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Total Flavonoids Contents and Anti Bacterial Activity of the Extracts of two Labiateae Species: Nepeta menthoides and Thymus trautvetteri | ||
| Journal of Medicinal Plants and By-products | ||
| مقاله 11، دوره 4، شماره 1، تیر 2015، صفحه 77-82 اصل مقاله (101.5 K) | ||
| شناسه دیجیتال (DOI): 10.22092/jmpb.2015.108894 | ||
| نویسندگان | ||
| Shadi Ghandchi؛ Mina Jamzad* | ||
| Department of Chemistry, Shahr-e-Qods Branch, Islamic Azad University,Tehran, Iran | ||
| چکیده | ||
| Total flavonoids contents and antibacterial activity of the extracts from the aerial parts of two Labiateae species, Nepeta menthoides Boiss. & Buhse and Thymus trautvetteri Klokov & Desj.-Shost. were determined. Quantitative determination of flavonoid contents was calculated in terms of quercetin equivalent in various extracts (50% methanol, chloroform and distilled water) by AlCl3 colorimetric method. It was found that total flavonoids contents of N. menthoides extracts in different solvents were (2.308%, 0.884% and 0.710%) mg/g and (2.076%, 1.468% and 1.412%) mg/g for T. trautvetteri respectively.Antibacterial activity of the extracts was also determined against 6 gr (+/-) bacteria by disc diffusion method. The results showed that 50% methanol extracts of two species displayed better inhibitor activity against the tested bacteria. The bacteria Stapylococcus epidermidis, Staphylococcus saprophyticus and Staphylococcus aureus were sensitive against 50% methanol extract of N. menthoides even more than the standard antibiotics (10μg). Therefore a good correlation between total flavonoids contents and antibacterial activity of the studied extracts is demonstrated. | ||
| کلیدواژه‌ها | ||
| Nepeta menthoides؛ Thymus trautvetteri؛ Flavonoids contents؛ Antibacterial activity | ||
| مراجع | ||
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