Correlation between methylmercury accumulation in the kidney and liver and some biochemical parameters of blood sera in juvenile beluga (Huso huso) | ||
| تحقیقات دامپزشکی و فرآوردههای بیولوژیک | ||
| Editorial, Volume 23, Issue 3, September 2010, Pages 34-39 PDF (537.91 K) | ||
| Authors | ||
| A Gharaei* ; M Ghaffari | ||
| Department of Fisheries, Hamoun International Wetland Research Institute, University of Zabol, Zabol, Sistan & Balouchestan, Iran | ||
| Abstract | ||
| In this study, correlation between Methylmercury (MeHg) accumulation in the kidney and liver and several blood biochemical parameters juvenile beluga (Huso huso) including aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), glucose (GLU), and Cortisol was investigated. To do this, juvenile beluga were fed with two different diets containing MeHg (control: 0.04 mg kg-1 and 0.76 mg kg-1 low treatment) for 32 days. The results showed significant increase (P<0.01, P<0.05) in all biochemical parameters except ALP level compared with the control group during the experiment. A survey of correlation between MeHg accumulation in the two organs (kidney and liver) and the biochemical parameters of blood sera showed that the levels of ALT, GLU and Cortisol parameters in kidney and ALT and AST in liver were highly correlated with accumulation of MeHg, whereas LDH enzyme level was the lowest correlation in both organs. The results suggested that the sera biochemical parameters under investigation can be used as enzyme biomarkers to assess toxicity induction by MeHg. | ||
| References | ||
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