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بررسی تاثیر بیهوشی با پروپوفول بر برخی فاکتورهای بیوشیمیایی سرم خون ماهی کپور علفخوار، Ctenopharyngodon idella | ||
| تحقیقات دامپزشکی و فرآوردههای بیولوژیک | ||
| شناسنامه علمی شماره، دوره 26، شماره 3، مهر 1392، صفحه 16-22 اصل مقاله (453.32 K) | ||
| شناسه دیجیتال (DOI): 10.22092/vj.2013.101019 | ||
| نویسندگان | ||
| رحیم پیغان* 1؛ غلامحسین خواجه1؛ هادی نداف2؛ سارا لرکی3 | ||
| 1استاد، گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه شهید چمران اهواز | ||
| 2دانشیار، گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه شهید چمران اهواز | ||
| 3دانش آموخته دانشکده دامپزشکی دانشگاه شهید چمران اهواز | ||
| چکیده | ||
| به منظور بررسی اثر غلظت های مختلف داروی بیهوشی پروپوفول بر برخی پارامترهای بیوشیمیایی سرم خون، تعداد 120 قطعه ماهی کپور علفخوار به دو روش غوطه وری و تزریق داخل وریدی بیهوش گردیدند. از ماهی ها در حین بیهوشی و 4 روز پس از آن خون گیری به عمل آمد. در روش غوطه وری میانگین میزان پتاسیم در همه غلظت ها و میانگین مقدار اوره و ازت اوره خون در غلظت 4 میلی گرم بر لیتر در حین بیهوشی با پروپوفول به ترتیب بطور معنی داری بیشتر و کمتر از گروه شاهد بودند. در این روش غلظت کلسیم، فسفر، پتاسیم و کلسترول در زمان بیهوشی و 4 روز پس از آن تفاوت معنی دار داشتند. در روش تزریق داخل وریدی میانگین غلظت کلسیم و میانگین مقدار کلر، سدیم و پتاسیم در حین بیهوشی با پروپوفول به ترتیب بطور معنی داری کمتر و بیشتر از گروه شاهد بودند. در 4 روز پس از بیهوشی نیز میانگین میزان سدیم و پتاسیم افزایش معنی داری در مقایسه با گروه شاهد داشت. بطور کلی به نظر می رسد پروپوفول تاثیر قابل توجهی بر فاکتورهای بیوشیمیایی خون ماهی مورد مطالعه داشت اگر چه تغییرات مشاهده شده عموماً در محدوده طبیعی و قابل قبول قرار دارد. | ||
| عنوان مقاله [English] | ||
| Effect of anesthesia with propofol on biochemical parameters of serum in grass carp (Ctenopharyngodon idella) | ||
| نویسندگان [English] | ||
| R Peyghan1؛ G.H Khadjeh1؛ H Nadaf2؛ S Larki3 | ||
| 1Professor, Clinical Sciences Department, Veterinary Faculty, Shahid Chamran University of Ahvaz, Ahvaz-Iran. | ||
| 2Associate Professor, Clinical Sciences Department, Veterinary Faculty, Shahid Chamran University of Ahvaz, Ahvaz-Iran | ||
| 3Graduated Student, Veterinary Faculty, Shahid Chamran University. Ahvaz-Iran | ||
| چکیده [English] | ||
| In this study for determinination of effects of anesthesia with propofol on some of biochemical factors of blood, 120 grass carp were chosen. The fish were exposed to the ascending concentration of propofol by bath method and injection method. At the time of anesthesia and 4 days after anesthesia blood samples were taken from the caudal vein and some biochemical parameters of blood were measured and compared. At anesthesia with propofol, in bath method the mean of potassium was significantly higher than the control group. At the time of anesthesia the mean of phosphorus, blood urea nitrogen (BUN) and urea were significantly lower than the control group and in 4 days after anesthesia. The mean of calcium, phosphorus and cholesterol were significantly lower than the control group. The mean of calcium, phosphorus and cholesterol at the time of anesthesia were significantly higher than their means in 4 days after anesthesia whith propofol, but the mean of potassium at the time of anesthesia was significantly lower than their mean in 4 days after anesthesia. At the time of anesthesia with propofol, in injection method the mean of sodium and potassium, cholorid were significantly higher than the control group and in 4 days after anesthesia the mean of sodium and potassium were significantly higher than the control group. These results showed that propofol have had a markrd effect on biochemichal factores of blood serum, however the changes had been in normal range for the studied factors. | ||
| مراجع | ||
|
1- Barnhart, R.A. (1969) Effects of certain variable on haematological characteristics of rainbow trout. Salmo garidneri (Richardson). Transactions of the American Fisheries Society. 98: 411- 418.##
2- Booth, N.H. and Mcdonold. E. (1988) Veterinary pharmacology and Therapeutics. 6th ed. State University Press, Amsterdam, Iowa. PP: 165-167, 253-265.##
3- Bruecker, P. and Graham. M. (1993) The effects of the anesthetic ketamine hydrocholoride on oxygen consumption rates and behavior in the fish Hores citrinellam. Comparative Biochemistry and Physiology. 104: 57-59.##
4- Cataldi, E., Dimarco, P., Mandich, A. and Cataudella, S. (1998) Serum parameters of adriatic sturgeon Acipenser naccarri (Pisces: Acipenseriforms): Effects of temperature and stress. Comparative Biochemistry and Physiology. A., 121: 351-354. ##
5- Cotter, P.A. and Rodnick, K.J. (2006) Differential effects of anesthetics on electrical properties of the rainbow trout (Oncorhynchus mykiss) heart. Comparative Biochemistry and Physiology. Part A. 145: 158–165.##
6- Ferreire, J.T., Smit, G.L. and Schoonbee, H.J. (1981) The effect of the anesthetic benzocaine hydrochloride on red cell fragilities in Cyprinus carpio. Journal of Fish Biology. 18: 123-126.##
7- Graham, M.S. and Iwana, G.K. (1990) The physiologic effects of the anesthetic ketamine hydrochloride on two salmonid species. Aquaculture. 90: 323-331.##
8- Iwama, G. K., Mcgeer, J. C. and Pawluk, M. P. (1989) The effect of five fish anesthetics on acid-base balance, hematocrit, blood gasses, cortisol and adrenaline in rainbow trout. Canadian Journal of Zoology. 67: 2065-2073.##
9- Korstrom, J. S., Birtwell T, K., Piercey, G. E., Spohn, S., Langton, C. M. and Kruzynski, G. M. (1996) Effect of hypoxia, fresh water, anesthesia and sampeling technique on the hematocrit value of adult sockeye salmon, Oncorhynchus nerka. Canadian Technical Report of Fisheries and Aquatic Sciences. 2101. pp: 34.##
10- Lee, J.K. and Kwan, H.B. (1994) Effect of repeated halothane anesthesia on canine haematology and blood chemistry. Korean Journal of Veterinay Clinical medicine. 11: 169.##
11- Nagashiyama, Y. and Furkawa, Y. (2000) Propofol increase contractility of isolated blood-perfused left ventricular muscle in the dog. Journal of Anesthesia. 14: 45-47.##
12- Pirhonen, J. and Schreck, C.B. (2003) Effects of anaesthesia with MS-222, clove oil and CO2 on feed intake and plasma cortisol in steelhead trout (Oncorhynchus mykiss). Aquaculture. 220: 507–514. ##
13- Palić, D., Herolt, D.M., Andreasen, C.B., Menzel, B.W. and Roth, J.A. (2006) Anesthetic efficacy of tricaine methanesulfonate, metomidate and eugenol: Effects on plasma cortisol concentration and neutrophil function in fathead minnows (Pimephales promelas Rafinesque, 1820). Aquaculture. 254: 675–685.##
14- Rajaian H. (1993) Haematologiacal and biochemical changes due to halothane in sheep. Indian Veterinary Journal. 70 : 622-625.##
15- Rothwell, S.E., Black, S.E., Jerrett, A.R. and Forster, M.E. (2005) Cardiovascular changes and catecholamine release following anaesthesia in Chinook salmon (Oncorhynchus tshawytscha) and snapper (Pagrus auratus). Comparative Biochemistry and Physiology. Part A. 140 : 289– 298.##
16- Sebel, P. and Lowdon, J. (1989) Propofol: A new intravenous anesthetic. Anesthesiology. 71 : 260-277. ##
17- Soivio, A., Nyholm, K. and Huhti, M. (1977) Effect of anesthesia with MS-222, neutralized MS-222 and benzocaine on the blood constituents of rainbow trout, Salmo gairdneri. Journal of fish Bioligy. 10 : 91-101.##
18- Thrall, M. A. (2004) Veterinary Hematology and Clinical Chemistry. Lippincott Williams and Willkins, USA, pp: 277-288, 494-503.##
19- Watt, E.E., Betts, B.A., Kotey, F.O., Humbert, D.J., Griffith, T.N., Kelly, E.W., Veneskey, K.C., Gill, N., Rowan, K.C., Jenkins, A. and Hall, A.C. (2008) Menthol shares general anesthetic activity and sites of action on the GABA receptor with the intravenous agent, propofol. European Journal of Pharmacology. 590 : 120–126.## | ||
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