological requirenments and ethnopharmacological data about the traditional uses of Ziziphora clinopodioides Lam. were recorded. The aerial parts of plant were collected in blooming from Bovanloo mountain in September 2013 (1728 m ) in North Khorasan Razavi. Essential oil was obtained by hydro-distillation and analyzed by GC-MS. Methanolic extracts were obtained by maceration. Phytochemical assay: TP (total phenol) and TF (total flavonoid ) were determined by spectrophotometrically, antioxidant capacity were obtained by TAC, RP and DPPH methods in compare of BHT and BHA antioxidant standard. According to results, Ziziphora clinopodioides Lam. ( Kakuti ) is the most edible aromatic montainous herb, which wild growing in cold-dry climate (1500-1800 m) in North Khorasan Razavi province, with annual raining 288 mm, annual temperature 13.7 °C in sandy loam soil, with pH= 7.8 and Ec=0.8 dc. The pulegone (46.2%), menthol (10.7%), carvacrol (9.5%), 1,8-cineole (8.37%) , p-menthan-3-one (7.5) and piperitenone (5.8%) were the main constituents of plant essential oil. The amount of total phenolic (98.13±5.9 mg GAE 100 g-1 DW) and flavonoid contents (220.9±18.65 mg QE 100g-1 DW), respectively. The highest levels of IC50 (26.5 ± 1.4 μg/ml ) were detected in DPPH method against free radical scavenging in density of 5 μg/ml (P< 0.05) to compare of standard antioxidant (BHT and BHA). The essential oil and methanol extract of Ziziphora clinopodioides with high quality content and antioxidant activity can be confirmed the traditional uses of Z.clinopodioides in this provice as antiinflammation, antispasm, expectorant and antiinfection to treat of common cold, flu, fever, diarrhoae, gasterointestinal disorder and stomatchache in tea, yaghurt and doogh. | ||
| کلیدواژهها | ||
| Antioxidant؛ Autecology؛ essential oil composition؛ Ethnopharmacology؛ North Khorasan Razavi province TP and TF content؛ Ziziphora clinopodioides Lam | ||
| مراجع | ||
|
1. Rahnama M, Rohani SMR, Tajik H, Khalighi-Sigaroodi F, Rezazad-Bari M. Effects of Zataria multiflora Boiss. essential oil and nisin, alone and in combination against Listeria monocytogen in BHI broth. J Med. Plants.2009;8:120-131.
2. Mahboubia A, Kamalinejadb M, Ayatollahib CA.M, Babaeianb M. Total phenolic content and antibacterial activity of five plants of Labiatae against four foodborne and some other bacteria . Iran. J Pharm Res .2014; 13:559-566.
3. Mazandarani M, Osia N, Ghafourian M. Antioxidant activity and ethno pharmacological survey of Achillea biebersteinii Afan. in the treatment of dysmenorrhoea in traditional medicine of Golestan province, Iran. International .J Weamens Health . Rep.2015;2:107–110.
4. Rechinger KH, Satureja. In: Cavaleiro C, Salgueiro LR, Antunes T, editor(s). Flora Iranica. Graz, Austria: 1980; Sevinate.
5. Mozaffarian VA. Dictionary of iranian plant names. . Tehran, Iran: Farhang Moaser; 1996.
6. Langezaal CR. A pharmacognostic and pharmacological profile of Humulus lupulus L. J Ethnopharmacol .2008;116:383-396.
7. Salehi P, Sonboli A, Eftekhar F, Nejad Ebrahimi S, Yousef Zadi M. Essential oil composition, antibacterial and antioxidant activity of oils and various extracts of Ziziphora clinopodioides subsp rigida (Boiss). Rech. f. from Iran. Biol Pharm Bull .2005;28:1892-1896.
8. WHO Media Centre. Shigella, Helath Topics. [cited 2013 Jan 5]. Available from: URL: http://www.who.int/topics/shigella/en/.
9. Aliakbarlu J, Farnaz Shameli F. In vitro antioxidant and antibacterial properties and total phenolic contents of essential oils from Thymus vulgaris,T. kotschyanus, Ziziphora tenuior and Z. clinopodioides. Turk J Biochem. 2013;38;425-431.
10. Tzakou O, Skaltsa H. Composition and antibacterial activity of the essential oil of Satureja parnassica subsp parnassica. Planta Med. 2003;69:282-4. [PubMed].
11. Sadeghi I, Yousefzadi M, Behmanesh M, Sharifi M. In vitro cytotoxic and antimicrobial activity of essential oil from Satureja intermedia. C.J.M.B.Journal. 2013;15:70-4.
12. Sonboli A, Fakhari A, Kanani MR., Yousefzadi M. Antimicrobial activity, essential oil composition and micromorphology of trichomes of Satureja laxiflora C. Koch. from Iran. Z Naturforsch C . 2004;59:777-81. [PubMed].
13. Soltani SR, Shapouri R, Mola Abas Zade H, Modirrousta S. Evaluation of Antimicrobial Effect of Hops and Ziziphora clinopodioides extracts on intramacrophages Listeria omocytogenes by agar well diffusion method and cell culture of macrophage. Epidemiol. Med. 2013;1:27-32.
14. Behravan J, Ramezani M, Hassanzade MK,Eskandari M, Kasaian J, Sabeti Z. Composition, antimycotic and antibacterial activity of Ziziphora clinopodioides Lam. essential oil from Iran. J Essent Oil-Bearing plants .2007;10:339-345.
15. Pourmorad F, Hosseinimehr SJ, Shahabimajd N. Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plants. Afr J Biotech. 2006;5:1142-1145.
16. Arabshahi-Delouee S, UrooA. Antioxidant propperties of various solvent extracts of mulberry (Morus indical L.) leaves. Food chem. 2007;102:1233-1240.
17. Mazandarani M, Borhani G, Fathiazad F. Phytochemical analysis, antioxidant activity and ecological requirements of Capparis spinosa L. in Golestan and Semnan provinces (North of Iran). J Med Plants By-products .2014;1:21-26.
18. Nariman F, Eftekhar F, Habibi Z,Massarrat S, Malekzadeh R. Antibacterial activity of twenty iranian plant extracts against clinical isolates of Helicobacter pylori. Iran. J Basic Med. Sci. 2009;12:105-111.
19. Fazeli MR, Amin GR, Ahmadian Attari MM, Ashtiani H, Jamalifar H, Samadi N. Antimicrobial activities of Iranian sumac and avishan-e shirazi (Zataria multiflora) against some food-borne bacteria. Food Control. 2007; 18:646-649.
20. Fatemi F, Asri Y, Rasooli I, Alipoor ShD, Shaterloo M. Chemical composition and antioxidant properties of γ-irradiated Iranian Zataria multiflora extracts. Pharm. Biol.2012;50:232-238.
21. Sengul M, Yildiz H, Gungor N, Cetin B, Eser Z, Ercisli S. Total phenolic content, antioxidant and antimicrobial activities of some medicinal plants. Pak. J. Pharm. Sci. 2009;22:102-106.
22. Zendehdel M, Babapour V. Study of antinociceptive effects of Ziziphora tenuior and its interference on opioidergic and serotoninergic systems. J Vet. Res. 2010;65:57-60.
23. Serrano C, Matos O, Teixeira B, Ramos C, Neng N, NogueiraJ, Leonor Nunes M, Marques N. Antioxidant and antimicrobial activity of Satureja montana L. extracts. J Sci Food Agric. 2011; 9:1554–1560.
24. Esmaeili A, Rashidi B, Rezazadeh S. Biological activities of various extracts and chemical composition of Trigonella monantha C.A. Mey. subsp. monantha grown in Iran. Iran.J Pharm. Res. 2012;11:1127-1136.
25. Zali MR, Moez Ardalan K, Parcham Azad K, Nik-Kholgh B. Etiologies of acute diarrheal disease in iran. J. Res Med. Sci. 2003;7:346-356.
26. Khodaparast H, Mohammad Hosein M, Mehraban Sangatash M, Karazhyan M, Habibi Najafi R, Beiraghi Toosi Shahram MB . Effect of essential oil and extract of Ziziphora clinopodioides on yoghurt starter culture activity. World Applied Sci J. 2007;2:194-197.
27. Mazandarani M, Makari S, Bajian GhR., Zarghami Moghaddam P, Abrodi M. Evaluation of phytochemical and antioxidant activity in different parts of Heracleum gorganicum Rech. in Golestan province of Iran. Iranin J plant physiol. 2011;2:381-386. | ||
|
آمار تعداد مشاهده مقاله: 703 تعداد دریافت فایل اصل مقاله: 909 |
||